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| | SMG1 | Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family. (2981 aa) |
| | UFL1 | UPF0555 protein KIAA0776 like protein. (788 aa) |
| | L5JMI5_PTEAL | Sestrin-1. (608 aa) |
| | L5JMP7_PTEAL | Forkhead box protein O3. (248 aa) |
| | L5JMV1_PTEAL | Ras-related GTP-binding protein D. (420 aa) |
| | MAP6D1 | Presenilins-associated rhomboid-like protein, mitochondrial. (466 aa) |
| | L5JNG9_PTEAL | Transcription factor EB. (408 aa) |
| | TREML2 | Trem-like transcript 2 protein. (810 aa) |
| | L5JNT3_PTEAL | Autophagy protein 5; Involved in autophagic vesicle formation. (216 aa) |
| | USP10 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (797 aa) |
| | L5JP56_PTEAL | DUF4482 domain-containing protein. (692 aa) |
| | FOXO3 | Forkhead box protein O3. (479 aa) |
| | L5JPZ7_PTEAL | Signal transducer and activator of transcription. (714 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type-2 beta. (414 aa) |
| | L5JQJ1_PTEAL | Calcium-binding and coiled-coil domain-containing protein 2. (508 aa) |
| | UVRAG | UV radiation resistance-associated protein. (698 aa) |
| | MTMR4 | Myotubularin-related protein 4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (1644 aa) |
| | ATP6V0A1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (940 aa) |
| | SOGA3 | Uncharacterized protein. (947 aa) |
| | L5JRG5_PTEAL | Myotubularin-related protein 9. (406 aa) |
| | TMEM39B | Transmembrane protein 39B. (505 aa) |
| | L5JRI2_PTEAL | Ras-related GTP-binding protein C. (401 aa) |
| | BECN1 | Beclin-1. (470 aa) |
| | WAC | WW domain-containing adapter protein with coiled-coil. (643 aa) |
| | POLDIP2 | Polymerase delta-interacting protein 2. (367 aa) |
| | L5JSD0_PTEAL | Serine palmitoyltransferase 2. (529 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2. (479 aa) |
| | SESN2 | Sestrin-2. (480 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (363 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1. (729 aa) |
| | TIGAR | Putative fructose-2,6-bisphosphatase TIGAR. (347 aa) |
| | TRIM38 | Tripartite motif-containing protein 38. (496 aa) |
| | ZC3H12A | Ribonuclease ZC3H12A. (572 aa) |
| | L5JUP3_PTEAL | Myotubularin-related protein 9. (88 aa) |
| | TMEM173 | Transmembrane protein 173. (362 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1. (282 aa) |
| | L5JV44_PTEAL | Butyrophilin-like protein 9. (985 aa) |
| | PINK1 | Serine/threonine-protein kinase PINK1, mitochondrial. (453 aa) |
| | WDR45 | WD repeat domain phosphoinositide-interacting protein 4. (354 aa) |
| | L5JVG7_PTEAL | RB1-inducible coiled-coil protein 1. (1407 aa) |
| | L5JVN1_PTEAL | Dynamin-1-like protein. (192 aa) |
| | TBC1D25 | TBC1 domain family member 25. (687 aa) |
| | PHF23 | PHD finger protein 23. (419 aa) |
| | HDAC6 | Histone deacetylase 6. (1140 aa) |
| | L5JWS5_PTEAL | Ubiquilin-4. (571 aa) |
| | IL4 | Interleukin-4. (88 aa) |
| | TRIB3 | Tribbles like protein 3. (436 aa) |
| | L5JXR3_PTEAL | Tumor protein p53-inducible nuclear protein 2. (181 aa) |
| | L5JXV1_PTEAL | DUF4482 domain-containing protein. (1562 aa) |
| | IL10 | Interleukin-10. (178 aa) |
| | RALB | Ras-related protein Ral-B. (206 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (378 aa) |
| | BAG3 | BAG family molecular chaperone regulator 3. (544 aa) |
| | CTSA | Carboxypeptidase; Belongs to the peptidase S10 family. (494 aa) |
