16 items (Erinaceus europaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103123420	Small nuclear ribonucleoprotein-associated protein. (239 aa)
	ATXN2L	Ataxin-2-like protein isoform X1. (940 aa)
	LSM11	U7 snRNA-associated Sm-like protein LSm11. (210 aa)
	LSM10	U7 snRNA-associated Sm-like protein LSm10 isoform X1. (123 aa)
	SNRPF	Small nuclear ribonucleoprotein F. (85 aa)
	ATXN2	Ataxin-2. (1069 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (99 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (125 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (284 aa)
	LSM14A	Protein LSM14 homolog A isoform X1. (456 aa)
	LSM12	Protein LSM12 homolog. (153 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (60 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (89 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
	SNRPG	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
	LSM14B	Protein LSM14 homolog B. (285 aa)

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN2	ATXN2L	ENSEEUP00000013384	ENSEEUP00000008182	Ataxin-2.	Ataxin-2-like protein isoform X1.	0.900
ATXN2	LOC103123420	ENSEEUP00000013384	ENSEEUP00000006755	Ataxin-2.	Small nuclear ribonucleoprotein-associated protein.	0.802
ATXN2	LSM12	ENSEEUP00000013384	ENSEEUP00000002204	Ataxin-2.	Protein LSM12 homolog.	0.979
ATXN2	LSM14A	ENSEEUP00000013384	ENSEEUP00000014334	Ataxin-2.	Protein LSM14 homolog A isoform X1.	0.462
ATXN2L	ATXN2	ENSEEUP00000008182	ENSEEUP00000013384	Ataxin-2-like protein isoform X1.	Ataxin-2.	0.900
ATXN2L	LOC103123420	ENSEEUP00000008182	ENSEEUP00000006755	Ataxin-2-like protein isoform X1.	Small nuclear ribonucleoprotein-associated protein.	0.802
ATXN2L	LSM12	ENSEEUP00000008182	ENSEEUP00000002204	Ataxin-2-like protein isoform X1.	Protein LSM12 homolog.	0.969
ATXN2L	LSM14A	ENSEEUP00000008182	ENSEEUP00000014334	Ataxin-2-like protein isoform X1.	Protein LSM14 homolog A isoform X1.	0.631
ATXN2L	LSM14B	ENSEEUP00000008182	ENSEEUP00000006663	Ataxin-2-like protein isoform X1.	Protein LSM14 homolog B.	0.569
LOC103123420	ATXN2	ENSEEUP00000006755	ENSEEUP00000013384	Small nuclear ribonucleoprotein-associated protein.	Ataxin-2.	0.802
LOC103123420	ATXN2L	ENSEEUP00000006755	ENSEEUP00000008182	Small nuclear ribonucleoprotein-associated protein.	Ataxin-2-like protein isoform X1.	0.802
LOC103123420	LSM1	ENSEEUP00000006755	ENSEEUP00000013851	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.	0.436
LOC103123420	LSM10	ENSEEUP00000006755	ENSEEUP00000010947	Small nuclear ribonucleoprotein-associated protein.	U7 snRNA-associated Sm-like protein LSm10 isoform X1.	0.937
LOC103123420	LSM11	ENSEEUP00000006755	ENSEEUP00000009826	Small nuclear ribonucleoprotein-associated protein.	U7 snRNA-associated Sm-like protein LSm11.	0.760
LOC103123420	LSM12	ENSEEUP00000006755	ENSEEUP00000002204	Small nuclear ribonucleoprotein-associated protein.	Protein LSM12 homolog.	0.464
LOC103123420	LSM5	ENSEEUP00000006755	ENSEEUP00000003706	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.922
LOC103123420	SNRPD1	ENSEEUP00000006755	ENSEEUP00000004528	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.975
LOC103123420	SNRPD3	ENSEEUP00000006755	ENSEEUP00000014155	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.	0.978
LOC103123420	SNRPE	ENSEEUP00000006755	ENSEEUP00000005629	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.	0.980
LOC103123420	SNRPF	ENSEEUP00000006755	ENSEEUP00000012303	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein F.	0.979