STRINGSTRING
CLP1 CLP1 NCBP1 NCBP1 SNRPB SNRPB SNRPD3 SNRPD3 CPSF3 CPSF3 CSTF3 CSTF3 CPSF6 CPSF6 ENSEEUP00000013301 ENSEEUP00000013301 PAPOLA PAPOLA SNRPF SNRPF ENSEEUP00000000236 ENSEEUP00000000236 CPSF1 CPSF1 ENSEEUP00000001752 ENSEEUP00000001752 CPSF4 CPSF4 ENSEEUP00000002309 ENSEEUP00000002309 NUDT21 NUDT21 ENSEEUP00000003881 ENSEEUP00000003881 WDR33 WDR33 NCBP2L NCBP2L FIP1L1 FIP1L1 CPSF7 CPSF7 SNRPE SNRPE PCF11 PCF11 SNRPG SNRPG ZNF473 ZNF473 ENSEEUP00000006787 ENSEEUP00000006787 ENSEEUP00000007202 ENSEEUP00000007202 CSTF1 CSTF1 LSM11 LSM11 LSM10 LSM10 LOC103125758 LOC103125758
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
NCBP1Nuclear cap-binding protein subunit 1. (747 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (284 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (125 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3. (683 aa)
CSTF3Cleavage stimulation factor subunit 3. (717 aa)
CPSF6Cleavage and polyadenylation specificity factor subunit 6 isoform X1. (568 aa)
ENSEEUP00000013301annotation not available (431 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (705 aa)
SNRPFSmall nuclear ribonucleoprotein F. (85 aa)
ENSEEUP00000000236annotation not available (1083 aa)
CPSF1Cleavage and polyadenylation specificity factor subunit 1. (1445 aa)
ENSEEUP00000001752annotation not available (65 aa)
CPSF4Cleavage and polyadenylation specificity factor subunit 4 isoform X2. (234 aa)
ENSEEUP00000002309annotation not available (203 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
ENSEEUP00000003881annotation not available (189 aa)
WDR33WD repeat domain 33. (1207 aa)
NCBP2LNuclear cap binding protein subunit 2 like. (152 aa)
FIP1L1pre-mRNA 3'-end-processing factor FIP1 isoform X1. (561 aa)
CPSF7Cleavage and polyadenylation specificity factor subunit 7 isoform X1. (399 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
PCF11pre-mRNA cleavage complex 2 protein Pcf11 isoform X2. (1652 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
ZNF473Zinc finger protein 473. (865 aa)
ENSEEUP00000006787annotation not available (781 aa)
ENSEEUP00000007202annotation not available (431 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
LSM11U7 snRNA-associated Sm-like protein LSm11. (210 aa)
LSM10U7 snRNA-associated Sm-like protein LSm10 isoform X1. (123 aa)
LOC103125758Polyadenylate-binding protein 2 isoform X1. (293 aa)
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.