27 items (Pteropus alecto) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L5KFM4_PTEAL	Adaptin ear-binding coat-associated protein 2. (298 aa)
	SLC18A3	Vesicular acetylcholine transporter. (529 aa)
	ENTHD1	ENTH domain-containing protein 1. (609 aa)
	AP1S1	AP-1 complex subunit sigma-1A. (401 aa)
	TCTEX1D1	SH3-containing GRB2-like protein 3-interacting protein 1. (916 aa)
	L5JVP5_PTEAL	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (91 aa)
	CLTB	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (155 aa)
	EPN3	Epsin-3. (257 aa)
	CLBA1	Clathrin_bdg domain-containing protein. (338 aa)
	AP2M1	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (433 aa)
	SYNRG	AP1 subunit gamma-binding protein 1. (1356 aa)
	L5JQN5_PTEAL	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1532 aa)
	AP2A1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (947 aa)
	CLINT1	Clathrin interactor 1. (643 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (174 aa)
	EPN2	Epsin-2. (200 aa)
	L5KX14_PTEAL	Epsin-2. (379 aa)
	L5KWA3_PTEAL	Epsin-2. (154 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1669 aa)
	L5KUQ6_PTEAL	Clathrin heavy chain linker domain-containing protein 1. (411 aa)
	AFTPH	Aftiphilin. (928 aa)
	L5KT27_PTEAL	AP-1 complex subunit gamma. (873 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (913 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
	AP1G2	AP-1 complex subunit gamma. (785 aa)
	NECAP1	Adaptin ear-binding coat-associated protein 1. (275 aa)
	L5KED1_PTEAL	Epsin-1. (475 aa)

Your Current Organism:

Pteropus alecto

NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFTPH	SYNRG	L5KT60	L5JQS5	Aftiphilin.	AP1 subunit gamma-binding protein 1.	0.495
AP1G2	AP1S1	L5KHS6	L5K6E5	AP-1 complex subunit gamma.	AP-1 complex subunit sigma-1A.	0.987
AP1G2	AP1S3	L5KHS6	L5L0I5	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.980
AP1G2	AP2A1	L5KHS6	L5L4G2	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.459
AP1G2	AP2M1	L5KHS6	L5JRJ0	AP-1 complex subunit gamma.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.862
AP1G2	CLINT1	L5KHS6	L5L106	AP-1 complex subunit gamma.	Clathrin interactor 1.	0.467
AP1G2	CLTA	L5KHS6	L5KP86	AP-1 complex subunit gamma.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.690
AP1G2	CLTB	L5KHS6	L5JV04	AP-1 complex subunit gamma.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.690
AP1G2	CLTCL1	L5KHS6	L5KVR0	AP-1 complex subunit gamma.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.831
AP1G2	ENTHD1	L5KHS6	L5K9G8	AP-1 complex subunit gamma.	ENTH domain-containing protein 1.	0.483
AP1G2	EPN2	L5KHS6	L5KXL4	AP-1 complex subunit gamma.	Epsin-2.	0.655
AP1G2	EPN3	L5KHS6	L5JTR7	AP-1 complex subunit gamma.	Epsin-3.	0.483
AP1G2	L5JQN5_PTEAL	L5KHS6	L5JQN5	AP-1 complex subunit gamma.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.831
AP1G2	L5JVP5_PTEAL	L5KHS6	L5JVP5	AP-1 complex subunit gamma.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.669
AP1G2	L5KED1_PTEAL	L5KHS6	L5KED1	AP-1 complex subunit gamma.	Epsin-1.	0.483
AP1G2	L5KFM4_PTEAL	L5KHS6	L5KFM4	AP-1 complex subunit gamma.	Adaptin ear-binding coat-associated protein 2.	0.581
AP1G2	L5KUQ6_PTEAL	L5KHS6	L5KUQ6	AP-1 complex subunit gamma.	Clathrin heavy chain linker domain-containing protein 1.	0.639
AP1G2	L5KWA3_PTEAL	L5KHS6	L5KWA3	AP-1 complex subunit gamma.	Epsin-2.	0.655
AP1G2	L5KX14_PTEAL	L5KHS6	L5KX14	AP-1 complex subunit gamma.	Epsin-2.	0.655
AP1G2	NECAP1	L5KHS6	L5KFW2	AP-1 complex subunit gamma.	Adaptin ear-binding coat-associated protein 1.	0.581