(56 nodes) Nucleotide excision repair network (Echinops telfairi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DDB2	Damage specific DNA binding protein 2. (428 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	LIG1	DNA ligase 1. (911 aa)
	GTF2H3	General transcription factor IIH subunit 3. (201 aa)
	ENSETEP00000000824	annotation not available (1190 aa)
	ENSETEP00000000855	annotation not available (1139 aa)
	ENSETEP00000003218	annotation not available (389 aa)
	RFC1	Replication factor C subunit 1. (1134 aa)
	CETN1	Centrin 1. (172 aa)
	ERCC2	ERCC excision repair 2, TFIIH core complex helicase subunit. (729 aa)
	ENSETEP00000004005	annotation not available (503 aa)
	SASS6	SAS-6 centriolar assembly protein. (650 aa)
	ENSETEP00000005239	annotation not available (111 aa)
	GTF2H1	General transcription factor IIH subunit 1. (548 aa)
	CUL4B	Cullin 4B. (852 aa)
	ERCC3	ERCC excision repair 3, TFIIH core complex helicase subunit. (784 aa)
	FBH1	F-box DNA helicase 1. (1049 aa)
	CDK7	Cyclin dependent kinase 7. (346 aa)
	RFC4	Replication factor C subunit 4. (362 aa)
	RFC5	Replication factor C subunit 5. (339 aa)
	ATAD5	ATPase family AAA domain containing 5. (1829 aa)
	RPA1	Replication protein A1. (611 aa)
	ZNF609	Zinc finger protein 609. (1222 aa)
	POLE	DNA polymerase epsilon, catalytic subunit. (2060 aa)
	XPC	XPC complex subunit, DNA damage recognition and repair factor. (921 aa)
	ENSETEP00000013004	annotation not available (266 aa)
	RPA2	Replication protein A2. (231 aa)
	ERCC8	ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (918 aa)
	ENSETEP00000012362	annotation not available (121 aa)
	CLSPN	Claspin. (1330 aa)
	ENSETEP00000012326	annotation not available (468 aa)
	ERCC6	ERCC excision repair 6, chromatin remodeling factor. (1285 aa)
	PPIL3	Peptidylprolyl isomerase like 3. (103 aa)
	DDX11	DEAD/H-box helicase 11. (919 aa)
	STN1	STN1 subunit of CST complex. (368 aa)
	GTF2H5	General transcription factor IIH subunit 5. (59 aa)
	ENSETEP00000010798	annotation not available (433 aa)
	ENSETEP00000010770	annotation not available (82 aa)
	CUL4A	Cullin 4A. (711 aa)
	ZNF608	Zinc finger protein 608. (1504 aa)
	ENSETEP00000010514	annotation not available (244 aa)
	CDK20	Cyclin dependent kinase 20. (419 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (406 aa)
	ENSETEP00000008738	annotation not available (309 aa)
	XPA	XPA, DNA damage recognition and repair factor. (270 aa)
	YJU2	YJU2 splicing factor homolog. (197 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (116 aa)
	ENSETEP00000007307	annotation not available (106 aa)
	WDR76	WD repeat domain 76. (621 aa)
	POLE3	DNA polymerase epsilon 3, accessory subunit. (136 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (470 aa)
	ENSETEP00000005344	annotation not available (260 aa)
	ENSETEP00000005314	annotation not available (171 aa)
	ENSETEP00000000809	annotation not available (795 aa)
	ENSETEP00000000719	annotation not available (464 aa)

Your Current Organism:

Echinops telfairi

NCBI taxonomy Id: 9371
Other names: E. telfairi, Echinops telfairii, lesser hedgehog tenrec, small Madagascar hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CLSPN	ENSETEP00000014545	ENSETEP00000012330	ATPase family AAA domain containing 5.	Claspin.	0.872
ATAD5	CUL4A	ENSETEP00000014545	ENSETEP00000010595	ATPase family AAA domain containing 5.	Cullin 4A.	0.613
ATAD5	CUL4B	ENSETEP00000014545	ENSETEP00000016579	ATPase family AAA domain containing 5.	Cullin 4B.	0.613
ATAD5	DDB2	ENSETEP00000014545	ENSETEP00000000323	ATPase family AAA domain containing 5.	Damage specific DNA binding protein 2.	0.503
ATAD5	DDX11	ENSETEP00000014545	ENSETEP00000011536	ATPase family AAA domain containing 5.	DEAD/H-box helicase 11.	0.862
ATAD5	ENSETEP00000000809	ENSETEP00000014545	ENSETEP00000000809	ATPase family AAA domain containing 5.	annotation not available	0.861
ATAD5	ENSETEP00000000824	ENSETEP00000014545	ENSETEP00000000824	ATPase family AAA domain containing 5.	annotation not available	0.802
ATAD5	ENSETEP00000000855	ENSETEP00000014545	ENSETEP00000000855	ATPase family AAA domain containing 5.	annotation not available	0.641
ATAD5	ENSETEP00000004005	ENSETEP00000014545	ENSETEP00000004005	ATPase family AAA domain containing 5.	annotation not available	0.802
ATAD5	ENSETEP00000005239	ENSETEP00000014545	ENSETEP00000005239	ATPase family AAA domain containing 5.	annotation not available	0.680
ATAD5	ENSETEP00000005344	ENSETEP00000014545	ENSETEP00000005344	ATPase family AAA domain containing 5.	annotation not available	0.974
ATAD5	ENSETEP00000010514	ENSETEP00000014545	ENSETEP00000010514	ATPase family AAA domain containing 5.	annotation not available	0.974
ATAD5	ENSETEP00000010798	ENSETEP00000014545	ENSETEP00000010798	ATPase family AAA domain containing 5.	annotation not available	0.793
ATAD5	ENSETEP00000012326	ENSETEP00000014545	ENSETEP00000012326	ATPase family AAA domain containing 5.	annotation not available	0.793
ATAD5	ENSETEP00000012362	ENSETEP00000014545	ENSETEP00000012362	ATPase family AAA domain containing 5.	annotation not available	0.680
ATAD5	ENSETEP00000013004	ENSETEP00000014545	ENSETEP00000013004	ATPase family AAA domain containing 5.	annotation not available	0.868
ATAD5	ERCC2	ENSETEP00000014545	ENSETEP00000003705	ATPase family AAA domain containing 5.	ERCC excision repair 2, TFIIH core complex helicase subunit.	0.731
ATAD5	ERCC4	ENSETEP00000014545	ENSETEP00000012402	ATPase family AAA domain containing 5.	ERCC excision repair 4, endonuclease catalytic subunit.	0.800
ATAD5	FBH1	ENSETEP00000014545	ENSETEP00000016132	ATPase family AAA domain containing 5.	F-box DNA helicase 1.	0.757
ATAD5	GTF2H1	ENSETEP00000014545	ENSETEP00000005182	ATPase family AAA domain containing 5.	General transcription factor IIH subunit 1.	0.617