(41 nodes) Positive regulation of insulin secretion network (Pteropus alecto)

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Your Input:
	TRH	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (243 aa)
	L5K7I5_PTEAL	Transcription factor 7-like 1. (236 aa)
	LRRC8A	Leucine-rich repeat-containing protein 8A. (810 aa)
	L5K2K2_PTEAL	Phosphatidylinositol-glycan-specific phospholipase D. (790 aa)
	L5K055_PTEAL	Transcription factor 7-like 2. (119 aa)
	FFAR1	Free fatty acid receptor 1. (301 aa)
	TCF7L2	Transcription factor 7-like 2. (399 aa)
	NLGN2	Neuroligin-2. (825 aa)
	L5JYL7_PTEAL	Neuronatin. (206 aa)
	L5JYI9_PTEAL	Transient receptor potential cation channel subfamily M member 2. (1211 aa)
	DOC2B	Double C2-like domain-containing protein beta. (473 aa)
	SRI	Sorcin. (198 aa)
	L5JPJ0_PTEAL	DNA-binding protein RFX6. (828 aa)
	GPR68	Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	BLK	Tyrosine-protein kinase. (495 aa)
	L5L2C9_PTEAL	Neuroligin-2. (186 aa)
	PRKCE	Protein kinase C; Belongs to the protein kinase superfamily. (497 aa)
	L5KUT2_PTEAL	Transcription factor SOX-4. (247 aa)
	CAPN10	Calpain-10; Belongs to the peptidase C2 family. (674 aa)
	L5KTD6_PTEAL	Protein kinase C epsilon type. (154 aa)
	L5KS66_PTEAL	Acetoacetyl-CoA synthetase. (699 aa)
	L5KR83_PTEAL	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1271 aa)
	L5KPK2_PTEAL	Anoctamin. (874 aa)
	GCK	Phosphotransferase. (588 aa)
	BAD	Bcl2 antagonist of cell death. (168 aa)
	L5KJ07_PTEAL	Adenylate cyclase type 8. (147 aa)
	ADCY8	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (746 aa)
	C2CD2L	C2 domain-containing protein 2-like protein. (706 aa)
	TM7SF3	Transmembrane 7 superfamily member 3. (570 aa)
	L5L917_PTEAL	Protein FAM132A. (306 aa)
	PDX1	Pancreas/duodenum homeobox protein 1. (317 aa)
	L5KJ98_PTEAL	Adenylate cyclase type 8. (423 aa)
	L5KHU8_PTEAL	Bile acid receptor. (472 aa)
	BAIAP3	BAI1-associated protein 3. (1130 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (507 aa)
	PLA2G6	85 kDa calcium-independent phospholipase A2. (752 aa)
	HIF1A	Hypoxia-inducible factor 1 alpha. (873 aa)
	GPER1	G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	L5KDC0_PTEAL	Uncharacterized protein. (144 aa)
	MCU	Coiled-coil domain-containing protein 109A. (297 aa)
	GHRL	Appetite-regulating hormone. (116 aa)

Your Current Organism:

Pteropus alecto

NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY8	L5KJ07_PTEAL	L5KM43	L5KJ07	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 8.	0.931
ADCY8	L5KJ98_PTEAL	L5KM43	L5KJ98	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 8.	0.730
BAD	PPP3CB	L5KNS7	L5KGB3	Bcl2 antagonist of cell death.	Serine/threonine-protein phosphatase.	0.911
CAPN10	SRI	L5KTY5	L5JPW3	Calpain-10; Belongs to the peptidase C2 family.	Sorcin.	0.447
GCK	L5JPJ0_PTEAL	L5KNY3	L5JPJ0	Phosphotransferase.	DNA-binding protein RFX6.	0.509
GCK	PDX1	L5KNY3	L5L5N0	Phosphotransferase.	Pancreas/duodenum homeobox protein 1.	0.700
GHRL	L5JPJ0_PTEAL	L5K8Q4	L5JPJ0	Appetite-regulating hormone.	DNA-binding protein RFX6.	0.455
GHRL	PDX1	L5K8Q4	L5L5N0	Appetite-regulating hormone.	Pancreas/duodenum homeobox protein 1.	0.476
GHRL	TRH	L5K8Q4	L5K895	Appetite-regulating hormone.	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	0.617
L5JPJ0_PTEAL	GCK	L5JPJ0	L5KNY3	DNA-binding protein RFX6.	Phosphotransferase.	0.509
L5JPJ0_PTEAL	GHRL	L5JPJ0	L5K8Q4	DNA-binding protein RFX6.	Appetite-regulating hormone.	0.455
L5JPJ0_PTEAL	PDX1	L5JPJ0	L5L5N0	DNA-binding protein RFX6.	Pancreas/duodenum homeobox protein 1.	0.457
L5K7I5_PTEAL	TCF7L2	L5K7I5	L5JZV0	Transcription factor 7-like 1.	Transcription factor 7-like 2.	0.436
L5KJ07_PTEAL	ADCY8	L5KJ07	L5KM43	Adenylate cyclase type 8.	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.931
L5KJ07_PTEAL	L5KJ98_PTEAL	L5KJ07	L5KJ98	Adenylate cyclase type 8.	Adenylate cyclase type 8.	0.871
L5KJ98_PTEAL	ADCY8	L5KJ98	L5KM43	Adenylate cyclase type 8.	Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.730
L5KJ98_PTEAL	L5KJ07_PTEAL	L5KJ98	L5KJ07	Adenylate cyclase type 8.	Adenylate cyclase type 8.	0.871
L5KPK2_PTEAL	L5KR83_PTEAL	L5KPK2	L5KR83	Anoctamin.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.532
L5KR83_PTEAL	L5KPK2_PTEAL	L5KR83	L5KPK2	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Anoctamin.	0.532
L5KR83_PTEAL	LRRC8A	L5KR83	L5K6B7	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Leucine-rich repeat-containing protein 8A.	0.445