STRINGSTRING
ATG14 ATG14 FIS1 FIS1 FUNDC1 FUNDC1 PRKN PRKN ATG7 ATG7 ARFIP2 ARFIP2 L5KF67_PTEAL L5KF67_PTEAL PHB2 PHB2 L5L197_PTEAL L5L197_PTEAL GABARAPL1 GABARAPL1 ATG4D ATG4D L5L3C4_PTEAL L5L3C4_PTEAL L5L405_PTEAL L5L405_PTEAL WIPI1 WIPI1 WDR45B WDR45B ATG2A ATG2A L5KR03_PTEAL L5KR03_PTEAL ULK1 ULK1 L5KSP5_PTEAL L5KSP5_PTEAL GABARAPL2 GABARAPL2 L5KX86_PTEAL L5KX86_PTEAL OGT OGT L5KY23_PTEAL L5KY23_PTEAL MAP1LC3B MAP1LC3B L5JNT3_PTEAL L5JNT3_PTEAL ATG2B ATG2B FBXL4 FBXL4 BECN1 BECN1 TIGAR TIGAR SPATA33 SPATA33 PINK1 PINK1 WDR45 WDR45 ATG9A ATG9A L5JVG7_PTEAL L5JVG7_PTEAL SPATA18 SPATA18 GABARAP GABARAP USP30 USP30 GBA GBA SQSTM1 SQSTM1 MAP1LC3A MAP1LC3A TP53 TP53 CUNH5orf51 CUNH5orf51 L5K336_PTEAL L5K336_PTEAL SNX7 SNX7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG14Uncharacterized protein. (505 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
FUNDC1FUN14 domain-containing protein 1. (155 aa)
PRKNRBR-type E3 ubiquitin transferase. (128 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (743 aa)
ARFIP2Arfaptin-2. (341 aa)
L5KF67_PTEALE3 ubiquitin-protein ligase parkin. (131 aa)
PHB2Prohibitin. (278 aa)
L5L197_PTEALProtein FAM134B. (389 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (442 aa)
L5L3C4_PTEALFUN14 domain-containing protein 2. (189 aa)
L5L405_PTEALAutophagy-related protein 3. (336 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1. (437 aa)
WDR45BWD repeat domain phosphoinositide-interacting protein 3. (344 aa)
ATG2AAutophagy-related protein 2 like protein A. (998 aa)
L5KR03_PTEALAutophagy-related protein 2 like protein A. (942 aa)
ULK1Serine/threonine-protein kinase ULK1. (1072 aa)
L5KSP5_PTEALCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (431 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
L5KX86_PTEALActivating molecule in BECN1-regulated autophagy protein 1. (1209 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa)
L5KY23_PTEALAutophagy-related protein 13. (545 aa)
MAP1LC3BMicrotubule-associated proteins 1A/1B light chain 3B. (125 aa)
L5JNT3_PTEALAutophagy protein 5; Involved in autophagic vesicle formation. (216 aa)
ATG2BAutophagy-related protein 2 like protein B. (2078 aa)
FBXL4F-box/LRR-repeat protein 4. (603 aa)
BECN1Beclin-1. (470 aa)
TIGARPutative fructose-2,6-bisphosphatase TIGAR. (347 aa)
SPATA33Uncharacterized protein. (99 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (453 aa)
WDR45WD repeat domain phosphoinositide-interacting protein 4. (354 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (810 aa)
L5JVG7_PTEALRB1-inducible coiled-coil protein 1. (1407 aa)
SPATA18Spermatogenesis-associated protein 18. (644 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
GBAGlucosylceramidase. (536 aa)
SQSTM1Sequestosome-1. (64 aa)
MAP1LC3AMicrotubule-associated proteins 1A/1B light chain 3A. (121 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (378 aa)
CUNH5orf51Uncharacterized protein. (294 aa)
L5K336_PTEALAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa)
SNX7Sorting nexin-7. (473 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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