STRINGSTRING
ENTHD1 ENTHD1 EPS15L1 EPS15L1 SH3GL1 SH3GL1 L5L6X9_PTEAL L5L6X9_PTEAL L5L6V3_PTEAL L5L6V3_PTEAL KXD1 KXD1 SH3GL3 SH3GL3 L5L4Q0_PTEAL L5L4Q0_PTEAL AP2A1 AP2A1 L5L4F8_PTEAL L5L4F8_PTEAL TACR1 TACR1 L5L3S4_PTEAL L5L3S4_PTEAL VAMP7 VAMP7 LDLR LDLR AGFG1 AGFG1 SYT9 SYT9 COPS7B COPS7B L5KZX6_PTEAL L5KZX6_PTEAL STAM STAM EREG EREG AREG AREG L5KZ19_PTEAL L5KZ19_PTEAL GPR52 GPR52 COPS4 COPS4 SYT2 SYT2 BMP2K BMP2K L5KY00_PTEAL L5KY00_PTEAL ARR3 ARR3 EPN2 EPN2 L5KX14_PTEAL L5KX14_PTEAL COPS3 COPS3 L5KWC8_PTEAL L5KWC8_PTEAL L5KWA3_PTEAL L5KWA3_PTEAL CLTCL1 CLTCL1 NETO2 NETO2 L5KUZ1_PTEAL L5KUZ1_PTEAL L5KUQ6_PTEAL L5KUQ6_PTEAL STON1 STON1 TGFA TGFA UBC UBC L5KTJ3_PTEAL L5KTJ3_PTEAL ITSN2 ITSN2 CHRM2 CHRM2 COPS8 COPS8 UBQLN2 UBQLN2 L5KRN9_PTEAL L5KRN9_PTEAL L5KRF5_PTEAL L5KRF5_PTEAL L5KRE2_PTEAL L5KRE2_PTEAL L5KR83_PTEAL L5KR83_PTEAL GRK2 GRK2 EGFR EGFR SH3KBP1 SH3KBP1 L5KPG4_PTEAL L5KPG4_PTEAL AP2A2 AP2A2 CLTA CLTA L5KNA4_PTEAL L5KNA4_PTEAL L5KMQ4_PTEAL L5KMQ4_PTEAL L5KM65_PTEAL L5KM65_PTEAL L5KLN0_PTEAL L5KLN0_PTEAL FCHO2 FCHO2 GRB2 GRB2 HGS HGS L5KKR8_PTEAL L5KKR8_PTEAL CD3G CD3G L5KJL1_PTEAL L5KJL1_PTEAL L5KHR5_PTEAL L5KHR5_PTEAL REPS1 REPS1 M6PR M6PR L5KFZ8_PTEAL L5KFZ8_PTEAL NECAP1 NECAP1 VAMP3 VAMP3 L5KFM4_PTEAL L5KFM4_PTEAL L5KFG2_PTEAL L5KFG2_PTEAL IGF2R IGF2R UBQLNL UBQLNL L5KED1_PTEAL L5KED1_PTEAL UBQLN3 UBQLN3 AVPR2 AVPR2 SLC18A3 SLC18A3 UBQLN1 UBQLN1 VAMP5 VAMP5 TOR1A TOR1A AGFG2 AGFG2 SLC2A8 SLC2A8 AGTR1 AGTR1 VAMP8 VAMP8 IL7R IL7R TOR1B TOR1B L5K6M6_PTEAL L5K6M6_PTEAL COPS6 COPS6 EPS15 EPS15 SH3GL2 SH3GL2 CLPB CLPB L5K4Y3_PTEAL L5K4Y3_PTEAL L5K4Y1_PTEAL L5K4Y1_PTEAL COPS2 COPS2 L5K3Z4_PTEAL L5K3Z4_PTEAL TCTEX1D1 TCTEX1D1 DAB2 DAB2 STAM2 STAM2 ITSN1 ITSN1 SYT4 SYT4 ADRB1 ADRB1 L5K006_PTEAL L5K006_PTEAL DVL2 DVL2 L5JYI5_PTEAL L5JYI5_PTEAL ARRB2 ARRB2 L5JWS5_PTEAL L5JWS5_PTEAL L5JVP5_PTEAL L5JVP5_PTEAL L5JVM5_PTEAL L5JVM5_PTEAL SYT1 SYT1 HBEGF HBEGF CLTB CLTB LDLRAP1 LDLRAP1 MCTP2 MCTP2 KIAA0319L KIAA0319L SYT11 SYT11 EPN3 EPN3 L5JTD9_PTEAL L5JTD9_PTEAL COPS5 COPS5 AP2M1 AP2M1 L5JQT4_PTEAL L5JQT4_PTEAL L5JQR9_PTEAL L5JQR9_PTEAL L5JQP3_PTEAL L5JQP3_PTEAL L5JQN5_PTEAL L5JQN5_PTEAL ARRB1 ARRB1 ZFYVE1 ZFYVE1 L5JPN4_PTEAL L5JPN4_PTEAL L5JMY0_PTEAL L5JMY0_PTEAL FZD4 FZD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENTHD1ENTH domain-containing protein 1. (609 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1. (929 aa)
SH3GL1Endophilin-A2. (333 aa)
L5L6X9_PTEAL60S ribosomal protein L40. (74 aa)
L5L6V3_PTEALFCH domain only protein 1. (746 aa)
KXD1KxDL domain-containing protein. (176 aa)
SH3GL3Endophilin-A3. (278 aa)
L5L4Q0_PTEALG protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (640 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (947 aa)
L5L4F8_PTEALAP-1 complex subunit beta-1. (152 aa)
