(10 nodes) VEGF ligand-receptor interactions network (Pteropus alecto)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PGF	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family. (162 aa)
	L5JR35_PTEAL	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (179 aa)
	L5JUP9_PTEAL	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (640 aa)
	FLT4	Vascular endothelial growth factor receptor 3. (771 aa)
	L5KBT4_PTEAL	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (172 aa)
	VEGFC	Vascular endothelial growth factor C. (277 aa)
	VEGFD	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (350 aa)
	VEGFB	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (81 aa)
	L5L458_PTEAL	Vascular endothelial growth factor receptor kdr-like protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1013 aa)
	L5L639_PTEAL	Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1247 aa)

Your Current Organism:

Pteropus alecto

NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FLT4	L5JR35_PTEAL	L5JY59	L5JR35	Vascular endothelial growth factor receptor 3.	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	0.866
FLT4	L5JUP9_PTEAL	L5JY59	L5JUP9	Vascular endothelial growth factor receptor 3.	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.623
FLT4	L5KBT4_PTEAL	L5JY59	L5KBT4	Vascular endothelial growth factor receptor 3.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.888
FLT4	PGF	L5JY59	L5JQM1	Vascular endothelial growth factor receptor 3.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.846
FLT4	VEGFB	L5JY59	L5KRL2	Vascular endothelial growth factor receptor 3.	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	0.866
FLT4	VEGFC	L5JY59	L5KDE8	Vascular endothelial growth factor receptor 3.	Vascular endothelial growth factor C.	0.959
FLT4	VEGFD	L5JY59	L5KNN4	Vascular endothelial growth factor receptor 3.	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	0.885
L5JR35_PTEAL	FLT4	L5JR35	L5JY59	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor receptor 3.	0.866
L5JR35_PTEAL	L5JUP9_PTEAL	L5JR35	L5JUP9	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.635
L5JR35_PTEAL	L5L458_PTEAL	L5JR35	L5L458	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor receptor kdr-like protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.741
L5JR35_PTEAL	L5L639_PTEAL	L5JR35	L5L639	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.885
L5JR35_PTEAL	PGF	L5JR35	L5JQM1	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.586
L5JUP9_PTEAL	FLT4	L5JUP9	L5JY59	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor receptor 3.	0.623
L5JUP9_PTEAL	L5JR35_PTEAL	L5JUP9	L5JR35	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	0.635
L5JUP9_PTEAL	L5KBT4_PTEAL	L5JUP9	L5KBT4	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.888
L5JUP9_PTEAL	PGF	L5JUP9	L5JQM1	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.579
L5JUP9_PTEAL	VEGFB	L5JUP9	L5KRL2	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.	0.635
L5JUP9_PTEAL	VEGFC	L5JUP9	L5KDE8	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor C.	0.888
L5JUP9_PTEAL	VEGFD	L5JUP9	L5KNN4	Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	0.686
L5KBT4_PTEAL	FLT4	L5KBT4	L5JY59	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor receptor 3.	0.888