STRINGSTRING
TPM3 TPM3 FILIP1 FILIP1 MYL6B MYL6B MYL6 MYL6 TMOD4 TMOD4 ENSEEUP00000000367 ENSEEUP00000000367 MYH11 MYH11 SMTN SMTN ENSEEUP00000000600 ENSEEUP00000000600 FMN1 FMN1 ENSEEUP00000000755 ENSEEUP00000000755 BICD2 BICD2 IQGAP3 IQGAP3 HCLS1 HCLS1 UBR7 UBR7 NEXN NEXN LOC103124118 LOC103124118 CD2AP CD2AP APMAP APMAP BMF BMF ENSEEUP00000001360 ENSEEUP00000001360 PLS1 PLS1 MYO1D MYO1D ABL1 ABL1 DAAM2 DAAM2 MYL9 MYL9 CARMIL2 CARMIL2 DCTN3 DCTN3 ENSEEUP00000001805 ENSEEUP00000001805 SH3PXD2A SH3PXD2A MYO18A MYO18A FSCN2 FSCN2 RHOU RHOU ENSEEUP00000002708 ENSEEUP00000002708 MYO7A MYO7A ENSEEUP00000003029 ENSEEUP00000003029 XIRP2 XIRP2 ENSEEUP00000003182 ENSEEUP00000003182 SSMEM1 SSMEM1 DBNL DBNL SHROOM4 SHROOM4 SPATA17 SPATA17 AVIL AVIL COBL COBL ABLIM1 ABLIM1 MYO1H MYO1H ASAP1 ASAP1 ENSEEUP00000003987 ENSEEUP00000003987 MYH15 MYH15 LANCL2 LANCL2 FLNB FLNB ENSEEUP00000004580 ENSEEUP00000004580 MYL1 MYL1 LANCL3 LANCL3 WAS WAS ENSEEUP00000004985 ENSEEUP00000004985 LCP1 LCP1 PLEKHH2 PLEKHH2 GAS7 GAS7 ENSEEUP00000005495 ENSEEUP00000005495 OCM OCM MYH8 MYH8 LOC103113171 LOC103113171 DEF6 DEF6 FMN1-2 FMN1-2 ENSEEUP00000006064 ENSEEUP00000006064 SPTB SPTB ENSEEUP00000006158 ENSEEUP00000006158 LOC103110701 LOC103110701 KRT14 KRT14 SYNPO2 SYNPO2 KIF9 KIF9 DCTN6 DCTN6 ACTN2 ACTN2 BIN2 BIN2 ACTN1 ACTN1 NEBL NEBL SORBS1 SORBS1 CORO6-2 CORO6-2 CAPZA2 CAPZA2 ACTR2 ACTR2 ARPC5L ARPC5L FHL3 FHL3 ENSEEUP00000008703 ENSEEUP00000008703 TNNT2 TNNT2 DBN1 DBN1 ACTR10 ACTR10 DCTN4 DCTN4 CDC42BPB CDC42BPB PAICS PAICS TMOD3 TMOD3 ENSEEUP00000009589 ENSEEUP00000009589 LIMCH1 LIMCH1 TNNC2 TNNC2 RFLNB RFLNB ENSEEUP00000010035 ENSEEUP00000010035 CCDC88A CCDC88A RTKN RTKN AUH AUH ENSEEUP00000010397 ENSEEUP00000010397 ARPC5 ARPC5 LOC103110700 LOC103110700 GAS2 GAS2 ARPC3 ARPC3 TMOD2 TMOD2 ENSEEUP00000010758 ENSEEUP00000010758 DAAM1 DAAM1 ADD2 ADD2 WIPF1 WIPF1 FERMT3 FERMT3 MOK MOK ENSEEUP00000011767 ENSEEUP00000011767 ENSEEUP00000011896 ENSEEUP00000011896 CFL2 CFL2 ENSEEUP00000012366 ENSEEUP00000012366 ANLN ANLN SPTBN1 SPTBN1 MPRIP MPRIP ENSEEUP00000012659 ENSEEUP00000012659 PRRC2B PRRC2B CAPZA1 CAPZA1 HNRNPK HNRNPK MYO15A MYO15A WASL WASL P3H1 P3H1 ABL2 ABL2 ESPN ESPN CARMIL1 CARMIL1 ABLIM3 ABLIM3 ACTR3 ACTR3 CNN2 CNN2 RHOQ RHOQ DDX58 DDX58 PDLIM4 PDLIM4 AFAP1L1 AFAP1L1 DCTN5 DCTN5 FMN2 FMN2 GDPD2 GDPD2 GSN GSN AMOT AMOT KLHL2 KLHL2 SCIN SCIN ENSEEUP00000014534 ENSEEUP00000014534
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TPM3Tropomyosin alpha-3 chain isoform X2; Belongs to the tropomyosin family. (285 aa)
FILIP1filamin-A-interacting protein 1 isoform X1. (1213 aa)
MYL6BMyosin light chain 6B. (211 aa)
MYL6Myosin light polypeptide 6-like. (121 aa)
TMOD4Tropomodulin-4. (344 aa)
ENSEEUP00000000367annotation not available (671 aa)
MYH11Myosin-11 isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1857 aa)
SMTNSmoothelin isoform X1. (614 aa)
ENSEEUP00000000600annotation not available (696 aa)
FMN1Formin-1 isoform X2. (650 aa)
ENSEEUP00000000755annotation not available (275 aa)
BICD2Protein bicaudal D homolog 2 isoform X2. (826 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1629 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (472 aa)
UBR7Putative E3 ubiquitin-protein ligase UBR7. (300 aa)
NEXNNexilin. (664 aa)
LOC103124118Ankyrin repeat domain-containing protein 26-like. (1532 aa)
