STRINGSTRING
ABCF1 ABCF1 ABCC2 ABCC2 KATNAL2 KATNAL2 SPG7 SPG7 CDC6 CDC6 ABCC1 ABCC1 DNAH5 DNAH5 CLPB CLPB LONP2 LONP2 DMC1 DMC1 GPN1 GPN1 RFC5 RFC5 BCS1L BCS1L ABCC8 ABCC8 ABCA12 ABCA12 DNAH6 DNAH6 ORC1 ORC1 RUVBL1 RUVBL1 WRNIP1 WRNIP1 ABCG2 ABCG2 DNAH11 DNAH11 VWA8 VWA8 TAP2 TAP2 ABCG5 ABCG5 ABCA4 ABCA4 ABCB4 ABCB4 PEX6 PEX6 ASCC3 ASCC3 ABCE1 ABCE1 FIGNL1 FIGNL1 DNAH8 DNAH8 DNAH3 DNAH3 TRIP13 TRIP13 VPS4B VPS4B PSMC4 PSMC4 AFG3L2 AFG3L2 ATAD2 ATAD2 PSMC3 PSMC3 DYNC1H1 DYNC1H1 YME1L1 YME1L1 ABCA13 ABCA13 RAD51B RAD51B RAD51D RAD51D SRP54 SRP54 FIGN FIGN ABCC6 ABCC6 PEX1 PEX1 ABCA5 ABCA5 ATP5F1B ATP5F1B DNAH10 DNAH10 ATAD2B ATAD2B ABCC10 ABCC10 LOC103127808 LOC103127808 CLPX CLPX ABCC9 ABCC9 LOC103107789 LOC103107789 ATAD3A ATAD3A PSMC1 PSMC1 PSMC2 PSMC2 ABCD3 ABCD3 ABCA8 ABCA8 HELZ2 HELZ2 ABCC4 ABCC4 MCM3 MCM3 ABCB11 ABCB11 TAP1 TAP1 NTPCR NTPCR AK9 AK9 ABCC12 ABCC12 ABCC11 ABCC11 ABCF3 ABCF3 CFTR CFTR DNAH9 DNAH9 MCM8 MCM8 ATAD1 ATAD1 NAV2 NAV2 RNF213 RNF213 ABCA2 ABCA2 KATNAL1 KATNAL1 ABCG4 ABCG4 DNAH12 DNAH12 ABCB5 ABCB5 ABCB6 ABCB6 LOC103121233 LOC103121233 ABCB10 ABCB10 SRPRA SRPRA ABCB9 ABCB9 VPS4A VPS4A RFC4 RFC4 ABCA1 ABCA1 NSF NSF LOC103107788 LOC103107788 RFC3 RFC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCF1ATP-binding cassette sub-family F member 1 isoform X1. (841 aa)
ABCC2Canalicular multispecific organic anion transporter 1. (1524 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (388 aa)
SPG7Paraplegin isoform X1. (789 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (553 aa)
ABCC1Multidrug resistance-associated protein 1. (1513 aa)
DNAH5Dynein heavy chain 5, axonemal. (4615 aa)
CLPBCaseinolytic peptidase B protein homolog isoform X3. (554 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (843 aa)
DMC1Meiotic recombination protein DMC1/LIM15 homolog isoform X1; Belongs to the RecA family. (323 aa)
GPN1GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (378 aa)
RFC5Replication factor C subunit 5. (304 aa)
BCS1LMitochondrial chaperone BCS1 isoform X1; Belongs to the AAA ATPase family. (417 aa)
ABCC8ATP-binding cassette sub-family C member 8 isoform X1. (1564 aa)
ABCA12ATP-binding cassette sub-family A member 12. (2595 aa)
DNAH6Dynein heavy chain 6, axonemal. (1331 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (797 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (338 aa)
WRNIP1ATPase WRNIP1 isoform X1. (533 aa)
ABCG2ATP-binding cassette sub-family G member 2-like. (655 aa)
DNAH11Dynein heavy chain 11, axonemal. (4336 aa)
VWA8Von Willebrand factor A domain-containing protein 8. (1853 aa)
TAP2Antigen peptide transporter 2. (622 aa)
ABCG5ATP-binding cassette sub-family G member 5. (545 aa)
ABCA4Retinal-specific ATP-binding cassette transporter. (2279 aa)
ABCB4Phosphatidylcholine translocator ABCB4. (1206 aa)
PEX6Peroxisome biogenesis factor 6 isoform X1. (828 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (1933 aa)
ABCE1ATP-binding cassette sub-family E member 1. (503 aa)
FIGNL1Fidgetin-like protein 1; Belongs to the AAA ATPase family. (677 aa)
DNAH8Dynein heavy chain 8, axonemal. (4692 aa)
DNAH3Dynein heavy chain 3, axonemal. (4070 aa)
TRIP13Pachytene checkpoint protein 2 homolog; Belongs to the AAA ATPase family. (278 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (398 aa)
PSMC426S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (414 aa)
AFG3L2AFG3-like protein 2. (760 aa)
ATAD2ATPase family AAA domain-containing protein 2. (1350 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (438 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (4557 aa)
