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| | VAMP8 | Vesicle-associated membrane protein 8. (100 aa) |
| | L5K8Z1_PTEAL | AP-4 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (428 aa) |
| | HDAC10 | Histone deacetylase 10. (679 aa) |
| | LAMP2 | Lysosome-associated membrane glycoprotein 2. (456 aa) |
| | TP53INP1 | Tumor protein p53-inducible nuclear protein 1. (248 aa) |
| | L5KAV9_PTEAL | Major facilitator superfamily domain-containing protein 8. (342 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (743 aa) |
| | L5JL23_PTEAL | Sorting nexin-14. (712 aa) |
| | UFL1 | UPF0555 protein KIAA0776 like protein. (788 aa) |
| | L5KBE5_PTEAL | Charged multivesicular body protein 1b-2. (241 aa) |
| | MCOLN1 | Mucolipin-1. (579 aa) |
| | VCP | Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (840 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | ARFIP2 | Arfaptin-2. (341 aa) |
| | ZFYVE26 | Zinc finger FYVE domain-containing protein 26. (2562 aa) |
| | L5KF67_PTEAL | E3 ubiquitin-protein ligase parkin. (131 aa) |
| | L5KFR6_PTEAL | Serine/threonine-protein kinase mTOR. (457 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2208 aa) |
| | PHB2 | Prohibitin. (278 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs like protein 1B. (194 aa) |
| | PRKN | RBR-type E3 ubiquitin transferase. (128 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3; Belongs to the protein kinase superfamily. (410 aa) |
| | CLN3 | Battenin. (473 aa) |
| | RUBCNL | DUF4206 domain-containing protein. (649 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1190 aa) |
| | MFN2 | Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (830 aa) |
| | L5KIE0_PTEAL | Heme oxygenase 1. (262 aa) |
| | L5KL32_PTEAL | Charged multivesicular body protein 6. (198 aa) |
| | LIX1 | Protein limb expression 1 like protein. (289 aa) |
| | ATG10 | Autophagy-related protein 10. (242 aa) |
| | NOD1 | Nucleotide-binding oligomerization domain-containing protein 1. (92 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (450 aa) |
| | GAA | Lysosomal alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. (926 aa) |
| | WIPI1 | WD repeat domain phosphoinositide-interacting protein 1. (437 aa) |
| | WDR45B | WD repeat domain phosphoinositide-interacting protein 3. (344 aa) |
| | L5KPM1_PTEAL | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (852 aa) |
| | L5KPR2_PTEAL | Nucleotide-binding oligomerization domain-containing protein 1. (133 aa) |
| | RAB1B | Ras-related protein Rab-1B. (247 aa) |
| | ATG2A | Autophagy-related protein 2 like protein A. (998 aa) |
| | STX17 | Syntaxin-17; Belongs to the syntaxin family. (311 aa) |
| | CTSD | Cathepsin D; Belongs to the peptidase A1 family. (375 aa) |
| | L5KR03_PTEAL | Autophagy-related protein 2 like protein A. (942 aa) |
| | UBXN2A | UBX domain-containing protein 2A. (295 aa) |
| | ULK1 | Serine/threonine-protein kinase ULK1. (1072 aa) |
| | PLEKHM1 | Pleckstrin like proteiny domain-containing family M member 1. (1062 aa) |
| | L5KSP5_PTEAL | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (431 aa) |
| | RAB1A | Ras-related protein Rab-1A. (197 aa) |
| | L5KT97_PTEAL | UBX domain-containing protein 2A. (96 aa) |
| | VPS33A | Vacuolar protein sorting-associated protein 33A; Belongs to the STXBP/unc-18/SEC1 family. (596 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1063 aa) |
| | TEX264 | Testis-expressed sequence 264 protein. (313 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2. (1017 aa) |
| | SNAP29 | Synaptosomal-associated protein 29. (258 aa) |
| | RAB7A | Ras-related protein Rab-7a. (207 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) |
| | L5KX86_PTEAL | Activating molecule in BECN1-regulated autophagy protein 1. (1209 aa) |
| | OGT | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa) |
| | PLAA | Phospholipase A-2-activating protein. (796 aa) |
| | L5KY23_PTEAL | Autophagy-related protein 13. (545 aa) |
| | WDFY3 | WD repeat and FYVE domain-containing protein 3. (3492 aa) |
| | STBD1 | Starch-binding domain-containing protein 1. (353 aa) |
| | CUNH6orf106 | N_BRCA1_IG domain-containing protein. (265 aa) |
| | UFC1 | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa) |
| | UBA5 | Ubiquitin-like modifier-activating enzyme 5. (404 aa) |
| | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4. (1380 aa) |
| | L5KZE7_PTEAL | DDRGK domain-containing protein 1. (77 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (810 aa) |
| | L5L0Q9_PTEAL | RUN and FYVE domain-containing protein 4. (177 aa) |
