STRINGSTRING
PNN PNN RBM22 RBM22 ENSEEUP00000005228 ENSEEUP00000005228 ENSEEUP00000005348 ENSEEUP00000005348 EIF4A3 EIF4A3 SLU7 SLU7 DHX35 DHX35 SNRPG SNRPG PRPF4B PRPF4B CDC5L CDC5L SNW1 SNW1 PPIE PPIE LOC103123420 LOC103123420 ENSEEUP00000006849 ENSEEUP00000006849 PRPF19 PRPF19 ENSEEUP00000007143 ENSEEUP00000007143 EIF4A2 EIF4A2 ENSEEUP00000007978 ENSEEUP00000007978 RBM8A RBM8A SRSF1 SRSF1 PPIL1 PPIL1 DDX23 DDX23 ENSEEUP00000008944 ENSEEUP00000008944 HNRNPR HNRNPR FRG1 FRG1 PRPF6 PRPF6 CRNKL1 CRNKL1 MTREX MTREX SF3B1 SF3B1 DDX41 DDX41 ENSEEUP00000001752 ENSEEUP00000001752 BUD31 BUD31 CWC15 CWC15 DHX38 DHX38 CDC40 CDC40 PABPC1 PABPC1 PPIL2 PPIL2 SF3A1 SF3A1 ENSEEUP00000003510 ENSEEUP00000003510 AQR AQR HNRNPU HNRNPU SNRPA1 SNRPA1 SYNCRIP SYNCRIP DHX8 DHX8 SNRPD1 SNRPD1 LOC103126981 LOC103126981 CWC22 CWC22 TFIP11 TFIP11 SF3B3 SF3B3 SNRPB SNRPB SNRPD3 SNRPD3 ENSEEUP00000014016 ENSEEUP00000014016 PLRG1 PLRG1 ZCCHC8 ZCCHC8 SYF2 SYF2 ENSEEUP00000013630 ENSEEUP00000013630 ENSEEUP00000013081 ENSEEUP00000013081 EFTUD2 EFTUD2 CWC27 CWC27 ENSEEUP00000011134 ENSEEUP00000011134 SNRNP200 SNRNP200 ENSEEUP00000011279 ENSEEUP00000011279 GPATCH1 GPATCH1 SNRPF SNRPF SNRPB2 SNRPB2 SRRM1 SRRM1 ENSEEUP00000012819 ENSEEUP00000012819 SRRM2 SRRM2 ENSEEUP00000013058 ENSEEUP00000013058
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNNPinin isoform X2. (711 aa)
RBM22pre-mRNA-splicing factor RBM22. (419 aa)
ENSEEUP00000005228annotation not available (95 aa)
ENSEEUP00000005348annotation not available (642 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
SLU7pre-mRNA-splicing factor SLU7. (586 aa)
DHX35Probable ATP-dependent RNA helicase DHX35 isoform X1. (707 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
PRPF4BSerine/threonine-protein kinase PRP4 homolog. (1004 aa)
CDC5LCell division cycle 5-like protein. (801 aa)
SNW1SNW domain-containing protein 1. (536 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (279 aa)
LOC103123420Small nuclear ribonucleoprotein-associated protein. (239 aa)
ENSEEUP00000006849annotation not available (116 aa)
PRPF19pre-mRNA-processing factor 19. (504 aa)
ENSEEUP00000007143annotation not available (188 aa)
EIF4A2Eukaryotic translation initiation factor 4A2. (279 aa)
ENSEEUP00000007978annotation not available (156 aa)
RBM8ARNA binding motif protein 8A. (174 aa)
SRSF1Serine/arginine-rich splicing factor 1 isoform X2. (292 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (106 aa)
DDX23Probable ATP-dependent RNA helicase DDX23. (822 aa)
ENSEEUP00000008944annotation not available (395 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R isoform X1. (511 aa)
FRG1Protein FRG1 isoform X2. (157 aa)
PRPF6pre-mRNA processing factor 6. (938 aa)
CRNKL1Crooked neck-like protein 1. (744 aa)
MTREXSuperkiller viralicidic activity 2-like 2 isoform X1. (1025 aa)
SF3B1Splicing factor 3B subunit 1 isoform X1. (1299 aa)
DDX41Probable ATP-dependent RNA helicase DDX41. (570 aa)
ENSEEUP00000001752annotation not available (65 aa)
BUD31Protein BUD31 homolog. (144 aa)
CWC15Spliceosome-associated protein CWC15 homolog. (231 aa)
DHX38pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1119 aa)
CDC40pre-mRNA-processing factor 17. (568 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (567 aa)
PPIL2Peptidyl-prolyl cis-trans isomerase-like 2. (520 aa)
SF3A1Splicing factor 3A subunit 1. (701 aa)
ENSEEUP00000003510annotation not available (586 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1517 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (550 aa)
SNRPA1LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein A. (254 aa)
SYNCRIPHeterogeneous nuclear ribonucleoprotein Q isoform X7. (605 aa)
DHX8ATP-dependent RNA helicase DHX8 isoform X2. (1220 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (89 aa)
LOC103126981UPF0692 protein C19orf54 homolog. (179 aa)
CWC22pre-mRNA-splicing factor CWC22 homolog. (897 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (738 aa)
SF3B3Splicing factor 3B subunit 3. (1216 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (284 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (125 aa)
ENSEEUP00000014016annotation not available (314 aa)
PLRG1Pleiotropic regulator 1. (502 aa)
ZCCHC8Zinc finger CCHC domain-containing protein 8. (710 aa)
SYF2pre-mRNA-splicing factor SYF2. (183 aa)
ENSEEUP00000013630annotation not available (102 aa)
ENSEEUP00000013081annotation not available (358 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component. (881 aa)
CWC27Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1. (472 aa)
ENSEEUP00000011134annotation not available (2333 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2018 aa)
ENSEEUP00000011279annotation not available (475 aa)
GPATCH1G-patch domain containing 1. (930 aa)
SNRPFSmall nuclear ribonucleoprotein F. (85 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'. (225 aa)
SRRM1Serine/arginine repetitive matrix protein 1 isoform X1. (912 aa)
ENSEEUP00000012819annotation not available (126 aa)
SRRM2Serine/arginine repetitive matrix protein 2 isoform X1. (2615 aa)
ENSEEUP00000013058annotation not available (891 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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