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| | EHQ36019.1 | Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: mba:Mbar_A0070 phosphoesterase; PFAM: Metallophosphoesterase; SPTR: Phosphoesterase. (434 aa) |
| | EHQ37088.1 | PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; COGs: COG0817 Holliday junction resolvasome endonuclease subunit; HAMAP: Crossover junction endodeoxyribonuclease RuvC; InterPro IPR002176; KEGG: mbn:Mboo_0111 Holliday junction resolvase; PFAM: Crossover junction endodeoxyribonuclease RuvC; SPTR: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: Crossover junction endodeoxyribonuclease RuvC. (156 aa) |
| | EHQ37087.1 | PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit; COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; HAMAP: Holliday junction ATP-dependent DNA helicase ruvA; InterPro IPR013849:IPR011114:IPR000085:IPR003583; KEGG: mbn:Mboo_0112 Holliday junction DNA helicase RuvA; PFAM: DNA helicase, Holliday junction RuvA type, domain I, bacterial; DNA helicase, Holliday junction RuvA type, domain III, C-terminal; SPTR: Holliday junction DNA helicase RuvA; TIGRFAM: Bacterial DNA recombination protein RuvA. (199 aa) |
| | ruvB | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (332 aa) |
| | EHQ37036.1 | PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904:IPR003265; KEGG: mpi:Mpet_2588 DNA-(apurinic or apyrimidinic site) lyase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; SMART: HhH-GPD domain; SPTR: DNA-(Apurinic or apyrimidinic site) lyase. (321 aa) |
| | EHQ37035.1 | Hypothetical protein; PFAM: Pathogenicity locus; KEGG: mpi:Mpet_2586 hypothetical protein; SPTR: Putative uncharacterized protein. (93 aa) |
| | EHQ37015.1 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (545 aa) |
| | nfo | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (281 aa) |
| | EHQ36987.1 | Restriction endonuclease, type II, MjaII; PFAM: MjaII restriction endonuclease; InterPro IPR019045; KEGG: cyh:Cyan8802_4357 hypothetical protein; PFAM: Restriction endonuclease, type II, MjaII; SPTR: Putative uncharacterized protein. (289 aa) |
| | EHQ36986.1 | DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase; InterPro IPR002941; KEGG: pth:PTH_1123 hypothetical protein; PFAM: DNA methylase N-4/N-6; SPTR: Putative uncharacterized protein. (408 aa) |
| | EHQ36901.1 | Protein of unknown function DUF650; Involved in DNA damage repair; Belongs to the Nre family. (386 aa) |
| | lig | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (549 aa) |
| | EHQ36890.1 | PFAM: Beta propeller domain; COGs: COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats; InterPro IPR019198; KEGG: mhu:Mhun_1971 hypothetical protein; PFAM: Beta propeller domain; SPTR: Putative uncharacterized protein. (675 aa) |
| | EHQ36869.1 | Transposase IS4 family protein; PFAM: Transposase DDE domain; InterPro IPR002559; KEGG: mhu:Mhun_2821 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family. (432 aa) |
| | top6A | Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (362 aa) |
| | top6B | DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (600 aa) |
| | rfcL | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (497 aa) |
| | EHQ36629.1 | PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; COGs: COG1202 Superfamily II helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: mpi:Mpet_2114 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein. (667 aa) |
| | EHQ36584.1 | PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: cpc:Cpar_0961 restriction modification system DNA specificity domain; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Restriction modification system DNA specificity domain. (583 aa) |
| | EHQ36581.1 | InterPro IPR000055; KEGG: hmo:HM1_0633 type I restriction modification DNA specificity domain; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Type i restriction modification DNA specificity domain. (183 aa) |
| | EHQ36568.1 | PFAM: PHP domain; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR003141; KEGG: mbn:Mboo_2310 hypothetical protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP C-terminal domain protein. (213 aa) |
| | EHQ36512.1 | Transposase, IS605 OrfB family; PFAM: Helix-turn-helix domain; Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR001959:IPR010095; KEGG: mmh:Mmah_0063 transposase, IS605 OrfB family; PFAM: Transposase, probable, IS891/IS1136/IS1341; Transposase, IS605 OrfB, C-terminal; SPTR: Transposase, IS605 OrfB family; TIGRFAM: Transposase, IS605 OrfB, C-terminal. (370 aa) |
