(16 nodes) VEGF ligand-receptor interactions, and Neutrophil extravasation network (Pteropus alecto)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (190 aa)
	PGF	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family. (162 aa)
	L5JR35_PTEAL	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (179 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	L5JUP9_PTEAL	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (640 aa)
	KDR	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1344 aa)
	FLT4	Vascular endothelial growth factor receptor 3. (771 aa)
	FGF20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	L5KBT4_PTEAL	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (172 aa)
	VEGFC	Vascular endothelial growth factor C. (277 aa)
	PECAM1	Platelet endothelial cell adhesion molecule. (742 aa)
	VEGFD	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (350 aa)
	VEGFB	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (81 aa)
	CDH5	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
	L5L458_PTEAL	Vascular endothelial growth factor receptor kdr-like protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1013 aa)
	L5L639_PTEAL	Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1247 aa)

Your Current Organism:

Pteropus alecto

NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH5	FGF20	L5KU39	L5KBF5	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.440
CDH5	FGF6	L5KU39	L5JU70	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.427
CDH5	FLT4	L5KU39	L5JY59	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Vascular endothelial growth factor receptor 3.	0.619
CDH5	KDR	L5KU39	L5JWG9	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.929
CDH5	L5JUP9_PTEAL	L5KU39	L5JUP9	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.619
CDH5	L5L458_PTEAL	L5KU39	L5L458	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Vascular endothelial growth factor receptor kdr-like protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.406
CDH5	L5L639_PTEAL	L5KU39	L5L639	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.610
CDH5	PECAM1	L5KU39	L5KNK7	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Platelet endothelial cell adhesion molecule.	0.999
CDH5	VEGFA	L5KU39	L5JNB5	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family.	0.434
FGF20	CDH5	L5KBF5	L5KU39	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	0.440
FGF20	FGF6	L5KBF5	L5JU70	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.400
FGF20	FLT4	L5KBF5	L5JY59	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 3.	0.752
FGF20	KDR	L5KBF5	L5JWG9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.797
FGF20	PECAM1	L5KBF5	L5KNK7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet endothelial cell adhesion molecule.	0.546
FGF20	PGF	L5KBF5	L5JQM1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.504
FGF20	VEGFA	L5KBF5	L5JNB5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family.	0.516
FGF6	CDH5	L5JU70	L5KU39	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	0.427
FGF6	FGF20	L5JU70	L5KBF5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.400
FGF6	FLT4	L5JU70	L5JY59	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 3.	0.778
FGF6	KDR	L5JU70	L5JWG9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.800