6 items (Pteropus alecto) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L5JNT3_PTEAL	Autophagy protein 5; Involved in autophagic vesicle formation. (216 aa)
	ATG16L2	Autophagy-related protein 16-2. (622 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (743 aa)
	WIPI1	WD repeat domain phosphoinositide-interacting protein 1. (437 aa)
	ATG16L1	Autophagy-related protein 16-1. (608 aa)
	L5L405_PTEAL	Autophagy-related protein 3. (336 aa)

Your Current Organism:

Pteropus alecto

NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG16L1	ATG16L2	L5L1F1	L5K4X7	Autophagy-related protein 16-1.	Autophagy-related protein 16-2.	0.911
ATG16L1	ATG7	L5L1F1	L5KAW1	Autophagy-related protein 16-1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.878
ATG16L1	L5JNT3_PTEAL	L5L1F1	L5JNT3	Autophagy-related protein 16-1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	L5L405_PTEAL	L5L1F1	L5L405	Autophagy-related protein 16-1.	Autophagy-related protein 3.	0.974
ATG16L1	WIPI1	L5L1F1	L5KNI1	Autophagy-related protein 16-1.	WD repeat domain phosphoinositide-interacting protein 1.	0.993
ATG16L2	ATG16L1	L5K4X7	L5L1F1	Autophagy-related protein 16-2.	Autophagy-related protein 16-1.	0.911
ATG16L2	ATG7	L5K4X7	L5KAW1	Autophagy-related protein 16-2.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.715
ATG16L2	L5JNT3_PTEAL	L5K4X7	L5JNT3	Autophagy-related protein 16-2.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.945
ATG16L2	L5L405_PTEAL	L5K4X7	L5L405	Autophagy-related protein 16-2.	Autophagy-related protein 3.	0.911
ATG16L2	WIPI1	L5K4X7	L5KNI1	Autophagy-related protein 16-2.	WD repeat domain phosphoinositide-interacting protein 1.	0.992
ATG7	ATG16L1	L5KAW1	L5L1F1	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy-related protein 16-1.	0.878
ATG7	ATG16L2	L5KAW1	L5K4X7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy-related protein 16-2.	0.715
ATG7	L5JNT3_PTEAL	L5KAW1	L5JNT3	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy protein 5; Involved in autophagic vesicle formation.	0.952
ATG7	L5L405_PTEAL	L5KAW1	L5L405	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy-related protein 3.	0.999
ATG7	WIPI1	L5KAW1	L5KNI1	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	WD repeat domain phosphoinositide-interacting protein 1.	0.839
L5JNT3_PTEAL	ATG16L1	L5JNT3	L5L1F1	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 16-1.	0.999
L5JNT3_PTEAL	ATG16L2	L5JNT3	L5K4X7	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 16-2.	0.945
L5JNT3_PTEAL	ATG7	L5JNT3	L5KAW1	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.952
L5JNT3_PTEAL	L5L405_PTEAL	L5JNT3	L5L405	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 3.	0.989
L5JNT3_PTEAL	WIPI1	L5JNT3	L5KNI1	Autophagy protein 5; Involved in autophagic vesicle formation.	WD repeat domain phosphoinositide-interacting protein 1.	0.925