STRINGSTRING
GPR137 GPR137 LEP LEP L5KTX9_PTEAL L5KTX9_PTEAL SEH1L SEH1L GAS6 GAS6 KLHL22 KLHL22 FLCN FLCN WDR59 WDR59 SMCR8 SMCR8 PIH1D1 PIH1D1 GOLPH3 GOLPH3 NCKAP1L NCKAP1L L5K8N9_PTEAL L5K8N9_PTEAL PIP4P1 PIP4P1 LAMTOR1 LAMTOR1 L5KKL8_PTEAL L5KKL8_PTEAL RRAGA RRAGA LAMTOR4 LAMTOR4 RICTOR RICTOR LAMTOR5 LAMTOR5 L5K1X6_PTEAL L5K1X6_PTEAL L5K0P4_PTEAL L5K0P4_PTEAL RHEB RHEB WDR24 WDR24 LARS LARS L5JWK8_PTEAL L5JWK8_PTEAL OTUD5 OTUD5 HDAC3 HDAC3 FNIP1 FNIP1 LAMTOR2 LAMTOR2 L5JSY8_PTEAL L5JSY8_PTEAL WAC WAC L5JRI2_PTEAL L5JRI2_PTEAL L5JPI5_PTEAL L5JPI5_PTEAL TREML2 TREML2 L5JMV1_PTEAL L5JMV1_PTEAL TELO2 TELO2 L5KGG0_PTEAL L5KGG0_PTEAL L5KEI2_PTEAL L5KEI2_PTEAL SEC13 SEC13 L5KAM1_PTEAL L5KAM1_PTEAL L5KA61_PTEAL L5KA61_PTEAL L5KLX3_PTEAL L5KLX3_PTEAL RPTOR RPTOR L5KQL6_PTEAL L5KQL6_PTEAL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR137Integral membrane protein GPR137. (396 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (146 aa)
L5KTX9_PTEALGrowth arrest-specific protein 6. (77 aa)
SEH1LNucleoporin SEH1; Belongs to the WD repeat SEC13 family. (427 aa)
GAS6Growth arrest-specific protein 6. (640 aa)
KLHL22Kelch-like protein 22. (650 aa)
FLCNFolliculin. (582 aa)
WDR59WD repeat-containing protein 59. (968 aa)
SMCR8Smith-Magenis syndrome chromosomal region candidate protein 8 protein. (937 aa)
PIH1D1PIH1 domain-containing protein 1. (290 aa)
GOLPH3Golgi phosphoprotein 3. (299 aa)
NCKAP1LNck-associated protein 1-like protein. (1111 aa)
L5K8N9_PTEALPutative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2280 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
LAMTOR1Uncharacterized protein. (161 aa)
L5KKL8_PTEALPutative sodium-coupled neutral amino acid transporter 9. (412 aa)
RRAGARas-related GTP-binding protein A. (291 aa)
LAMTOR4Uncharacterized protein. (99 aa)
RICTORRapamycin-insensitive companion of mTOR. (1707 aa)
LAMTOR5Hepatitis B virus X-interacting protein like protein. (91 aa)
L5K1X6_PTEALUncharacterized protein. (63 aa)
L5K0P4_PTEALGTP-binding protein Rheb. (110 aa)
RHEBGTP-binding protein Rheb. (238 aa)
WDR24WD repeat-containing protein 24. (789 aa)
LARSLeucyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa)
L5JWK8_PTEALCystinosin. (290 aa)
OTUD5OTU domain-containing protein 5. (428 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
FNIP1Folliculin-interacting protein 1. (1138 aa)
LAMTOR2Mitogen-activated protein-binding protein-interacting protein. (125 aa)
L5JSY8_PTEALReelin. (105 aa)
WACWW domain-containing adapter protein with coiled-coil. (643 aa)
L5JRI2_PTEALRas-related GTP-binding protein C. (401 aa)
L5JPI5_PTEALReelin. (2633 aa)
TREML2Trem-like transcript 2 protein. (810 aa)
L5JMV1_PTEALRas-related GTP-binding protein D. (420 aa)
TELO2Telomere length regulation protein TEL2 like protein. (783 aa)
L5KGG0_PTEALTarget of rapamycin complex subunit LST8. (382 aa)
L5KEI2_PTEALRas-related GTP-binding protein B. (368 aa)
SEC13Protein SEC13 like protein; Belongs to the WD repeat SEC13 family. (432 aa)
L5KAM1_PTEALPutative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (666 aa)
L5KA61_PTEALPutative ubiquitin carboxyl-terminal hydrolase FAF-X. (1541 aa)
L5KLX3_PTEALWD repeat-containing protein mio. (830 aa)
RPTORRegulatory-associated protein of mTOR. (1335 aa)
L5KQL6_PTEALProtein CLEC16A. (1023 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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