STRINGSTRING
L5JM52_PTEAL L5JM52_PTEAL L5JQ28_PTEAL L5JQ28_PTEAL LHX1 LHX1 FOXF1 FOXF1 NLE1 NLE1 KAT2A KAT2A TCAP TCAP SEMA3C SEMA3C FRS2 FRS2 MYF5 MYF5 ZIC3 ZIC3 TIFAB TIFAB HES7 HES7 POFUT1 POFUT1 TP53 TP53 NRP2 NRP2 L5JZV5_PTEAL L5JZV5_PTEAL DVL2 DVL2 TDRD1 TDRD1 PAX1 PAX1 BMP4 BMP4 SMAD3 SMAD3 SMAD4 SMAD4 MIB1 MIB1 FOXB1 FOXB1 TDRKH TDRKH L5K3G8_PTEAL L5K3G8_PTEAL ALDH1A2 ALDH1A2 MTF2 MTF2 LEF1 LEF1 CRB2 CRB2 NRARP NRARP IRX2 IRX2 KDM6A KDM6A FAM208A FAM208A EP300 EP300 LFNG LFNG TAF10 TAF10 BMPR1A BMPR1A SFRP1 SFRP1 L5KEB6_PTEAL L5KEB6_PTEAL L5KEI8_PTEAL L5KEI8_PTEAL L5KFB1_PTEAL L5KFB1_PTEAL EGR2 EGR2 DLL1 DLL1 L5KIE2_PTEAL L5KIE2_PTEAL LRP6 LRP6 L5KK77_PTEAL L5KK77_PTEAL AXIN2 AXIN2 HOXA2 HOXA2 L5KMZ4_PTEAL L5KMZ4_PTEAL NKX3-1 NKX3-1 MEOX2 MEOX2 L5KPW6_PTEAL L5KPW6_PTEAL MSGN1 MSGN1 OSR1 OSR1 MEOX1 MEOX1 MED12 MED12 SEMA3F SEMA3F TBX3 TBX3 PLD6 PLD6 L5KXD4_PTEAL L5KXD4_PTEAL L5KY60_PTEAL L5KY60_PTEAL PLXNA2 PLXNA2 TDRD5 TDRD5 ABI1 ABI1 SFRP2 SFRP2 DLL3 DLL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L5JM52_PTEALMethenyltetrahydrofolate synthetase domain-containing protein. (411 aa)
L5JQ28_PTEALTudor domain-containing protein 6. (1243 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
FOXF1Forkhead box protein F1. (353 aa)
NLE1Notchless protein like protein 1. (513 aa)
KAT2AHistone acetyltransferase KAT2A. (860 aa)
TCAPTelethonin. (167 aa)
SEMA3CSemaphorin-3C; Belongs to the semaphorin family. (751 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
ZIC3Zinc finger protein ZIC 3. (469 aa)
TIFABTRAF-interacting protein with FHA domain-containing protein B. (201 aa)
HES7Transcription factor HES-7. (225 aa)
POFUT1GDP-fucose protein O-fucosyltransferase 1. (381 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (378 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
L5JZV5_PTEALNeuropilin-2. (138 aa)
DVL2Segment polarity protein dishevelled like protein DVL-2. (733 aa)
TDRD1Tudor domain-containing protein 1. (979 aa)
PAX1Paired box protein Pax-1. (408 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SMAD3Mothers against decapentaplegic homolog. (460 aa)
SMAD4Mothers against decapentaplegic homolog. (549 aa)
MIB1E3 ubiquitin-protein ligase MIB1. (1030 aa)
FOXB1Forkhead box protein B1. (325 aa)
TDRKHTudor and KH domain-containing protein. (575 aa)
L5K3G8_PTEALMothers against decapentaplegic like protein 3. (136 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
MTF2Metal-response element-binding transcription factor 2. (574 aa)
LEF1Lymphoid enhancer-binding factor 1. (451 aa)
CRB2Crumbs like protein 2. (771 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (165 aa)
IRX2Iroquois-class homeodomain protein IRX-2. (141 aa)
KDM6ALysine-specific demethylase 6A. (1142 aa)
FAM208ADUF3715 domain-containing protein. (1668 aa)
EP300Histone acetyltransferase p300. (2385 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (236 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
SFRP1Secreted frizzled-related protein 1. (283 aa)
L5KEB6_PTEALProtocadherin-8. (674 aa)
L5KEI8_PTEALBrachyury protein. (396 aa)
L5KFB1_PTEALProtocadherin-8. (302 aa)
EGR2Early growth response protein 2. (471 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (842 aa)
L5KIE2_PTEALSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (2275 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
L5KK77_PTEALT-box transcription factor TBX6. (409 aa)
AXIN2Axin-2. (783 aa)
HOXA2Homeobox protein Hox-A2. (373 aa)
L5KMZ4_PTEALProtein cordon-bleu. (364 aa)
NKX3-1Homeobox protein Nkx-3.1. (238 aa)
MEOX2Homeobox protein MOX-2. (208 aa)
L5KPW6_PTEALProtein cordon-bleu. (715 aa)
MSGN1Mesogenin-1. (194 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
MEOX1Homeobox protein MOX-1. (245 aa)
MED12Mediator of RNA polymerase II transcription subunit 12. (2236 aa)
SEMA3FSemaphorin-3F; Belongs to the semaphorin family. (803 aa)
TBX3T-box transcription factor TBX3. (746 aa)
PLD6Phospholipase D6. (161 aa)
L5KXD4_PTEALPlexin-A2. (298 aa)
L5KY60_PTEALPlexin-A2. (598 aa)
PLXNA2Plexin-A2. (1185 aa)
TDRD5Tudor domain-containing protein 5. (982 aa)
ABI1Abl interactor 1. (476 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
DLL3Delta-like protein 3. (254 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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