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ATG14 | Uncharacterized protein. (505 aa) | ||||
FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) | ||||
FUNDC1 | FUN14 domain-containing protein 1. (155 aa) | ||||
PRKN | RBR-type E3 ubiquitin transferase. (128 aa) | ||||
ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (743 aa) | ||||
ARFIP2 | Arfaptin-2. (341 aa) | ||||
L5KF67_PTEAL | E3 ubiquitin-protein ligase parkin. (131 aa) | ||||
PHB2 | Prohibitin. (278 aa) | ||||
L5L197_PTEAL | Protein FAM134B. (389 aa) | ||||
GABARAPL1 | Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa) | ||||
ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (442 aa) | ||||
L5L3C4_PTEAL | FUN14 domain-containing protein 2. (189 aa) | ||||
L5L405_PTEAL | Autophagy-related protein 3. (336 aa) | ||||
WIPI1 | WD repeat domain phosphoinositide-interacting protein 1. (437 aa) | ||||
WDR45B | WD repeat domain phosphoinositide-interacting protein 3. (344 aa) | ||||
ATG2A | Autophagy-related protein 2 like protein A. (998 aa) | ||||
L5KR03_PTEAL | Autophagy-related protein 2 like protein A. (942 aa) | ||||
ULK1 | Serine/threonine-protein kinase ULK1. (1072 aa) | ||||
L5KSP5_PTEAL | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (431 aa) | ||||
GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) | ||||
L5KX86_PTEAL | Activating molecule in BECN1-regulated autophagy protein 1. (1209 aa) | ||||
OGT | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa) | ||||
L5KY23_PTEAL | Autophagy-related protein 13. (545 aa) | ||||
MAP1LC3B | Microtubule-associated proteins 1A/1B light chain 3B. (125 aa) | ||||
L5JNT3_PTEAL | Autophagy protein 5; Involved in autophagic vesicle formation. (216 aa) | ||||
ATG2B | Autophagy-related protein 2 like protein B. (2078 aa) | ||||
FBXL4 | F-box/LRR-repeat protein 4. (603 aa) | ||||
BECN1 | Beclin-1. (470 aa) | ||||
TIGAR | Putative fructose-2,6-bisphosphatase TIGAR. (347 aa) | ||||
SPATA33 | Uncharacterized protein. (99 aa) | ||||
PINK1 | Serine/threonine-protein kinase PINK1, mitochondrial. (453 aa) | ||||
WDR45 | WD repeat domain phosphoinositide-interacting protein 4. (354 aa) | ||||
ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (810 aa) | ||||
L5JVG7_PTEAL | RB1-inducible coiled-coil protein 1. (1407 aa) | ||||
SPATA18 | Spermatogenesis-associated protein 18. (644 aa) | ||||
GABARAP | Gamma-aminobutyric acid receptor-associated protein. (117 aa) | ||||
USP30 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa) | ||||
GBA | Glucosylceramidase. (536 aa) | ||||
SQSTM1 | Sequestosome-1. (64 aa) | ||||
MAP1LC3A | Microtubule-associated proteins 1A/1B light chain 3A. (121 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (378 aa) | ||||
CUNH5orf51 | Uncharacterized protein. (294 aa) | ||||
L5K336_PTEAL | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa) | ||||
SNX7 | Sorting nexin-7. (473 aa) |