CD2APCD2-associated protein. (489 aa)
APMAPAdipocyte plasma membrane-associated protein. (315 aa)
BMFBcl-2-modifying factor. (184 aa)
ENSEEUP00000001360annotation not available (700 aa)
PLS1Plastin-1 isoform X1. (626 aa)
MYO1DUnconventional myosin-Id; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (904 aa)
ABL1Tyrosine-protein kinase. (925 aa)
DAAM2Disheveled-associated activator of morphogenesis 2 isoform X4. (1066 aa)
MYL9Myosin light chain 9. (115 aa)
CARMIL2F-actin-uncapping protein RLTPR. (1467 aa)
DCTN3Dynactin subunit 3 isoform X3. (137 aa)
ENSEEUP00000001805annotation not available (1108 aa)
SH3PXD2ASH3 and PX domain-containing protein 2A isoform X1. (841 aa)
MYO18AUnconventional myosin-XVIIIa isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2055 aa)
FSCN2Fascin. (491 aa)
RHOURas homolog family member U. (255 aa)
ENSEEUP00000002708annotation not available (808 aa)
MYO7AUnconventional myosin-VIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2199 aa)
ENSEEUP00000003029annotation not available (145 aa)
XIRP2Xin actin binding repeat containing 2. (3291 aa)
ENSEEUP00000003182annotation not available (524 aa)
SSMEM1Serine-rich single-pass membrane protein 1. (241 aa)
DBNLDrebrin-like protein isoform X3. (360 aa)
SHROOM4Protein Shroom4. (1461 aa)
SPATA17Spermatogenesis-associated protein 17. (313 aa)
AVILAdvillin. (782 aa)
COBLProtein cordon-bleu. (720 aa)
ABLIM1Actin binding LIM protein 1. (782 aa)
MYO1HUnconventional myosin-Ih; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (69 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1122 aa)
ENSEEUP00000003987annotation not available (367 aa)
MYH15LOW QUALITY PROTEIN: myosin-15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1944 aa)
LANCL2LOW QUALITY PROTEIN: lanC-like protein 2. (447 aa)
FLNBfilamin-B isoform X2. (2597 aa)
ENSEEUP00000004580annotation not available (624 aa)
MYL1Myosin light chain 1. (190 aa)
LANCL3lanC-like protein 3. (229 aa)
WASwiskott-Aldrich syndrome protein. (503 aa)
ENSEEUP00000004985annotation not available (744 aa)
LCP1Plastin-2 isoform X1. (627 aa)
PLEKHH2Pleckstrin homology domain-containing family H member 2. (1370 aa)
GAS7Growth arrest-specific protein 7 isoform X1. (473 aa)
ENSEEUP00000005495annotation not available (194 aa)
OCMOncomodulin-1; Belongs to the parvalbumin family. (101 aa)
MYH8Myosin heavy chain 8. (1932 aa)
LOC103113171Myosin-4 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
DEF6Differentially expressed in FDCP 6 homolog. (631 aa)
FMN1-2Formin-1 isoform X3. (845 aa)
ENSEEUP00000006064annotation not available (310 aa)
SPTBSpectrin beta, erythrocytic. (2262 aa)
ENSEEUP00000006158annotation not available (1939 aa)
LOC103110701Myosin regulatory light chain 12B. (172 aa)
KRT14Keratin, type I cytoskeletal 14; Belongs to the intermediate filament family. (469 aa)
SYNPO2Synaptopodin-2. (1250 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (787 aa)
DCTN6Dynactin subunit 6. (159 aa)
ACTN2Alpha-actinin-2 isoform X4. (747 aa)
BIN2Bridging integrator 2-like. (553 aa)
ACTN1Alpha-actinin-1 isoform X2. (857 aa)
NEBLNebulette isoform X1. (978 aa)
SORBS1Sorbin and SH3 domain-containing protein 2 isoform X5. (1291 aa)
CORO6-2Coronin-6 isoform X2. (474 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (284 aa)
ACTR2Actin related protein 2. (399 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