| | EHQ36505.1 | DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR011545:IPR001650:IPR018973:IPR014001; KEGG: gym:GYMC10_1045 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Protein of unknown function DUF1998; SMART: DEAD-like helicase, N-terminal; SPTR: DEAD/DEAH box helicase domain protein. (1763 aa) |
| | EHQ36457.1 | PFAM: Phage integrase family; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: mpi:Mpet_2327 integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Integrase family protein. (407 aa) |
| | EHQ36431.1 | Resolvase domain-containing protein; PFAM: Resolvase, N terminal domain; Helix-turn-helix domain of resolvase; COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119:IPR006120; KEGG: shw:Sputw3181_4073 resolvase domain-containing protein; PFAM: Resolvase, N-terminal; Resolvase, helix-turn-helix region; SPTR: Probable DNA-invertase (Site-specific recombinase). (193 aa) |
| | EHQ36413.1 | PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Domain of unknown function (DUF3559); Type III restriction enzyme, res subunit; COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR006935:IPR014001; KEGG: tye:THEYE_A1697 type I site-specific deoxyribonuclease; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SMART: DEAD-like helicase, N-terminal; SPTR: Type I site-specific deoxyribo [...] (947 aa) |
| | EHQ36411.1 | PFAM: Type I restriction modification DNA specificity domain; InterPro IPR000055; KEGG: rhi:NGR_c01350 putative restriction endonuclease type I, S subunit; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Putative restriction endonuclease type I, S subunit. (542 aa) |
| | EHQ36406.1 | PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: tye:THEYE_A1689 type I restriction enzyme EcoKI M protein; PFAM: DNA methylase, adenine-specific; SPTR: Type I restriction enzyme EcoKI M protein. (485 aa) |
| | EHQ36372.1 | Transposase, IS4 family; PFAM: Transposase DDE domain; InterPro IPR002559; KEGG: mhu:Mhun_2821 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family; manually curated. (448 aa) |
| | EHQ36300.1 | ATPase-like protein; COGs: COG1106 ATPase; KEGG: sul:SYO3AOP1_0488 ATPase-like protein; SPTR: Putative uncharacterized protein. (363 aa) |
| | EHQ36277.1 | PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: mpi:Mpet_1674 site-specific DNA-methyltransferase (adenine-specific); PFAM: DNA methylase, adenine-specific; SPTR: Site-specific DNA-methyltransferase (Adenine-specific). (500 aa) |
| | EHQ36273.1 | PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: tjr:TherJR_0900 restriction modification system DNA specificity domain protein; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Putative specificity protein s. (410 aa) |
| | EHQ36270.1 | PFAM: Domain of unknown function (DUF3387); Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR006935:IPR014001:IPR004473; KEGG: mpi:Mpet_1680 type I site-specific deoxyribonuclease; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART [...] (1022 aa) |
| | EHQ36234.1 | Hypothetical protein; PFAM: N-6 DNA Methylase; KEGG: mhu:Mhun_1081 hypothetical protein; SPTR: Putative uncharacterized protein. (1112 aa) |
| | EHQ36198.1 | Transposase IS4 family protein; PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: mbu:Mbur_2442 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase. (311 aa) |
| | EHQ36164.1 | DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR011545:IPR001650:IPR018973:IPR014001; KEGG: mst:Msp_0367 helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Protein of unknown function DUF1998; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Predicted helicase. (855 aa) |
| | EHQ36156.1 | SMC domain protein; PFAM: RecF/RecN/SMC N terminal domain; COGs: COG4637 ATPase; InterPro IPR003395; KEGG: sli:Slin_5825 SMC domain protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: SMC domain protein. (381 aa) |
| | EHQ36108.1 | Transposase IS200-family protein; PFAM: Transposase IS200 like; COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: adg:Adeg_1688 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase IS200-family protein; manually curated. (134 aa) |
| | EHQ36107.1 | Transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095; KEGG: tac:Ta0475 transposase related protein; PFAM: Transposase, IS605 OrfB, C-terminal; SPTR: Transposase related protein; TIGRFAM: Transposase, IS605 OrfB, C-terminal. (347 aa) |
