STRINGSTRING
GRIN2B GRIN2B L5KLL4_PTEAL L5KLL4_PTEAL PTK2 PTK2 SDC2 SDC2 ACTG1 ACTG1 EPHB6 EPHB6 CFL1 CFL1 ROCK2 ROCK2 FNDC3B FNDC3B EPHB4 EPHB4 L5K8U0_PTEAL L5K8U0_PTEAL GRIN1 GRIN1 ARPC5L ARPC5L L5K518_PTEAL L5K518_PTEAL ROCK1 ROCK1 ITSN1 ITSN1 L5KBS6_PTEAL L5KBS6_PTEAL FNDC3A FNDC3A ACTL8 ACTL8 CFL2 CFL2 WASL WASL ACTR2 ACTR2 L5KXJ3_PTEAL L5KXJ3_PTEAL EFNB1 EFNB1 L5KY80_PTEAL L5KY80_PTEAL L5L0Y3_PTEAL L5L0Y3_PTEAL GPBAR1 GPBAR1 ACTB ACTB L5L4Y5_PTEAL L5L4Y5_PTEAL LIMK2 LIMK2 L5K1K2_PTEAL L5K1K2_PTEAL L5K146_PTEAL L5K146_PTEAL ACTR3B ACTR3B EFNB3 EFNB3 ACTR3 ACTR3 L5JYI5_PTEAL L5JYI5_PTEAL FMN2 FMN2 CDC42 CDC42 L5JS75_PTEAL L5JS75_PTEAL EPHB2 EPHB2 PAK1 PAK1 EPHB3 EPHB3 efnB2 efnB2 L5KIG0_PTEAL L5KIG0_PTEAL RASA1 RASA1 L5KJ38_PTEAL L5KJ38_PTEAL L5KJC7_PTEAL L5KJC7_PTEAL ARPC1A ARPC1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIN2BGlutamate [NMDA] receptor subunit epsilon-2. (1355 aa)
L5KLL4_PTEALFocal adhesion kinase 1. (220 aa)
PTK2Focal adhesion kinase 1. (387 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (226 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
EPHB6Ephrin type-B receptor 6. (1006 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (178 aa)
ROCK2Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1480 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1158 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
L5K8U0_PTEALActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (83 aa)
GRIN1Glutamate [NMDA] receptor subunit zeta-1. (878 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (101 aa)
L5K518_PTEALFormin-1. (1186 aa)
ROCK1Rho-associated protein kinase 1; Belongs to the peptidase C19 family. (1791 aa)
ITSN1Intersectin-1. (1376 aa)
L5KBS6_PTEALFibronectin type III domain containing 3c. (1573 aa)
FNDC3AFibronectin type-III domain-containing protein 3a. (1198 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (178 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (501 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
L5KXJ3_PTEALActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (203 aa)
EFNB1Ephrin-B1; Belongs to the ephrin family. (347 aa)
L5KY80_PTEALT-lymphoma invasion and metastasis-inducing protein 1. (1024 aa)
L5L0Y3_PTEALEphrin type-B receptor 1. (847 aa)
GPBAR1Actin-related protein 2/3 complex subunit 2. (677 aa)
ACTBActin, cytoplasmic 1. (375 aa)
L5L4Y5_PTEALKalirin. (340 aa)
LIMK2LIM domain kinase 2. (638 aa)
L5K1K2_PTEALFormin-1. (615 aa)
L5K146_PTEALUnhealthy ribosome biogenesis protein 2 like protein. (133 aa)
ACTR3BActin-related protein 3B; Belongs to the actin family. (457 aa)
EFNB3Ephrin-B3; Belongs to the ephrin family. (340 aa)
ACTR3Actin-related protein 3; Belongs to the actin family. (418 aa)
L5JYI5_PTEALIntersectin-1. (365 aa)
FMN2Formin-2. (1070 aa)
CDC42Cell division control protein 42 like protein. (295 aa)
L5JS75_PTEALEphrin type-B receptor 2. (290 aa)
EPHB2Ephrin type-B receptor 2. (707 aa)
PAK1Non-specific serine/threonine protein kinase. (1101 aa)
EPHB3Ephrin type-B receptor 3. (1124 aa)
efnB2Ephrin-B2; Belongs to the ephrin family. (333 aa)
L5KIG0_PTEALRho-guanine nucleotide exchange factor. (1692 aa)
RASA1Ras GTPase-activating protein 1. (1041 aa)
L5KJ38_PTEALFocal adhesion kinase 1. (346 aa)
L5KJC7_PTEALFocal adhesion kinase 1. (454 aa)
ARPC1AActin-related protein 2/3 complex subunit 1A. (789 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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