(37 nodes) Negative regulation of DNA recombination network (Erinaceus europaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BCL6	B-cell lymphoma 6 protein. (708 aa)
	FBH1	F-box DNA helicase 1 isoform X1. (977 aa)
	LOC103123891	Histone H1.3. (190 aa)
	PARP3	Poly [ADP-ribose] polymerase. (536 aa)
	POLQ	DNA polymerase theta. (2561 aa)
	BLM	Bloom syndrome protein. (1383 aa)
	H1-2	Histone H1.2. (212 aa)
	H1-5	Histone H1.5. (225 aa)
	HELB	DNA helicase B. (1070 aa)
	ENSEEUP00000003620	annotation not available (206 aa)
	KLHL15	Kelch-like protein 15 isoform X2. (425 aa)
	MAD2L2	Mitotic spindle assembly checkpoint protein MAD2B. (216 aa)
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1139 aa)
	SMCHD1	Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (1290 aa)
	ENSEEUP00000006554	annotation not available (397 aa)
	ENSEEUP00000006572	annotation not available (1974 aa)
	PARPBP	PCNA-interacting partner. (500 aa)
	RADX	Uncharacterized protein CXorf57 homolog. (645 aa)
	ENSEEUP00000008137	annotation not available (338 aa)
	ENSEEUP00000008743	annotation not available (183 aa)
	MB21D1	Cyclic GMP-AMP synthase. (296 aa)
	RECQL5	ATP-dependent DNA helicase Q5. (979 aa)
	LOC107522660	Spermatid-specific linker histone H1-like protein. (229 aa)
	NDFIP1	NEDD4 family-interacting protein 1. (175 aa)
	ZRANB3	DNA annealing helicase and endonuclease ZRANB3 isoform X1. (1000 aa)
	ENSEEUP00000010545	annotation not available (372 aa)
	H1-6	Histone H1t. (214 aa)
	ENSEEUP00000010627	annotation not available (1121 aa)
	ENSEEUP00000011153	annotation not available (638 aa)
	ENSEEUP00000011377	annotation not available (827 aa)
	ENSEEUP00000011467	annotation not available (851 aa)
	H1-1	Histone H1.1. (216 aa)
	RIF1	Replication timing regulatory factor 1. (2367 aa)
	ENSEEUP00000012233	annotation not available (301 aa)
	NSMCE3	Non-structural maintenance of chromosomes element 3 homolog. (286 aa)
	MSH2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa)
	H1-4	Histone H1.4. (220 aa)

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	ENSEEUP00000010545	ENSEEUP00000000302	ENSEEUP00000010545	B-cell lymphoma 6 protein.	annotation not available	0.860
BLM	ENSEEUP00000006554	ENSEEUP00000001297	ENSEEUP00000006554	Bloom syndrome protein.	annotation not available	0.572
BLM	ENSEEUP00000006572	ENSEEUP00000001297	ENSEEUP00000006572	Bloom syndrome protein.	annotation not available	0.894
BLM	ENSEEUP00000008137	ENSEEUP00000001297	ENSEEUP00000008137	Bloom syndrome protein.	annotation not available	0.712
BLM	ENSEEUP00000010627	ENSEEUP00000001297	ENSEEUP00000010627	Bloom syndrome protein.	annotation not available	0.681
BLM	ENSEEUP00000011377	ENSEEUP00000001297	ENSEEUP00000011377	Bloom syndrome protein.	annotation not available	0.530
BLM	FBH1	ENSEEUP00000001297	ENSEEUP00000000409	Bloom syndrome protein.	F-box DNA helicase 1 isoform X1.	0.944
BLM	HELB	ENSEEUP00000001297	ENSEEUP00000002796	Bloom syndrome protein.	DNA helicase B.	0.620
BLM	MSH2	ENSEEUP00000001297	ENSEEUP00000014300	Bloom syndrome protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.790
BLM	MSH6	ENSEEUP00000001297	ENSEEUP00000005594	Bloom syndrome protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.907
BLM	POLQ	ENSEEUP00000001297	ENSEEUP00000000949	Bloom syndrome protein.	DNA polymerase theta.	0.793
BLM	RECQL5	ENSEEUP00000001297	ENSEEUP00000009070	Bloom syndrome protein.	ATP-dependent DNA helicase Q5.	0.722
BLM	RIF1	ENSEEUP00000001297	ENSEEUP00000012060	Bloom syndrome protein.	Replication timing regulatory factor 1.	0.684
BLM	ZRANB3	ENSEEUP00000001297	ENSEEUP00000010258	Bloom syndrome protein.	DNA annealing helicase and endonuclease ZRANB3 isoform X1.	0.400
ENSEEUP00000003620	ENSEEUP00000011377	ENSEEUP00000003620	ENSEEUP00000011377	annotation not available	annotation not available	0.913
ENSEEUP00000003620	MAD2L2	ENSEEUP00000003620	ENSEEUP00000005386	annotation not available	Mitotic spindle assembly checkpoint protein MAD2B.	0.554
ENSEEUP00000006554	BLM	ENSEEUP00000006554	ENSEEUP00000001297	annotation not available	Bloom syndrome protein.	0.572
ENSEEUP00000006554	ENSEEUP00000006572	ENSEEUP00000006554	ENSEEUP00000006572	annotation not available	annotation not available	0.490
ENSEEUP00000006554	ENSEEUP00000008137	ENSEEUP00000006554	ENSEEUP00000008137	annotation not available	annotation not available	0.994
ENSEEUP00000006554	RECQL5	ENSEEUP00000006554	ENSEEUP00000009070	annotation not available	ATP-dependent DNA helicase Q5.	0.533