| | EHQ36094.1 | Transposase IS200-family protein; PFAM: Transposase IS200 like; COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: adg:Adeg_1688 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase IS200-family protein; manually curated. (134 aa) |
| | EHQ36093.1 | Transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095; KEGG: tac:Ta0475 transposase related protein; PFAM: Transposase, IS605 OrfB, C-terminal; SPTR: Transposase related protein; TIGRFAM: Transposase, IS605 OrfB, C-terminal. (347 aa) |
| | EHQ36078.1 | SMC domain-containing protein; COGs: COG4637 ATPase; KEGG: chl:Chy400_2026 SMC domain-containing protein; SPTR: SMC domain protein. (362 aa) |
| | EHQ36068.1 | PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; COGs: COG1201 Lhr-like helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: csc:Csac_1679 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein. (527 aa) |
| | EHQ36044.1 | SMC domain protein; PFAM: RecF/RecN/SMC N terminal domain; COGs: COG3950 ATP-binding protein involved in virulence; InterPro IPR003395:IPR003593; KEGG: mar:MAE_39710 ATPase; PFAM: RecF/RecN/SMC protein, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATPase. (436 aa) |
| | EHQ36012.1 | Uncharacterized protein family UPF0310; PFAM: Protein of unknown function DUF55; COGs: COG1673 conserved hypothetical protein; InterPro IPR002740; KEGG: mpi:Mpet_0775 hypothetical protein; PFAM: Uncharacterised protein family UPF0310; SPTR: Putative uncharacterized protein. (182 aa) |
| | EHQ36004.1 | Uncharacterized protein family UPF0310; PFAM: Protein of unknown function DUF55; COGs: COG1673 conserved hypothetical protein; InterPro IPR002740; KEGG: mpi:Mpet_0775 hypothetical protein; PFAM: Uncharacterised protein family UPF0310; SPTR: Putative uncharacterized protein. (170 aa) |
| | EHQ35959.1 | DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; COGs: COG2231 Uncharacterized protein related to Endonuclease III; InterPro IPR003265; KEGG: mpi:Mpet_1694 HhH-GPD family protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein. (214 aa) |
| | EHQ35946.1 | PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: mpi:Mpet_1667 xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain protein TIM barrel. (258 aa) |
| | EHQ35883.1 | UvrD/REP helicase; PFAM: Domain of unknown function DUF83; Nuclease-related domain; UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR011528:IPR000212; KEGG: mma:MM_0190 DNA helicase II; PFAM: DNA helicase, UvrD/REP type; NERD; SPTR: DNA helicase II. (1332 aa) |
| | priS | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (380 aa) |
| | EHQ35784.1 | PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit; COGs: COG1570 Exonuclease VII large subunit; HAMAP: Exodeoxyribonuclease 7 large subunit; InterPro IPR003753:IPR004365:IPR020579; KEGG: mpi:Mpet_1838 exodeoxyribonuclease VII large subunit; PFAM: Exonuclease VII, large subunit, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Exodeoxyribonuclease VII, large subunit; TIGRFAM: Exonuclease VII, large subunit. (441 aa) |
| | EHQ35782.1 | PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR001719:IPR012307; KEGG: mpi:Mpet_1840 xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SMART: Endodeoxyribonuclease IV; SPTR: Xylose isomerase domain protein TIM barrel. (273 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (705 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (944 aa) |
| | xerA | Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerA subfamily. (303 aa) |
| | EHQ35752.1 | PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg); COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904; KEGG: mpi:Mpet_0357 8-oxoguanine DNA glycosylase domain-containing protein; PFAM: 8-oxoguanine DNA glycosylase, N-terminal; SPTR: 8-oxoguanine DNA glycosylase domain protein. (292 aa) |
| | radB | DNA repair and recombination protein radB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (225 aa) |
| | EHQ35683.1 | methylated-DNA/protein- cysteinemethyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: mpi:Mpet_1922 methylated-DNA/protein-cysteinemethyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR:Methylated-DNA/protein-cysteinemethyltransfera se; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding. (163 aa) |
| | EHQ35676.1 | PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006172:IPR006133:IPR006134; KEGG: mpi:Mpet_1929 DNA polymerase B region; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase. (843 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (935 aa) |
