STRINGSTRING
PHB PHB AVPR1B AVPR1B PDGFRA PDGFRA RNASE4 RNASE4 FGF2 FGF2 HTR2A HTR2A ESR1 ESR1 PHB2 PHB2 L5KJR9_PTEAL L5KJR9_PTEAL L5KXU8_PTEAL L5KXU8_PTEAL PDGFRB PDGFRB ITK ITK NMUR1 NMUR1 ARHGAP6 ARHGAP6 L5L458_PTEAL L5L458_PTEAL L5L639_PTEAL L5L639_PTEAL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHBProhibitin. (272 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (430 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
RNASE4Ribonuclease 4; Belongs to the pancreatic ribonuclease family. (104 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (134 aa)
HTR2A5-hydroxytryptamine receptor 2A. (438 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (625 aa)
PHB2Prohibitin. (278 aa)
L5KJR9_PTEALAngiogenin; Belongs to the pancreatic ribonuclease family. (94 aa)
L5KXU8_PTEALTyrosine-protein kinase. (1060 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1125 aa)
ITKTyrosine-protein kinase. (620 aa)
NMUR1Neuromedin-U receptor 1; Belongs to the G-protein coupled receptor 1 family. (410 aa)
ARHGAP6Rho GTPase-activating protein 6. (742 aa)
L5L458_PTEALVascular endothelial growth factor receptor kdr-like protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1013 aa)
L5L639_PTEALVascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1247 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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