TACR1Substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
L5L3S4_PTEALPhosphatidylinositol-binding clathrin assembly protein. (166 aa)
VAMP7Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (392 aa)
LDLRLow-density lipoprotein receptor. (881 aa)
AGFG1Arf-GAP domain and FG repeat-containing protein 1. (538 aa)
SYT9Synaptotagmin-9. (502 aa)
COPS7BCOP9 signalosome complex subunit 7b. (264 aa)
L5KZX6_PTEALInhibitor of carbonic anhydrase; Belongs to the transferrin family. (636 aa)
STAMSignal transducing adapter molecule 1. (599 aa)
EREGEpigen. (134 aa)
AREGAmphiregulin. (282 aa)
L5KZ19_PTEALSerotransferrin; Belongs to the transferrin family. (707 aa)
GPR52Putative G-protein coupled receptor 52; Belongs to the G-protein coupled receptor 1 family. (361 aa)
COPS4COP9 signalosome complex subunit 4. (406 aa)
SYT2Synaptotagmin-2. (418 aa)
BMP2KBMP-2-inducible protein kinase. (1146 aa)
L5KY00_PTEALVesicle-associated membrane protein 4. (164 aa)
ARR3Arrestin-C. (361 aa)
EPN2Epsin-2. (200 aa)
L5KX14_PTEALEpsin-2. (379 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
L5KWC8_PTEALUbiquitin. (77 aa)
L5KWA3_PTEALEpsin-2. (154 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1669 aa)
NETO2Neuropilin and tolloid-like protein 2. (528 aa)
L5KUZ1_PTEALAP2-associated protein kinase 1. (1334 aa)
L5KUQ6_PTEALClathrin heavy chain linker domain-containing protein 1. (411 aa)
STON1TFIIA-alpha and beta-like factor; Belongs to the Stoned B family. (808 aa)
TGFAProtransforming growth factor alpha. (300 aa)
UBCUbiquitin. (381 aa)
L5KTJ3_PTEALAP-2 complex subunit beta. (151 aa)
ITSN2Intersectin-2. (1208 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
COPS8COP9 signalosome complex subunit 8. (209 aa)
UBQLN2Ubiquilin-2. (624 aa)
L5KRN9_PTEALAP-1 complex subunit beta-1. (52 aa)
L5KRF5_PTEALIntersectin-2. (488 aa)
L5KRE2_PTEALApolipoprotein B-100. (4317 aa)
L5KR83_PTEALCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1271 aa)
GRK2Beta-adrenergic receptor kinase 1. (1209 aa)
EGFREpidermal growth factor receptor. (850 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1. (720 aa)
L5KPG4_PTEALSynaptotagmin-8. (369 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (913 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
L5KNA4_PTEALE3 ubiquitin-protein ligase CBL. (909 aa)
L5KMQ4_PTEALRalBP1-associated Eps domain-containing protein 2. (611 aa)
L5KM65_PTEALT-cell surface glycoprotein CD3 delta chain. (93 aa)
L5KLN0_PTEALCOP9 signalosome complex subunit 1. (556 aa)
FCHO2FCH domain only protein 2. (916 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (590 aa)
L5KKR8_PTEALHepatocyte growth factor-regulated tyrosine kinase substrate. (206 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (184 aa)
L5KJL1_PTEALMultiple C2 and transmembrane domain-containing protein 1. (795 aa)