| | EHQ35645.1 | Type IIS restriction enzyme; PFAM: Eco57I restriction endonuclease; KEGG: mma:MM_0156 type IIS restriction enzyme; SPTR: Type IIS restriction enzyme. (611 aa) |
| | EHQ35641.1 | KEGG: mma:MM_0156 type IIS restriction enzyme; SPTR: Type IIS restriction enzyme. (588 aa) |
| | EHQ35636.1 | PFAM: Phage integrase family; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: mbn:Mboo_0506 phage integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Phage integrase family protein. (490 aa) |
| | EHQ35579.1 | ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001:IPR001650:IPR018329:IPR011545:IPR 018982:IPR002121; KEGG: rci:RCIX1772 ATP-dependent DNA helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; RQC domain; Helicase/RNase D C-terminal, HRDC domain; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: [...] (1165 aa) |
| | EHQ35473.1 | SMC domain protein; TIGRFAM: exonuclease SbcC; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: gur:Gura_1980 SMC domain-containing protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: SMC domain protein. (1222 aa) |
| | EHQ35472.1 | Exodeoxyribonuclease I subunit D; PFAM: Calcineurin-like phosphoesterase; Type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD; COGs: COG0420 DNA repair exonuclease; InterPro IPR004593:IPR004843; KEGG: gur:Gura_1979 nuclease SbcCD, D subunit; PFAM: Metallophosphoesterase; SPTR: Exodeoxyribonuclease I subunit D; TIGRFAM: Exonuclease SbcD. (409 aa) |
| | polB | DNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (497 aa) |
| | EHQ35415.1 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (439 aa) |
| | hel308 | Ski2-type helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (787 aa) |
| | EHQ35383.1 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (379 aa) |
| | EHQ35369.1 | PFAM: Phage integrase family; InterPro IPR002104; KEGG: mac:MA2599 phage integrase; PFAM: Integrase, catalytic core, phage; SPTR: Phage integrase. (190 aa) |
| | EHQ35342.1 | PFAM: Phage integrase family; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: mpi:Mpet_2327 integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Integrase family protein. (397 aa) |
| | EHQ35303.1 | ATPase; COGs: COG4637 ATPase; KEGG: mpi:Mpet_1157 ATPase; SPTR: ATPase. (415 aa) |
| | EHQ35289.1 | PFAM: OB-fold nucleic acid binding domain; COGs: COG1599 Single-stranded DNA-binding replication protein A (RPA) large (70 kD) subunit and related ssDNA-binding protein; InterPro IPR004365; KEGG: mpi:Mpet_0146 nucleic acid binding OB-fold tRNA/helicase-type protein; PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Nucleic acid binding OB-fold tRNA/helicase-type. (424 aa) |
| | EHQ35287.1 | PFAM: OB-fold nucleic acid binding domain; COGs: COG1599 Single-stranded DNA-binding replication protein A (RPA) large (70 kD) subunit and related ssDNA-binding protein; InterPro IPR004365; KEGG: mpi:Mpet_0146 nucleic acid binding OB-fold tRNA/helicase-type protein; PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Nucleic acid binding OB-fold tRNA/helicase-type. (417 aa) |
| | EHQ35284.1 | COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; KEGG: mpi:Mpet_0149 oxygen-sensitive ribonucleoside-triphosphate reductase-like protein; SPTR: Oxygen-sensitive ribonucleoside-triphosphate reductase-like protein. (120 aa) |
| | EHQ35231.1 | KEGG: vdi:Vdis_0515 hypothetical protein; SPTR: Putative uncharacterized protein. (449 aa) |
| | EHQ35230.1 | PFAM: D12 class N6 adenine-specific DNA methyltransferase; TIGRFAM: DNA adenine methylase (dam); COGs: COG0338 Site-specific DNA methylase; InterPro IPR012327:IPR012326; KEGG: mev:Metev_0669 DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: DNA adenine methylase; TIGRFAM: DNA adenine methylase. (357 aa) |
| | EHQ35206.1 | Transposase, IS4 family; PFAM: Transposase DDE domain; COGs: COG5421 Transposase; InterPro IPR002559; KEGG: mhu:Mhun_1523 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family. (536 aa) |
| | EHQ35193.1 | SMC domain protein; COGs: COG4637 ATPase; InterPro IPR003395; KEGG: dma:DMR_16070 hypothetical protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: Putative uncharacterized protein. (400 aa) |
| | EHQ35128.1 | PFAM: DNA methylase; InterPro IPR002941; KEGG: DNA methylase N-4/N-6 domain-containing protein; PFAM: DNA methylase N-4/N-6; SPTR: Methyltransferase DNA modification enzyme. (433 aa) |
| | EHQ35110.1 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: mem:Memar_1591 HAD family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1. (218 aa) |
