STRINGSTRING
TRA2B TRA2B DDX23 DDX23 PPIL1 PPIL1 BUD13 BUD13 SRSF1 SRSF1 TXNL4A TXNL4A GPKOW GPKOW RBM8A RBM8A ENSEEUP00000007978 ENSEEUP00000007978 EIF4A2 EIF4A2 GEMIN2 GEMIN2 YJU2 YJU2 PRPF39 PRPF39 GPATCH11 GPATCH11 ENSEEUP00000007143 ENSEEUP00000007143 ZMAT2 ZMAT2 PRPF19 PRPF19 ENSEEUP00000006849 ENSEEUP00000006849 PRPF4 PRPF4 LOC103123420 LOC103123420 PRPF3 PRPF3 PPP1R8 PPP1R8 PRPF40B PRPF40B SNW1 SNW1 DNAJC17 DNAJC17 CWC25 CWC25 RNPC3 RNPC3 ENSEEUP00000012210 ENSEEUP00000012210 SNRPF SNRPF SNRPB2 SNRPB2 SRRM1 SRRM1 ENSEEUP00000012701 ENSEEUP00000012701 ENSEEUP00000012819 ENSEEUP00000012819 SRRM2 SRRM2 CASC3 CASC3 ENSEEUP00000013058 ENSEEUP00000013058 PRPF38B PRPF38B ENSEEUP00000013081 ENSEEUP00000013081 CWF19L1 CWF19L1 SNIP1 SNIP1 SNRPC SNRPC FRG1 FRG1 ADAR ADAR ENSEEUP00000013630 ENSEEUP00000013630 DDX39A DDX39A SYF2 SYF2 SNRPA SNRPA MFAP1 MFAP1 ZCCHC8 ZCCHC8 PLRG1 PLRG1 ENSEEUP00000014016 ENSEEUP00000014016 SNRNP48 SNRNP48 SNRPD3 SNRPD3 SNRPB SNRPB SF3B3 SF3B3 TRA2A TRA2A TFIP11 TFIP11 ALYREF ALYREF PPIE PPIE HTATSF1 HTATSF1 CLNS1A CLNS1A ENSEEUP00000010068 ENSEEUP00000010068 CWF19L2 CWF19L2 EFTUD2 EFTUD2 CDC5L CDC5L PRPF4B PRPF4B SNRPG SNRPG RBM41 RBM41 MYEF2 MYEF2 DHX35 DHX35 SLU7 SLU7 LOC103115403 LOC103115403 SNRPE SNRPE PRPF31 PRPF31 EIF4A3 EIF4A3 SMNDC1 SMNDC1 ENSEEUP00000005348 ENSEEUP00000005348 SNRNP35 SNRNP35 DHX16 DHX16 CWC27 CWC27 ENSEEUP00000010964 ENSEEUP00000010964 SMU1 SMU1 ENSEEUP00000005228 ENSEEUP00000005228 SNRNP70 SNRNP70 RBM22 RBM22 PNN PNN API5-2 API5-2 CWC22 CWC22 LOC103126981 LOC103126981 SNRPD1 SNRPD1 DHX8 DHX8 ENSEEUP00000004366 ENSEEUP00000004366 DHX15 DHX15 LUC7L3 LUC7L3 ZNF830 ZNF830 WBP4 WBP4 SYNCRIP SYNCRIP SNRPA1 SNRPA1 HNRNPU HNRNPU AAR2 AAR2 API5 API5 AQR AQR ENSEEUP00000003510 ENSEEUP00000003510 ENSEEUP00000003106 ENSEEUP00000003106 ENSEEUP00000002929 ENSEEUP00000002929 SF3A1 SF3A1 C9orf78 C9orf78 PPIL2 PPIL2 PABPC1 PABPC1 CDC40 CDC40 DHX38 DHX38 CWC15 CWC15 ZRSR2 ZRSR2 LSM6 LSM6 BUD31 BUD31 ENSEEUP00000001770 ENSEEUP00000001770 ENSEEUP00000001752 ENSEEUP00000001752 DDX41 DDX41 CTNNBL1 CTNNBL1 ENSEEUP00000001197 ENSEEUP00000001197 ENSEEUP00000001055 ENSEEUP00000001055 SF1 SF1 ZMAT5 ZMAT5 RBMX2 RBMX2 SF3B1 SF3B1 MTREX MTREX CRNKL1 CRNKL1 ZCRB1 ZCRB1 TXNL4B TXNL4B PRPF6 PRPF6 ENSEEUP00000011134 ENSEEUP00000011134 SNRNP200 SNRNP200 LOC103115402 LOC103115402 ENSEEUP00000011279 ENSEEUP00000011279 HSPA8 HSPA8 WBP11 WBP11 GPATCH1 GPATCH1 RBM17 RBM17 HNRNPR HNRNPR PTBP2 PTBP2 ENSEEUP00000009063 ENSEEUP00000009063 ENSEEUP00000008944 ENSEEUP00000008944
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRA2BTransformer-2 protein homolog beta isoform X2. (248 aa)
DDX23Probable ATP-dependent RNA helicase DDX23. (822 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (106 aa)
BUD13BUD13 homolog. (538 aa)
SRSF1Serine/arginine-rich splicing factor 1 isoform X2. (292 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (91 aa)
GPKOWG patch domain and KOW motifs-containing protein isoform X2. (472 aa)
RBM8ARNA binding motif protein 8A. (174 aa)
ENSEEUP00000007978annotation not available (156 aa)
EIF4A2Eukaryotic translation initiation factor 4A2. (279 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (278 aa)
YJU2YJU2 splicing factor homolog. (231 aa)
PRPF39pre-mRNA-processing factor 39 isoform X2. (527 aa)
GPATCH11G patch domain-containing protein 11 isoform X2. (252 aa)
ENSEEUP00000007143annotation not available (188 aa)
ZMAT2Zinc finger matrin-type protein 2. (152 aa)
PRPF19pre-mRNA-processing factor 19. (504 aa)