| | VPS13C | Vacuolar protein sorting-associated protein 13C. (3769 aa) |
| | L5K219_PTEAL | DUF4482 domain-containing protein. (1876 aa) |
| | RAB3GAP1 | Rab3 GTPase-activating protein catalytic subunit. (982 aa) |
| | L5K2A3_PTEAL | Sec1 family domain-containing protein 1; Belongs to the STXBP/unc-18/SEC1 family. (116 aa) |
| | ROCK1 | Rho-associated protein kinase 1; Belongs to the peptidase C19 family. (1791 aa) |
| | L5K2J1_PTEAL | Bcl-2-modifying factor. (215 aa) |
| | SNX7 | Sorting nexin-7. (473 aa) |
| | L5K3M0_PTEAL | Endophilin-B1. (394 aa) |
| | TMEM59 | Transmembrane protein 59. (334 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | ATG14 | Uncharacterized protein. (505 aa) |
| | L5K4F1_PTEAL | Phosphatidylinositol 3-kinase catalytic subunit type 3. (870 aa) |
| | L5K4F3_PTEAL | Leptin receptor. (888 aa) |
| | RMC1 | Uncharacterized protein. (610 aa) |
| | FBXW9 | F-box/WD repeat-containing protein 9. (457 aa) |
| | HTT | Huntingtin. (3210 aa) |
| | DCAF15 | DDB1-and CUL4-associated factor 15. (628 aa) |
| | L5K5C4_PTEAL | Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (215 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (462 aa) |
| | L5K6X0_PTEAL | TBC1 domain family member 14. (342 aa) |
| | NLRP6 | NACHT, LRR and PYD domains-containing protein 6. (734 aa) |
| | USP33 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (931 aa) |
| | L5K778_PTEAL | Myotubularin-related protein 8. (228 aa) |
| | TBC1D14 | TBC1 domain family member 14. (445 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | RRAGA | Ras-related GTP-binding protein A. (291 aa) |
| | LRRK2 | Leucine-rich repeat serine/threonine-protein kinase 2. (2496 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | ENDOG | Endonuclease. (302 aa) |
| | LRSAM1 | E3 ubiquitin-protein ligase LRSAM1. (708 aa) |
| | MTMR8 | Myotubularin-related protein 8. (501 aa) |
| | TP53INP1 | Tumor protein p53-inducible nuclear protein 1. (248 aa) |
| | L5KAV9_PTEAL | Major facilitator superfamily domain-containing protein 8. (342 aa) |
| | TRIML2 | Tripartite motif family-like protein 2. (490 aa) |
| | TRIM32 | Tripartite motif-containing protein 32. (653 aa) |
| | L5KBS2_PTEAL | WD repeat-containing protein 40C. (463 aa) |
| | RAB3GAP2 | Rab3 GTPase-activating protein non-catalytic subunit. (1399 aa) |
| | TRIM6 | Tripartite motif-containing protein 6. (481 aa) |
| | L5KCM1_PTEAL | Death-associated protein kinase 1. (593 aa) |
| | SIRT1 | NAD-dependent deacetylase sirtuin-1. (840 aa) |
| | CISD1 | CDGSH iron sulfur domain-containing protein 1. (140 aa) |
| | L5KDJ1_PTEAL | Tripartite motif family-like protein 1. (404 aa) |
| | L5KDJ9_PTEAL | Tripartite motif-containing protein 5. (391 aa) |
| | FEZ1 | Fasciculation and elongation protein zeta-1. (392 aa) |
| | DAPK1 | Death-associated protein kinase 1. (668 aa) |
| | L5KEI2_PTEAL | Ras-related GTP-binding protein B. (368 aa) |
| | HIF1A | Hypoxia-inducible factor 1 alpha. (873 aa) |
| | L5KF67_PTEAL | E3 ubiquitin-protein ligase parkin. (131 aa) |
| | L5KFR6_PTEAL | Serine/threonine-protein kinase mTOR. (457 aa) |
| | L5KFY8_PTEAL | Tripartite motif-containing protein 34. (495 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2208 aa) |
| | WDR24 | WD repeat-containing protein 24. (789 aa) |
| | PRKN | RBR-type E3 ubiquitin transferase. (128 aa) |
| | L5KGT3_PTEAL | Tuberin. (1802 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3; Belongs to the protein kinase superfamily. (410 aa) |