YME1L1ATP-dependent zinc metalloprotease YME1L1 isoform X1. (714 aa)
ABCA13LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 13. (4994 aa)
RAD51BDNA repair protein RAD51 homolog 2. (344 aa)
RAD51DDNA repair protein RAD51 homolog 4 isoform X1. (327 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (503 aa)
FIGNFidgetin; Belongs to the AAA ATPase family. (639 aa)
ABCC6Multidrug resistance-associated protein 6. (84 aa)
PEX1Peroxisome biogenesis factor 1 isoform X1. (1254 aa)
ABCA5ATP-binding cassette sub-family A member 5. (1633 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (495 aa)
DNAH10Dynein heavy chain 10, axonemal. (1425 aa)
ATAD2BATPase family AAA domain-containing protein 2B. (733 aa)
ABCC10Multidrug resistance-associated protein 7. (1491 aa)
LOC103127808Spastin; Belongs to the AAA ATPase family. (509 aa)
CLPXATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. (521 aa)
ABCC9ATP-binding cassette sub-family C member 9. (1545 aa)
LOC103107789ATP-binding cassette sub-family A member 3-like. (101 aa)
ATAD3AATPase family AAA domain-containing protein 3A isoform X2. (585 aa)
PSMC126S protease regulatory subunit 4 isoform X2; Belongs to the AAA ATPase family. (439 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
ABCD3ATP-binding cassette sub-family D member 3 isoform X3. (460 aa)
ABCA8ATP-binding cassette sub-family A member 8-like. (1543 aa)
HELZ2Helicase with zinc finger domain 2 isoform X1. (2442 aa)
ABCC4Multidrug resistance-associated protein 4 isoform X1. (1320 aa)
MCM3DNA helicase; Belongs to the MCM family. (788 aa)
ABCB11Bile salt export pump isoform X2. (1324 aa)
TAP1Antigen peptide transporter 1. (550 aa)
NTPCRCancer-related nucleoside-triphosphatase. (168 aa)
AK9Adenylate kinase 9. (254 aa)
ABCC12Multidrug resistance-associated protein 9. (1357 aa)
ABCC11ATP-binding cassette sub-family C member 11. (1331 aa)
ABCF3ATP-binding cassette sub-family F member 3 isoform X1. (709 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
DNAH9Dynein heavy chain 9, axonemal. (101 aa)
MCM8DNA helicase MCM8 isoform X1; Belongs to the MCM family. (822 aa)
ATAD1ATPase family AAA domain-containing protein 1 isoform X1; Belongs to the AAA ATPase family. (361 aa)
NAV2Neuron navigator 2 isoform X1. (2467 aa)
RNF213E3 ubiquitin-protein ligase RNF213 isoform X1. (3134 aa)
ABCA2ATP-binding cassette sub-family A member 2. (2244 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
ABCG4ATP-binding cassette sub-family G member 4. (546 aa)
DNAH12LOW QUALITY PROTEIN: dynein heavy chain 12, axonemal. (190 aa)
ABCB5ATP-binding cassette sub-family B member 5. (831 aa)
ABCB6ATP-binding cassette sub-family B member 6, mitochondrial. (887 aa)
LOC103121233AFG3-like protein 1. (772 aa)
ABCB10ATP-binding cassette sub-family B member 10, mitochondrial. (727 aa)
SRPRASignal recognition particle receptor subunit alpha isoform X1. (638 aa)
ABCB9ATP-binding cassette sub-family B member 9. (653 aa)
VPS4AVacuolar protein sorting-associated protein 4A isoform X1; Belongs to the AAA ATPase family. (430 aa)
RFC4Replication factor C subunit 4. (363 aa)
ABCA1ATP-binding cassette sub-family A member 1. (2258 aa)
NSFVesicle-fusing ATPase isoform X1. (736 aa)
LOC103107788ATP-binding cassette sub-family A member 3-like. (108 aa)
RFC3Replication factor C subunit 3. (353 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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