ENSEEUP00000006849annotation not available (116 aa)
PRPF4pre-mRNA processing factor 4. (458 aa)
LOC103123420Small nuclear ribonucleoprotein-associated protein. (239 aa)
PRPF3U4/U6 small nuclear ribonucleoprotein Prp3. (681 aa)
PPP1R8Nuclear inhibitor of protein phosphatase 1 isoform X1. (351 aa)
PRPF40Bpre-mRNA-processing factor 40 homolog B isoform X3. (772 aa)
SNW1SNW domain-containing protein 1. (536 aa)
DNAJC17DnaJ heat shock protein family (Hsp40) member C17. (304 aa)
CWC25pre-mRNA-splicing factor CWC25 homolog. (322 aa)
RNPC3RNA-binding protein 40 isoform X1. (64 aa)
ENSEEUP00000012210annotation not available (198 aa)
SNRPFSmall nuclear ribonucleoprotein F. (85 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'. (225 aa)
SRRM1Serine/arginine repetitive matrix protein 1 isoform X1. (912 aa)
ENSEEUP00000012701annotation not available (267 aa)
ENSEEUP00000012819annotation not available (126 aa)
SRRM2Serine/arginine repetitive matrix protein 2 isoform X1. (2615 aa)
CASC3Protein CASC3. (511 aa)
ENSEEUP00000013058annotation not available (891 aa)
PRPF38Bpre-mRNA-splicing factor 38B. (541 aa)
ENSEEUP00000013081annotation not available (358 aa)
CWF19L1CWF19-like protein 1 isoform X1. (533 aa)
SNIP1Smad nuclear-interacting protein 1. (286 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (175 aa)
FRG1Protein FRG1 isoform X2. (157 aa)
ADARDouble-stranded RNA-specific adenosine deaminase isoform X1. (1159 aa)
ENSEEUP00000013630annotation not available (102 aa)
DDX39AATP-dependent RNA helicase DDX39A. (422 aa)
SYF2pre-mRNA-splicing factor SYF2. (183 aa)
SNRPAU1 small nuclear ribonucleoprotein A isoform X1. (282 aa)
MFAP1Microfibrillar-associated protein 1. (412 aa)
ZCCHC8Zinc finger CCHC domain-containing protein 8. (710 aa)
PLRG1Pleiotropic regulator 1. (502 aa)
ENSEEUP00000014016annotation not available (314 aa)
SNRNP48U11/U12 small nuclear ribonucleoprotein 48 kDa protein. (339 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (125 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (284 aa)
SF3B3Splicing factor 3B subunit 3. (1216 aa)
TRA2ATransformer-2 protein homolog alpha isoform X1. (282 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (738 aa)
ALYREFTHO complex subunit 4. (171 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (279 aa)
HTATSF1HIV Tat-specific factor 1. (761 aa)
CLNS1AMethylosome subunit pICln. (214 aa)
ENSEEUP00000010068annotation not available (386 aa)
CWF19L2CWF19-like protein 2. (740 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component. (881 aa)
CDC5LCell division cycle 5-like protein. (801 aa)
PRPF4BSerine/threonine-protein kinase PRP4 homolog. (1004 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
RBM41RNA-binding protein 41. (409 aa)
MYEF2Heterogeneous nuclear ribonucleoprotein M. (600 aa)
DHX35Probable ATP-dependent RNA helicase DHX35 isoform X1. (707 aa)
SLU7pre-mRNA-splicing factor SLU7. (586 aa)
LOC103115403UPF0562 protein C7orf55 homolog. (141 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
PRPF31U4/U6 small nuclear ribonucleoprotein Prp31 isoform X3. (384 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
SMNDC1Survival of motor neuron-related-splicing factor 30 isoform X1. (238 aa)
ENSEEUP00000005348annotation not available (642 aa)
SNRNP35U11/U12 small nuclear ribonucleoprotein 35 kDa protein. (247 aa)
DHX16Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16. (887 aa)
CWC27Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1. (472 aa)
