60 items (Erinaceus europaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRMT13	tRNA methyltransferase 13 homolog. (474 aa)
	CD2BP2	CD2 cytoplasmic tail binding protein 2. (343 aa)
	DDX20	Probable ATP-dependent RNA helicase DDX20. (483 aa)
	CHODL	Chondrolectin isoform X1. (273 aa)
	SF3B1	Splicing factor 3B subunit 1 isoform X1. (1299 aa)
	RBMX2	RNA-binding motif protein, X-linked 2 isoform X1. (211 aa)
	TSNAX	Translin-associated protein X. (288 aa)
	ENSEEUP00000001752	annotation not available (65 aa)
	LSM6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (78 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (183 aa)
	SART3	Squamous cell carcinoma antigen recognized by T-cells 3 isoform X2. (965 aa)
	SF3A1	Splicing factor 3A subunit 1. (701 aa)
	ENSEEUP00000003510	annotation not available (586 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (60 aa)
	SNRPA1	LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein A. (254 aa)
	ENSEEUP00000004107	annotation not available (63 aa)
	ENSEEUP00000004418	annotation not available (383 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (89 aa)
	LOC103126981	UPF0692 protein C19orf54 homolog. (179 aa)
	PPIH	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (175 aa)
	SNRNP70	U1 small nuclear ribonucleoprotein 70 kDa. (437 aa)
	ENSEEUP00000005228	annotation not available (95 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
	GEMIN4	Gem-associated protein 4. (1059 aa)
	SNRPG	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
	PRPF40B	pre-mRNA-processing factor 40 homolog B isoform X3. (772 aa)
	PPP1R8	Nuclear inhibitor of protein phosphatase 1 isoform X1. (351 aa)
	PRPF3	U4/U6 small nuclear ribonucleoprotein Prp3. (681 aa)
	LOC103123420	Small nuclear ribonucleoprotein-associated protein. (239 aa)
	PRPF4	pre-mRNA processing factor 4. (458 aa)
	ENSEEUP00000007143	annotation not available (188 aa)
	STRAP	Serine-threonine kinase receptor-associated protein. (350 aa)
	USP39	U4/U6.U5 tri-snRNP-associated protein 2 isoform X1. (563 aa)
	GEMIN2	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (278 aa)
	PDE6C	Phosphodiesterase. (827 aa)
	TXNL4A	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (91 aa)
	DDX23	Probable ATP-dependent RNA helicase DDX23. (822 aa)
	HTATSF1	HIV Tat-specific factor 1. (761 aa)
	CLNS1A	Methylosome subunit pICln. (214 aa)
	LSM11	U7 snRNA-associated Sm-like protein LSm11. (210 aa)
	ZNF608	Zinc finger protein 608 isoform X1. (1371 aa)
	ENSEEUP00000010964	annotation not available (313 aa)
	ENSEEUP00000011134	annotation not available (2333 aa)
	GEMIN5	Gem-associated protein 5. (1436 aa)
	SNRNP200	U5 small nuclear ribonucleoprotein 200 kDa helicase. (2018 aa)
	RNPC3	RNA-binding protein 40 isoform X1. (64 aa)
	SNRPF	Small nuclear ribonucleoprotein F. (85 aa)
	SNRPB2	U2 small nuclear ribonucleoprotein B'. (225 aa)
	ENSEEUP00000012819	annotation not available (126 aa)
	ENSEEUP00000013058	annotation not available (891 aa)
	CCDC84	Coiled-coil domain-containing protein 84. (333 aa)
	ENSEEUP00000013630	annotation not available (102 aa)
	DDX39A	ATP-dependent RNA helicase DDX39A. (422 aa)
	SNRPA	U1 small nuclear ribonucleoprotein A isoform X1. (282 aa)
