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HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (470 aa) | ||||
CDC23 | Cell division cycle 23. (591 aa) | ||||
CDC45 | Cell division control protein 45 homolog. (481 aa) | ||||
CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
CDC26 | Anaphase-promoting complex subunit CDC26. (58 aa) | ||||
STAG2 | Cohesin subunit SA-2. (1268 aa) | ||||
MCM7 | Minichromosome maintenance complex component 7. (682 aa) | ||||
SMAD2 | Mothers against decapentaplegic homolog. (426 aa) | ||||
PRKDC | DNA-dependent protein kinase catalytic subunit. (4126 aa) | ||||
CDK1 | Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (284 aa) | ||||
ORC5 | Origin recognition complex subunit 5. (420 aa) | ||||
CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (138 aa) | ||||
ENSEEUP00000010564 | annotation not available (560 aa) | ||||
TMEM82 | Transmembrane protein 82. (305 aa) | ||||
CDC14A | Dual specificity protein phosphatase CDC14A. (579 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3041 aa) | ||||
CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (121 aa) | ||||
CDC25A | M-phase inducer phosphatase 1. (509 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (829 aa) | ||||
ZNF652 | Zinc finger protein 652. (608 aa) | ||||
RBL2 | Retinoblastoma-like protein 2 isoform X2. (1136 aa) | ||||
GSK3B | Glycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (433 aa) | ||||
ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) | ||||
CDC27 | Cell division cycle protein 27 homolog. (785 aa) | ||||
CDC7 | Cell division cycle 7-related protein kinase. (483 aa) | ||||
AP5S1 | AP-5 complex subunit sigma-1. (141 aa) | ||||
ENSEEUP00000008599 | annotation not available (323 aa) | ||||
EP300 | Histone acetyltransferase p300. (1983 aa) | ||||
ORC2 | Origin recognition complex subunit 2. (548 aa) | ||||
MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A. (196 aa) | ||||
RBL1 | Retinoblastoma-like protein 1. (876 aa) | ||||
YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) | ||||
CCNB1 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (394 aa) | ||||
DBF4 | Protein DBF4 homolog A. (514 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (788 aa) | ||||
ENSEEUP00000004580 | annotation not available (624 aa) | ||||
ZBTB46 | Zinc finger and BTB domain-containing protein 46. (405 aa) | ||||
ENSEEUP00000004369 | annotation not available (1233 aa) | ||||
MYNN | Myoneurin. (519 aa) | ||||
CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (226 aa) | ||||
CHEK1 | Serine/threonine-protein kinase Chk1 isoform X1; Belongs to the protein kinase superfamily. (476 aa) | ||||
ORC3 | Origin recognition complex subunit 3. (712 aa) | ||||
PCNA | Proliferating cell nuclear antigen. (259 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (820 aa) | ||||
ENSEEUP00000002529 | annotation not available (468 aa) | ||||
CDC25C | M-phase inducer phosphatase 3 isoform X2. (418 aa) | ||||
ENSEEUP00000002216 | annotation not available (543 aa) | ||||
CCNE2 | G1/S-specific cyclin-E2 isoform X2; Belongs to the cyclin family. (403 aa) | ||||
ENSEEUP00000001618 | annotation not available (457 aa) | ||||
ABL1 | Tyrosine-protein kinase. (925 aa) | ||||
CCNA1 | cyclin-A1; Belongs to the cyclin family. (413 aa) | ||||
ENSEEUP00000000492 | annotation not available (46 aa) | ||||
SMAD4 | Mothers against decapentaplegic homolog. (551 aa) | ||||
SKP2 | S-phase kinase-associated protein 2 isoform X2. (314 aa) | ||||
ENSEEUP00000001332 | annotation not available (113 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) | ||||
RAD21 | Double-strand-break repair protein rad21 homolog. (631 aa) | ||||
ENSEEUP00000001281 | annotation not available (392 aa) | ||||
ENSEEUP00000001196 | annotation not available (240 aa) | ||||
CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) | ||||
ENSEEUP00000001146 | annotation not available (493 aa) | ||||
ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) | ||||
CCNB2 | G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (362 aa) | ||||
ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (123 aa) | ||||
ESPL1 | Separin. (2102 aa) | ||||
ANAPC2 | Anaphase promoting complex subunit 2. (818 aa) | ||||
ENSEEUP00000000751 | annotation not available (1259 aa) | ||||
STAG1 | Cohesin subunit SA-1 isoform X1. (1257 aa) | ||||
ENSEEUP00000010893 | annotation not available (47 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (440 aa) | ||||
SMC1B | Structural maintenance of chromosomes protein 1B. (1204 aa) | ||||
ATR | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2572 aa) | ||||
CDKN1A | Cyclin-dependent kinase inhibitor 1. (159 aa) | ||||
CDK3 | Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (304 aa) | ||||
ORC6 | Origin recognition complex subunit 6. (252 aa) | ||||
ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (797 aa) | ||||
ZBTB10 | Zinc finger and BTB domain-containing protein 10 isoform X2. (776 aa) | ||||
CDC25B | M-phase inducer phosphatase 2 isoform X1. (601 aa) | ||||
ENSEEUP00000011702 | annotation not available (224 aa) | ||||
ENSEEUP00000011815 | annotation not available (1943 aa) | ||||
SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (133 aa) | ||||
PTTG1 | Securin isoform X1. (201 aa) | ||||
E2F2 | Transcription factor E2F2. (431 aa) | ||||
GADD45G | Growth arrest and DNA damage inducible gamma. (94 aa) | ||||
BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1043 aa) | ||||
CDK7 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (246 aa) | ||||
CCNA2 | cyclin-A2; Belongs to the cyclin family. (256 aa) | ||||
TTK | Dual specificity protein kinase TTK. (772 aa) | ||||
CDKN1B | Cyclin-dependent kinase inhibitor 1B. (197 aa) | ||||
SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (47 aa) | ||||
CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa) | ||||
CDK2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) | ||||
E2F4 | Transcription factor E2F4 isoform X1. (409 aa) | ||||
PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1; Belongs to the protein kinase superfamily. (493 aa) | ||||
E2F5 | Transcription factor E2F5. (269 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa) | ||||
FAM126B | Protein FAM126B isoform X2. (525 aa) | ||||
ENSEEUP00000013426 | annotation not available (47 aa) | ||||
CDK20 | Cyclin-dependent kinase 20 isoform X4; Belongs to the protein kinase superfamily. (235 aa) | ||||
MCM2 | DNA helicase; Belongs to the MCM family. (536 aa) | ||||
HDAC3 | Histone deacetylase 3 isoform X2. (353 aa) | ||||
ENSEEUP00000013640 | annotation not available (750 aa) | ||||
ENSEEUP00000014174 | annotation not available (150 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (553 aa) | ||||
ENSEEUP00000014410 | annotation not available (414 aa) | ||||
CDC20 | Cell division cycle protein 20 homolog. (500 aa) | ||||
E2F1 | Transcription factor E2F1. (341 aa) | ||||
SMC3 | Structural maintenance of chromosomes protein 3. (1219 aa) | ||||
BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1. (1068 aa) | ||||
E2F3 | Transcription factor E2F3 isoform X1. (461 aa) | ||||
WEE1 | Wee1-like protein kinase. (380 aa) | ||||
CDC20B | Cell division cycle protein 20 homolog B. (484 aa) | ||||
RB1 | Retinoblastoma-associated protein. (928 aa) | ||||
CREBBP | CREB-binding protein. (2360 aa) | ||||
CCNE1 | LOW QUALITY PROTEIN: G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) | ||||
YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (178 aa) | ||||
ENSEEUP00000005302 | annotation not available (113 aa) | ||||
ENSEEUP00000005308 | annotation not available (706 aa) | ||||
ENSEEUP00000005358 | annotation not available (228 aa) | ||||
ENSEEUP00000005380 | annotation not available (91 aa) | ||||
MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (216 aa) |