ENSEEUP00000010964annotation not available (313 aa)
SMU1WD40 repeat-containing protein SMU1. (513 aa)
ENSEEUP00000005228annotation not available (95 aa)
SNRNP70U1 small nuclear ribonucleoprotein 70 kDa. (437 aa)
RBM22pre-mRNA-splicing factor RBM22. (419 aa)
PNNPinin isoform X2. (711 aa)
API5-2Apoptosis inhibitor 5 isoform X2. (285 aa)
CWC22pre-mRNA-splicing factor CWC22 homolog. (897 aa)
LOC103126981UPF0692 protein C19orf54 homolog. (179 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (89 aa)
DHX8ATP-dependent RNA helicase DHX8 isoform X2. (1220 aa)
ENSEEUP00000004366annotation not available (627 aa)
DHX15pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 isoform X1. (795 aa)
LUC7L3Luc7-like protein 3 isoform X2. (432 aa)
ZNF830Zinc finger protein 830. (361 aa)
WBP4WW domain-binding protein 4. (347 aa)
SYNCRIPHeterogeneous nuclear ribonucleoprotein Q isoform X7. (605 aa)
SNRPA1LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein A. (254 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (550 aa)
AAR2Protein AAR2 homolog. (384 aa)
API5Apoptosis inhibitor 5 isoform X4. (443 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1517 aa)
ENSEEUP00000003510annotation not available (586 aa)
ENSEEUP00000003106annotation not available (394 aa)
ENSEEUP00000002929annotation not available (556 aa)
SF3A1Splicing factor 3A subunit 1. (701 aa)
C9orf78Chromosome 9 open reading frame 78. (259 aa)
PPIL2Peptidyl-prolyl cis-trans isomerase-like 2. (520 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (567 aa)
CDC40pre-mRNA-processing factor 17. (568 aa)
DHX38pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1119 aa)
CWC15Spliceosome-associated protein CWC15 homolog. (231 aa)
ZRSR2U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2. (473 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (78 aa)
BUD31Protein BUD31 homolog. (144 aa)
ENSEEUP00000001770annotation not available (544 aa)
ENSEEUP00000001752annotation not available (65 aa)
DDX41Probable ATP-dependent RNA helicase DDX41. (570 aa)
CTNNBL1Beta-catenin-like protein 1. (568 aa)
ENSEEUP00000001197annotation not available (599 aa)
ENSEEUP00000001055annotation not available (315 aa)
SF1Splicing factor 1 isoform X1. (393 aa)
ZMAT5Zinc finger matrin-type protein 5 isoform X2. (165 aa)
RBMX2RNA-binding motif protein, X-linked 2 isoform X1. (211 aa)
SF3B1Splicing factor 3B subunit 1 isoform X1. (1299 aa)
MTREXSuperkiller viralicidic activity 2-like 2 isoform X1. (1025 aa)
CRNKL1Crooked neck-like protein 1. (744 aa)
ZCRB1Zinc finger CCHC-type and RNA-binding motif-containing protein 1. (215 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (146 aa)
PRPF6pre-mRNA processing factor 6. (938 aa)
ENSEEUP00000011134annotation not available (2333 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2018 aa)
LOC103115402Putative RNA-binding protein Luc7-like 2 isoform X4. (367 aa)
ENSEEUP00000011279annotation not available (475 aa)
HSPA8Heat shock cognate 71 kDa protein; Belongs to the heat shock protein 70 family. (532 aa)
WBP11WW domain-binding protein 11. (639 aa)
GPATCH1G-patch domain containing 1. (930 aa)
RBM17Splicing factor 45. (333 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R isoform X1. (511 aa)
PTBP2Polypyrimidine tract-binding protein 2 isoform X1. (534 aa)
ENSEEUP00000009063annotation not available (857 aa)
ENSEEUP00000008944annotation not available (395 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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