	C3orf49	Uncharacterized protein. (282 aa)
	GEMIN8	Gem-associated protein 8. (308 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (125 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (284 aa)
	SMN1	Survival motor neuron protein. (248 aa)
	ENSEEUP00000014593	annotation not available (1803 aa)

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC84	PRPF3	ENSEEUP00000013222	ENSEEUP00000006712	Coiled-coil domain-containing protein 84.	U4/U6 small nuclear ribonucleoprotein Prp3.	0.581
CCDC84	SNRPE	ENSEEUP00000013222	ENSEEUP00000005629	Coiled-coil domain-containing protein 84.	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.	0.414
CCDC84	TXNL4A	ENSEEUP00000013222	ENSEEUP00000008246	Coiled-coil domain-containing protein 84.	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.	0.540
CD2BP2	DDX23	ENSEEUP00000000412	ENSEEUP00000008818	CD2 cytoplasmic tail binding protein 2.	Probable ATP-dependent RNA helicase DDX23.	0.962
CD2BP2	ENSEEUP00000004107	ENSEEUP00000000412	ENSEEUP00000004107	CD2 cytoplasmic tail binding protein 2.	annotation not available	0.527
CD2BP2	ENSEEUP00000007143	ENSEEUP00000000412	ENSEEUP00000007143	CD2 cytoplasmic tail binding protein 2.	annotation not available	0.844
CD2BP2	ENSEEUP00000011134	ENSEEUP00000000412	ENSEEUP00000011134	CD2 cytoplasmic tail binding protein 2.	annotation not available	0.953
CD2BP2	ENSEEUP00000012819	ENSEEUP00000000412	ENSEEUP00000012819	CD2 cytoplasmic tail binding protein 2.	annotation not available	0.461
CD2BP2	ENSEEUP00000013630	ENSEEUP00000000412	ENSEEUP00000013630	CD2 cytoplasmic tail binding protein 2.	annotation not available	0.463
CD2BP2	LOC103123420	ENSEEUP00000000412	ENSEEUP00000006755	CD2 cytoplasmic tail binding protein 2.	Small nuclear ribonucleoprotein-associated protein.	0.844
CD2BP2	PRPF3	ENSEEUP00000000412	ENSEEUP00000006712	CD2 cytoplasmic tail binding protein 2.	U4/U6 small nuclear ribonucleoprotein Prp3.	0.786
CD2BP2	PRPF4	ENSEEUP00000000412	ENSEEUP00000006833	CD2 cytoplasmic tail binding protein 2.	pre-mRNA processing factor 4.	0.407
CD2BP2	SNRNP200	ENSEEUP00000000412	ENSEEUP00000011188	CD2 cytoplasmic tail binding protein 2.	U5 small nuclear ribonucleoprotein 200 kDa helicase.	0.980
CD2BP2	SNRPA	ENSEEUP00000000412	ENSEEUP00000013817	CD2 cytoplasmic tail binding protein 2.	U1 small nuclear ribonucleoprotein A isoform X1.	0.545
CD2BP2	SNRPD1	ENSEEUP00000000412	ENSEEUP00000004528	CD2 cytoplasmic tail binding protein 2.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.628
CD2BP2	SNRPE	ENSEEUP00000000412	ENSEEUP00000005629	CD2 cytoplasmic tail binding protein 2.	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.	0.631
CD2BP2	SNRPF	ENSEEUP00000000412	ENSEEUP00000012303	CD2 cytoplasmic tail binding protein 2.	Small nuclear ribonucleoprotein F.	0.741
CD2BP2	TXNL4A	ENSEEUP00000000412	ENSEEUP00000008246	CD2 cytoplasmic tail binding protein 2.	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.	0.938
CD2BP2	USP39	ENSEEUP00000000412	ENSEEUP00000007452	CD2 cytoplasmic tail binding protein 2.	U4/U6.U5 tri-snRNP-associated protein 2 isoform X1.	0.653
CLNS1A	DDX20	ENSEEUP00000009730	ENSEEUP00000000427	Methylosome subunit pICln.	Probable ATP-dependent RNA helicase DDX20.	0.512