15 items (Pteropus alecto) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CUNH16orf70	Uncharacterized protein. (396 aa)
	L5JNT3_PTEAL	Autophagy protein 5; Involved in autophagic vesicle formation. (216 aa)
	ATG2B	Autophagy-related protein 2 like protein B. (2078 aa)
	WDR45	WD repeat domain phosphoinositide-interacting protein 4. (354 aa)
	L5K336_PTEAL	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa)
	ATG14	Uncharacterized protein. (505 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (743 aa)
	WIPI1	WD repeat domain phosphoinositide-interacting protein 1. (437 aa)
	WDR45B	WD repeat domain phosphoinositide-interacting protein 3. (344 aa)
	ATG2A	Autophagy-related protein 2 like protein A. (998 aa)
	L5KR03_PTEAL	Autophagy-related protein 2 like protein A. (942 aa)
	ULK1	Serine/threonine-protein kinase ULK1. (1072 aa)
	ULK2	Serine/threonine-protein kinase ULK2. (1641 aa)
	ATG9A	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (810 aa)
	ATG101	Autophagy-related protein 101. (218 aa)

Your Current Organism:

Pteropus alecto

NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG101	ATG14	L5L5W2	L5K434	Autophagy-related protein 101.	Uncharacterized protein.	0.988
ATG101	ATG2A	L5L5W2	L5KQA6	Autophagy-related protein 101.	Autophagy-related protein 2 like protein A.	0.445
ATG101	ATG7	L5L5W2	L5KAW1	Autophagy-related protein 101.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.599
ATG101	ATG9A	L5L5W2	L5L0M2	Autophagy-related protein 101.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.589
ATG101	CUNH16orf70	L5L5W2	L5KUK1	Autophagy-related protein 101.	Uncharacterized protein.	0.454
ATG101	L5JNT3_PTEAL	L5L5W2	L5JNT3	Autophagy-related protein 101.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.640
ATG101	L5K336_PTEAL	L5L5W2	L5K336	Autophagy-related protein 101.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.407
ATG101	L5KR03_PTEAL	L5L5W2	L5KR03	Autophagy-related protein 101.	Autophagy-related protein 2 like protein A.	0.445
ATG101	ULK1	L5L5W2	L5KS11	Autophagy-related protein 101.	Serine/threonine-protein kinase ULK1.	0.997
ATG101	ULK2	L5L5W2	L5KW91	Autophagy-related protein 101.	Serine/threonine-protein kinase ULK2.	0.998
ATG101	WDR45B	L5L5W2	L5KNK1	Autophagy-related protein 101.	WD repeat domain phosphoinositide-interacting protein 3.	0.451
ATG101	WIPI1	L5L5W2	L5KNI1	Autophagy-related protein 101.	WD repeat domain phosphoinositide-interacting protein 1.	0.481
ATG14	ATG101	L5K434	L5L5W2	Uncharacterized protein.	Autophagy-related protein 101.	0.988
ATG14	ATG2A	L5K434	L5KQA6	Uncharacterized protein.	Autophagy-related protein 2 like protein A.	0.448
ATG14	ATG2B	L5K434	L5JP36	Uncharacterized protein.	Autophagy-related protein 2 like protein B.	0.507
ATG14	ATG7	L5K434	L5KAW1	Uncharacterized protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.680
ATG14	ATG9A	L5K434	L5L0M2	Uncharacterized protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.803
ATG14	CUNH16orf70	L5K434	L5KUK1	Uncharacterized protein.	Uncharacterized protein.	0.420
ATG14	L5JNT3_PTEAL	L5K434	L5JNT3	Uncharacterized protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.869
ATG14	L5K336_PTEAL	L5K434	L5K336	Uncharacterized protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.586