| | EHQ35100.1 | ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001:IPR001650:IPR002121:IPR011545:IPR 018982:IPR006293:IPR018329; KEGG: mac:MA4507 DNA helicase RecQ; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; RQC domain; Helicase/RNase D C-terminal, HRDC domain; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase [...] (720 aa) |
| | cas1 | CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (311 aa) |
| | polC | DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1299 aa) |
| | EHQ35007.1 | Heat shock protein DnaJ domain protein; PFAM: DnaJ domain; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: mpi:Mpet_0567 heat shock protein DnaJ domain-containing protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein. (211 aa) |
| | EHQ35004.1 | PFAM: PHP domain; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: mpi:Mpet_0564 PHP domain-containing protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein. (234 aa) |
| | EHQ34980.1 | Deoxyribodipyrimidine photo-lyase type I; PFAM: FAD binding domain of DNA photolyase; DNA photolyase; COGs: COG0415 Deoxyribodipyrimidine photolyase; InterPro IPR006050:IPR005101; KEGG: mpi:Mpet_2798 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase, FAD-binding/Cryptochrome, C-terminal; DNA photolyase, N-terminal; SPTR: Deoxyribodipyrimidine photo-lyase. (476 aa) |
| | dbh | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (364 aa) |
| | dnaJ | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (379 aa) |
| | EHQ34867.1 | Hypothetical protein; KEGG: mpi:Mpet_0705 nucleic acid binding OB-fold tRNA/helicase-type protein; SPTR: Nucleic acid binding, OB-fold, tRNA/helicase-type. (560 aa) |
| | radA | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (324 aa) |
| | fen | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (333 aa) |
| | smc | Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1146 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (639 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (856 aa) |
| | EHQ34785.1 | Helicase domain-containing protein; PFAM: Helicase conserved C-terminal domain; Helix-hairpin-helix motif; DEAD/DEAH box helicase; COGs: COG1111 ERCC4-like helicase; InterProIPR011545:IPR001650:IPR006166:IPR000445:IPR 014001:IPR003583; KEGG: mpi:Mpet_0792 helicase domain-containing protein; PFAM: DNA/RNA helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ERCC4 domain; Helix-hairpin-helix motif; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helix-hairpin-helix DNA-binding motif, class 1; SPTR: Helicase domain protein. (776 aa) |
| | EHQ34770.1 | Hypothetical protein; PFAM: Archaeal ATPase; InterPro IPR011579; KEGG: ATPase; SPTR: Putative uncharacterized protein. (398 aa) |
| | EHQ34769.1 | PFAM: PHP domain; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: mhu:Mhun_1232 PHP-like; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP-like protein. (287 aa) |
| | EHQ34733.1 | PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit; COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR014001:IPR007409:IPR006935; KEGG: cby:CLM_2294 type III restriction protein res subunit; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal; SPTR: Type III restriction protein res subunit. (1010 aa) |
| | EHQ34731.1 | PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; KEGG: sgy:Sgly_0846 restriction modification system DNA specificity domain protein; SPTR: Restriction modification system DNA specificity domain protein. (446 aa) |
| | EHQ34729.1 | PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: cby:CLM_2296 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific; SPTR: N-6 DNA methylase. (573 aa) |
| | EHQ34725.1 | Transposase IS200-family protein; PFAM: Transposase IS200 like; COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: adg:Adeg_1688 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase IS200-family protein; manually curated. (140 aa) |
| | EHQ34724.1 | Transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095; KEGG: tac:Ta0475 transposase related protein; PFAM: Transposase, IS605 OrfB, C-terminal; SPTR: Transposase related protein; TIGRFAM: Transposase, IS605 OrfB, C-terminal. (346 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (217 aa) |
| | EHQ34700.1 | SMC domain protein; COGs: COG4637 ATPase; InterPro IPR003395; KEGG: dhd:Dhaf_0103 SMC domain protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: SMC domain protein. (403 aa) |