| | FYCO1 | FYVE and coiled-coil domain-containing protein 1. (1455 aa) |
| | MID2 | Midline-2. (676 aa) |
| | RNF152 | RING finger protein 152. (203 aa) |
| | SPTLC1 | Serine palmitoyltransferase 1. (473 aa) |
| | CLN3 | Battenin. (473 aa) |
| | RNF31 | RING finger protein 31. (1350 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1190 aa) |
| | L5KIA7_PTEAL | Uncharacterized protein. (425 aa) |
| | L5KIE0_PTEAL | Heme oxygenase 1. (262 aa) |
| | L5KIE2_PTEAL | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (2275 aa) |
| | WDR41 | WD repeat-containing protein 41. (457 aa) |
| | VPS13D | Vacuolar protein sorting-associated protein 13D. (4467 aa) |
| | NPRL3 | Uncharacterized protein. (570 aa) |
| | KAT8 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa) |
| | GPR137 | Integral membrane protein GPR137. (396 aa) |
| | PYCARD | Apoptosis-associated speck-like protein containing a CARD. (194 aa) |
| | PAFAH1B2 | Platelet-activating factor acetylhydrolase IB subunit beta. (234 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (217 aa) |
| | BNIP3 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (253 aa) |
| | DNM1L | Dynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (738 aa) |
| | L5KLD1_PTEAL | Tripartite motif-containing protein 65. (947 aa) |
| | SNX18 | Sorting nexin-18. (516 aa) |
| | L5KLR1_PTEAL | Nuclear receptor-binding protein. (748 aa) |
| | NOD1 | Nucleotide-binding oligomerization domain-containing protein 1. (92 aa) |
| | IL10RA | Interleukin-10 receptor alpha chain. (649 aa) |
| | L5KN37_PTEAL | Forkhead box protein K2. (369 aa) |
| | RPTOR | Regulatory-associated protein of mTOR. (1335 aa) |
| | SIRT2 | NAD-dependent deacetylase sirtuin-2. (451 aa) |
| | WIPI1 | WD repeat domain phosphoinositide-interacting protein 1. (437 aa) |
| | KDM4A | Lysine-specific demethylase 4A. (1061 aa) |
| | USP13 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (807 aa) |
| | CCNY | Cyclin-Y; Belongs to the cyclin family. (393 aa) |
| | L5KPK6_PTEAL | Two pore calcium channel protein 2. (872 aa) |
| | L5KPR2_PTEAL | Nucleotide-binding oligomerization domain-containing protein 1. (133 aa) |
| | ATG2A | Autophagy-related protein 2 like protein A. (998 aa) |
| | ERCC4 | DNA repair endonuclease XPF. (891 aa) |
| | L5KQL6_PTEAL | Protein CLEC16A. (1023 aa) |
| | L5KR03_PTEAL | Autophagy-related protein 2 like protein A. (942 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | L5KRI3_PTEAL | Serine/threonine-protein kinase SMG1. (782 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (146 aa) |
| | GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (432 aa) |
| | ULK1 | Serine/threonine-protein kinase ULK1. (1072 aa) |
| | FEZ2 | Fasciculation and elongation protein zeta-2. (362 aa) |
| | BOK | Bcl-2-related ovarian killer protein. (209 aa) |
| | SH3BP4 | SH3 domain-binding protein 4. (966 aa) |
| | WDR6 | WD repeat-containing protein 6. (1120 aa) |
| | NPRL2 | Tumor suppressor candidate 4. (380 aa) |
| | TRIM13 | Tripartite motif-containing protein 13. (338 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | L5KV42_PTEAL | Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma. (422 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2. (1017 aa) |
| | KLHL22 | Kelch-like protein 22. (650 aa) |
| | L5KVX2_PTEAL | Pleckstrin like proteiny domain-containing family F member 1. (302 aa) |