FHL3Four and a half LIM domains protein 3 isoform X1. (229 aa)
ENSEEUP00000008703annotation not available (597 aa)
TNNT2Troponin T, cardiac muscle. (270 aa)
DBN1Drebrin 1. (635 aa)
ACTR10Actin-related protein 10; Belongs to the actin family. (332 aa)
DCTN4Dynactin subunit 4 isoform X2. (460 aa)
CDC42BPBSerine/threonine-protein kinase MRCK beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1603 aa)
PAICSMultifunctional protein ADE2. (417 aa)
TMOD3Tropomodulin-3. (352 aa)
ENSEEUP00000009589annotation not available (527 aa)
LIMCH1LIM and calponin homology domains 1. (1457 aa)
TNNC2Troponin C, skeletal muscle. (160 aa)
RFLNBFilamin-interacting protein FAM101B. (146 aa)
ENSEEUP00000010035annotation not available (1009 aa)
CCDC88AGirdin. (1864 aa)
RTKNRhotekin isoform X2. (564 aa)
AUHmethylglutaconyl-CoA hydratase, mitochondrial isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family. (336 aa)
ENSEEUP00000010397annotation not available (979 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (148 aa)
LOC103110700Myosin regulatory light chain 12B-like isoform X1. (172 aa)
GAS2Growth arrest specific 2. (307 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (176 aa)
TMOD2Tropomodulin-2 isoform X1. (254 aa)
ENSEEUP00000010758annotation not available (773 aa)
DAAM1Disheveled-associated activator of morphogenesis 1 isoform X1. (1073 aa)
ADD2Beta-adducin. (725 aa)
WIPF1WAS/WASL-interacting protein family member 1. (483 aa)
FERMT3Fermitin family member 3. (664 aa)
MOKMAPK/MAK/MRK overlapping kinase; Belongs to the protein kinase superfamily. (375 aa)
ENSEEUP00000011767annotation not available (811 aa)
ENSEEUP00000011896annotation not available (756 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (165 aa)
ENSEEUP00000012366annotation not available (623 aa)
ANLNActin-binding protein anillin isoform X1. (1117 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2358 aa)
MPRIPMyosin phosphatase Rho-interacting protein isoform X3. (1375 aa)
ENSEEUP00000012659annotation not available (1162 aa)
PRRC2BProtein PRRC2B isoform X6. (1266 aa)
CAPZA1Capping actin protein of muscle Z-line subunit alpha 1. (286 aa)
HNRNPKHeterogeneous nuclear ribonucleoprotein K isoform X1. (464 aa)
MYO15AMyosin XVA. (3496 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
P3H1Prolyl 3-hydroxylase 1 isoform X2. (406 aa)
ABL2Tyrosine-protein kinase. (1183 aa)
ESPNEspin isoform X1. (639 aa)
CARMIL1F-actin-uncapping protein LRRC16A isoform X2. (1369 aa)
ABLIM3Actin binding LIM protein family member 3. (676 aa)
ACTR3Actin-related protein 3 isoform X2; Belongs to the actin family. (343 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (172 aa)
RHOQRho-related GTP-binding protein RhoQ. (157 aa)
DDX58Probable ATP-dependent RNA helicase DDX58. (923 aa)
PDLIM4PDZ and LIM domain protein 4 isoform X1. (332 aa)
AFAP1L1Actin filament-associated protein 1-like 1. (764 aa)
DCTN5Dynactin subunit 5. (182 aa)
FMN2Formin-2. (1116 aa)
GDPD2Glycerophosphoinositol inositolphosphodiesterase GDPD2. (541 aa)
GSNGelsolin isoform X1. (774 aa)
AMOTAngiomotin. (1073 aa)
KLHL2Kelch-like protein 2. (543 aa)
SCINAdseverin. (532 aa)
ENSEEUP00000014534annotation not available (359 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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