STRINGSTRING
SIRT1 SIRT1 CUL4B CUL4B XPC XPC ACTR5 ACTR5 DDB1 DDB1 ENSEEUP00000002984 ENSEEUP00000002984 XPA XPA POLD3 POLD3 INO80 INO80 ERCC1 ERCC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIRT1NAD-dependent protein deacetylase sirtuin-1. (595 aa)
CUL4Bcullin-4B isoform X1; Belongs to the cullin family. (893 aa)
XPCDNA repair protein complementing XP-C cells. (912 aa)
ACTR5Actin-related protein 5; Belongs to the actin family. (607 aa)
DDB1DNA damage-binding protein 1. (1138 aa)
ENSEEUP00000002984annotation not available (425 aa)
XPADNA repair protein complementing XP-A cells. (214 aa)
POLD3DNA polymerase delta subunit 3. (404 aa)
INO80DNA helicase INO80. (1532 aa)
ERCC1DNA excision repair protein ERCC-1 isoform X2. (232 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.