| | FLCN | Folliculin. (582 aa) |
| | FOXO1 | Forkhead box protein O1. (578 aa) |
| | TPCN1 | Two pore calcium channel protein 1. (836 aa) |
| | L5KX86_PTEAL | Activating molecule in BECN1-regulated autophagy protein 1. (1209 aa) |
| | SMCR8 | Smith-Magenis syndrome chromosomal region candidate protein 8 protein. (937 aa) |
| | TRIM27 | Zinc finger protein RFP. (496 aa) |
| | L5KY11_PTEAL | Cyclic AMP-dependent transcription factor ATF-6 alpha. (253 aa) |
| | L5KY23_PTEAL | Autophagy-related protein 13. (545 aa) |
| | L5KY75_PTEAL | Cyclic AMP-dependent transcription factor ATF-6 alpha. (614 aa) |
| | QSOX1 | Sulfhydryl oxidase. (685 aa) |
| | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4. (1380 aa) |
| | SESN3 | Sestrin-3. (492 aa) |
| | ATF6 | Cyclic AMP-dependent transcription factor ATF-6 alpha. (377 aa) |
| | L5L094_PTEAL | Serine/threonine-protein kinase D1. (243 aa) |
| | L5L0Q9_PTEAL | RUN and FYVE domain-containing protein 4. (177 aa) |
| | SCFD1 | Sec1 family domain-containing protein 1; Belongs to the STXBP/unc-18/SEC1 family. (661 aa) |
| | L5L137_PTEAL | Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha. (434 aa) |
| | CDK16 | Serine/threonine-protein kinase PCTAIRE-1; Belongs to the protein kinase superfamily. (496 aa) |
| | ATG16L1 | Autophagy-related protein 16-1. (608 aa) |
| | RUBCN | RUN domain-containing protein. (1016 aa) |
| | FBXW7 | F-box/WD repeat-containing protein 7. (629 aa) |
| | PRKD1 | Serine/threonine-protein kinase D1. (504 aa) |
| | MTMR9 | Myotubularin-related protein 9. (549 aa) |
| | RUFY4 | RUN and FYVE domain-containing protein 4. (146 aa) |
| | TRIM21 | 52 kDa Ro protein. (471 aa) |
| | RAB39B | Ras-related protein Rab-39B. (213 aa) |
| | SDK1 | Forkhead box protein K1. (1076 aa) |
| | L5L2L2_PTEAL | F-box/WD repeat-containing protein 7. (272 aa) |
| | L5L2L4_PTEAL | F-box/LRR-repeat protein 2. (385 aa) |
| | LARP1 | La-related protein 1. (949 aa) |
| | L5L317_PTEAL | Tectonin beta-propeller repeat-containing protein 1. (1198 aa) |
| | TMEM39A | Transmembrane protein 39A. (417 aa) |
| | SCOC | Short coiled-coil protein. (154 aa) |
| | L5L393_PTEAL | Sorting nexin-4. (317 aa) |
| | MTM1 | Myotubularin. (582 aa) |
| | KEAP1 | Kelch-like ECH-associated protein 1. (624 aa) |
| | XBP1 | X-box-binding protein 1. (264 aa) |
| | SUPT5H | Transcription elongation factor SPT5. (1083 aa) |
| | L5L5I6_PTEAL | DEP domain-containing protein 5. (1593 aa) |
| | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3. (1265 aa) |
| | MTMR3 | Myotubularin-related protein 3. (1194 aa) |
| | ATG101 | Autophagy-related protein 101. (218 aa) |
| | L5L6A1_PTEAL | Ras-interacting protein 1. (717 aa) |
| | CERS1 | LAG1 longevity assurance like protein 1. (239 aa) |
| | LZTS1 | Leucine zipper putative tumor suppressor 1. (500 aa) |
| | L5L757_PTEAL | Glycolipid transfer protein domain-containing protein 1. (259 aa) |
| | GSK3A | Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (415 aa) |
| | L5L7M9_PTEAL | Tripartite motif-containing protein 68. (237 aa) |
| | L5L7R6_PTEAL | Serine/threonine-protein kinase 11; Belongs to the protein kinase superfamily. (474 aa) |
| | L5L7V9_PTEAL | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (396 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (710 aa) |
| | L5L982_PTEAL | E3 ubiquitin-protein ligase TRIM50. (288 aa) |
| | KDR | Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1344 aa) |
