STRINGSTRING
DSCC1 DSCC1 HELB HELB PIF1 PIF1 DHX9 DHX9 ENSEEUP00000004885 ENSEEUP00000004885 ENSEEUP00000005927 ENSEEUP00000005927 ENSEEUP00000007672 ENSEEUP00000007672 RFC4 RFC4 DNA2 DNA2 RFC3 RFC3 WRNIP1 WRNIP1 POLQ POLQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DSCC1DNA replication and sister chromatid cohesion 1. (279 aa)
HELBDNA helicase B. (1070 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (436 aa)
DHX9ATP-dependent RNA helicase A isoform X1. (1265 aa)
ENSEEUP00000004885annotation not available (315 aa)
ENSEEUP00000005927annotation not available (647 aa)
ENSEEUP00000007672annotation not available (902 aa)
RFC4Replication factor C subunit 4. (363 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (924 aa)
RFC3Replication factor C subunit 3. (353 aa)
WRNIP1ATPase WRNIP1 isoform X1. (533 aa)
POLQDNA polymerase theta. (2561 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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