| | L5L137_PTEAL | Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha. (434 aa) |
| | L5L197_PTEAL | Protein FAM134B. (389 aa) |
| | ATG16L1 | Autophagy-related protein 16-1. (608 aa) |
| | RAB33B | Ras-related protein Rab-33B. (229 aa) |
| | GABARAPL1 | Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa) |
| | ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (442 aa) |
| | RUFY4 | RUN and FYVE domain-containing protein 4. (146 aa) |
| | L5L317_PTEAL | Tectonin beta-propeller repeat-containing protein 1. (1198 aa) |
| | MTM1 | Myotubularin. (582 aa) |
| | L5L405_PTEAL | Autophagy-related protein 3. (336 aa) |
| | TMEM41B | Transmembrane protein 41B. (265 aa) |
| | L5L4S9_PTEAL | Ancient ubiquitous protein 1. (363 aa) |
| | ATG101 | Autophagy-related protein 101. (218 aa) |
| | UBXN6 | UBX domain-containing protein 6. (437 aa) |
| | CHMP2A | Charged multivesicular body protein 2a. (229 aa) |
| | MAP1LC3B | Microtubule-associated proteins 1A/1B light chain 3B. (125 aa) |
| | CHMP2B | Charged multivesicular body protein 2b. (202 aa) |
| | L5JNT3_PTEAL | Autophagy protein 5; Involved in autophagic vesicle formation. (216 aa) |
| | ATG2B | Autophagy-related protein 2 like protein B. (2078 aa) |
| | L5JPV8_PTEAL | Ras-related protein Rab-23. (157 aa) |
| | L5JQ22_PTEAL | Next to BRCA1 protein 1 protein. (880 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type-2 beta. (414 aa) |
| | L5JQJ1_PTEAL | Calcium-binding and coiled-coil domain-containing protein 2. (508 aa) |
| | ZFYVE1 | Zinc finger FYVE domain-containing protein 1. (777 aa) |
| | UVRAG | UV radiation resistance-associated protein. (698 aa) |
| | WDR81 | WD repeat-containing protein 81. (1922 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (804 aa) |
| | RETREG3 | Protein FAM134C. (442 aa) |
| | BECN1 | Beclin-1. (470 aa) |
| | VMP1 | Transmembrane protein 49. (453 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2. (479 aa) |
| | TIGAR | Putative fructose-2,6-bisphosphatase TIGAR. (347 aa) |
| | SPATA33 | Uncharacterized protein. (99 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase SMURF1. (718 aa) |
| | TMEM173 | Transmembrane protein 173. (362 aa) |
| | STX12 | Syntaxin-12; Belongs to the syntaxin family. (275 aa) |
| | L5JUZ9_PTEAL | Ubiquitin thioesterase OTU1. (348 aa) |
| | UBXN2B | UBX domain-containing protein 2B. (332 aa) |
| | PINK1 | Serine/threonine-protein kinase PINK1, mitochondrial. (453 aa) |
| | WDR45 | WD repeat domain phosphoinositide-interacting protein 4. (354 aa) |
| | L5JVG7_PTEAL | RB1-inducible coiled-coil protein 1. (1407 aa) |
| | L5KB08_PTEAL | Charged multivesicular body protein 3. (236 aa) |
| | ULK3 | Serine/threonine-protein kinase ULK3; Belongs to the protein kinase superfamily. (471 aa) |
| | L5JWA7_PTEAL | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide; Belongs to the PI3/PI4-kinase family. (507 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | GABARAP | Gamma-aminobutyric acid receptor-associated protein. (117 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (844 aa) |
| | EMC6 | Transmembrane protein 93. (110 aa) |
| | CHMP1A | Charged multivesicular body protein 1a. (417 aa) |
| | L5JXR3_PTEAL | Tumor protein p53-inducible nuclear protein 2. (181 aa) |
| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide; Belongs to the PI3/PI4-kinase family. (1129 aa) |
| | SQSTM1 | Sequestosome-1. (64 aa) |
| | NSFL1C | NSFL1 cofactor p47. (370 aa) |
| | MAP1LC3A | Microtubule-associated proteins 1A/1B light chain 3A. (121 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (378 aa) |
| | PJVK | Pejvakin. (208 aa) |
| | L5K0K3_PTEAL | DDRGK domain-containing protein 1. (326 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs like protein 1A. (169 aa) |
| | LGALS8 | Galectin. (334 aa) |
| | L5K2I4_PTEAL | Vesicle transport through interaction with t-SNAREs like protein 1A. (65 aa) |
| | CUNH5orf51 | Uncharacterized protein. (294 aa) |
| | L5K336_PTEAL | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa) |
| | SNX7 | Sorting nexin-7. (473 aa) |
| | L5K3P6_PTEAL | Galectin. (186 aa) |
| | ATG14 | Uncharacterized protein. (505 aa) |
| | L5K4F1_PTEAL | Phosphatidylinositol 3-kinase catalytic subunit type 3. (870 aa) |
| | TRAPPC8 | Protein TRS85 like protein. (1435 aa) |
| | SPG11 | Spatacsin. (2447 aa) |
| | VPS39 | Vam6/Vps39-like protein. (869 aa) |
| | ATG16L2 | Autophagy-related protein 16-2. (622 aa) |
| | EPG5 | UPF0493 protein KIAA1632. (2815 aa) |
| | LIX1L | LIX1-like protein. (278 aa) |
| | L5K5U7_PTEAL | UPF0577 protein KIAA1324. (1011 aa) |