| | EHQ34656.1 | Transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095; KEGG: tac:Ta0475 transposase related protein; PFAM: Transposase, IS605 OrfB, C-terminal; SPTR: Transposase related protein; TIGRFAM: Transposase, IS605 OrfB, C-terminal. (347 aa) |
| | EHQ34655.1 | Transposase IS200-family protein; PFAM: Transposase IS200 like; COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: adg:Adeg_1688 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase IS200-family protein; manually curated. (134 aa) |
| | EHQ34590.1 | Transposase IS4 family protein; PFAM: Transposase DDE domain; InterPro IPR002559; KEGG: mhu:Mhun_1908 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family. (448 aa) |
| | EHQ34581.1 | Replication factor C; PFAM: ATPase family associated with various cellular activities (AAA); Replication factor C; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003959:IPR013748; KEGG: mpi:Mpet_0988 replication factor C; PFAM: Replication factor C; ATPase, AAA-type, core; SPTR: Replication factor C. (332 aa) |
| | rfcS | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (325 aa) |
| | EHQ34568.1 | ATP dependent helicase, Lhr family; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase; COGs: COG1201 Lhr-like helicase; InterPro IPR014001:IPR001650:IPR011545:IPR013701; KEGG: mpi:Mpet_0975 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; DEAD/H associated; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein. (897 aa) |
| | EHQ34563.1 | PFAM: Phage integrase family; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: mbn:Mboo_0506 phage integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Phage integrase family protein. (411 aa) |
| | EHQ34554.1 | PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; COGs: COG1204 Superfamily II helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: mfa:Mfla_1218 DEAD/DEAH box helicase-like protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase-like protein. (1053 aa) |
| | EHQ34552.1 | DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR014001:IPR001650:IPR011545:IPR018973; KEGG: ttm:Tthe_0932 protein of unknown function DUF1998; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Protein of unknown function DUF1998; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: Putative uncharacterized protein. (1782 aa) |
| | EHQ34550.1 | KEGG: dau:Daud_0394 hypothetical protein; SPTR: Putative uncharacterized protein. (1691 aa) |
| | EHQ34544.1 | PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR014001:IPR001650:IPR011545; KEGG: aoe:Clos_1857 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein. (1970 aa) |
| | EHQ34527.1 | Hypothetical protein; PFAM: Archaeal ATPase; KEGG: mhu:Mhun_2057 hypothetical protein; SPTR: Putative uncharacterized protein. (528 aa) |
| | EHQ34466.1 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); COGs: COG0708 Exonuclease III; InterPro IPR004808:IPR000097:IPR005135; KEGG: mpi:Mpet_1338 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Exodeoxyribonuclease III; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth; manually curated. (256 aa) |
| | EHQ34302.1 | Transposase IS4 family protein; PFAM: Transposase DDE domain; Transposase domain (DUF772); COGs: COG3039 Transposase and inactivated derivatives IS5 family; InterPro IPR002559; KEGG: mbu:Mbur_2442 transposase, IS4; PFAM: Transposase, IS4-like; SPTR: Transposase. (311 aa) |
| | dnaG | UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (403 aa) |
| | priL | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (381 aa) |
| | pcn | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (247 aa) |
| | EHQ34222.1 | Ribonucleoside-triphosphate reductase class III catalytic subunit; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; intein N-terminal splicing region; COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR003587:IPR012833:IPR006141; KEGG: mpi:Mpet_1249 anaerobic ribonucleoside-triphosphate reductase; SMART: Hedgehog/intein hint, N-terminal; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; Intein splicing site. (1212 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (649 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (523 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (977 aa) |
| | EHQ34202.1 | PFAM: Uracil DNA glycosylase superfamily; COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; KEGG: mpi:Mpet_1152 hypothetical protein; SPTR: Putative uncharacterized protein. (180 aa) |