L5KHR5_PTEALNeuropilin and tolloid-like protein 1. (611 aa)
REPS1RalBP1-associated Eps domain-containing protein 1. (796 aa)
M6PRCation-dependent mannose-6-phosphate receptor. (278 aa)
L5KFZ8_PTEALUbiquilin-1. (507 aa)
NECAP1Adaptin ear-binding coat-associated protein 1. (275 aa)
VAMP3Vesicle-associated membrane protein 3. (149 aa)
L5KFM4_PTEALAdaptin ear-binding coat-associated protein 2. (298 aa)
L5KFG2_PTEALT-cell surface glycoprotein CD4. (375 aa)
IGF2RCation-independent mannose-6-phosphate receptor. (2471 aa)
UBQLNLUbiquilin-like protein. (594 aa)
L5KED1_PTEALEpsin-1. (475 aa)
UBQLN3Ubiquilin-3. (650 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (362 aa)
SLC18A3Vesicular acetylcholine transporter. (529 aa)
UBQLN1Ubiquilin-1. (589 aa)
VAMP5Vesicle-associated membrane protein 5. (97 aa)
TOR1ATorsin-1A. (382 aa)
AGFG2Arf-GAP domain and FG repeat-containing protein 2. (488 aa)
SLC2A8Solute carrier family 2, facilitated glucose transporter member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (478 aa)
AGTR1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
VAMP8Vesicle-associated membrane protein 8. (100 aa)
IL7RInterleukin-7 receptor subunit alpha. (459 aa)
TOR1BTorsin-1B. (215 aa)
L5K6M6_PTEALPro-epidermal growth factor. (991 aa)
COPS6COP9 signalosome complex subunit 6. (324 aa)
EPS15Epidermal growth factor receptor substrate 15. (1196 aa)
SH3GL2Endophilin-A1. (357 aa)
CLPBCaseinolytic peptidase B protein like protein. (425 aa)
L5K4Y3_PTEALCaseinolytic peptidase B protein like protein. (262 aa)
L5K4Y1_PTEALZinc finger FYVE domain-containing protein 19. (356 aa)
COPS2COP9 signalosome complex subunit 2. (446 aa)
L5K3Z4_PTEALLMBR1 domain-containing protein 2. (667 aa)
TCTEX1D1SH3-containing GRB2-like protein 3-interacting protein 1. (916 aa)
DAB2Disabled like protein 2. (733 aa)
STAM2Signal transducing adapter molecule 2. (495 aa)
ITSN1Intersectin-1. (1376 aa)
SYT4Synaptotagmin-4. (461 aa)
ADRB1Beta-1 adrenergic receptor. (460 aa)
L5K006_PTEALLow-density lipoprotein receptor-related protein 2. (4395 aa)
DVL2Segment polarity protein dishevelled like protein DVL-2. (733 aa)
L5JYI5_PTEALIntersectin-1. (365 aa)
ARRB2Beta-arrestin-2. (409 aa)
L5JWS5_PTEALUbiquilin-4. (571 aa)
L5JVP5_PTEALClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (91 aa)
L5JVM5_PTEALUbiquitin-like protein 7. (380 aa)
SYT1Synaptotagmin-1. (423 aa)
HBEGFProheparin-binding EGF-like growth factor. (210 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (155 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (264 aa)
MCTP2Multiple C2 and transmembrane domain-containing protein 2. (545 aa)
KIAA0319LUncharacterized protein. (1089 aa)
SYT11Synaptotagmin-11. (373 aa)
EPN3Epsin-3. (257 aa)
L5JTD9_PTEALMultiple C2 and transmembrane domain-containing protein 2. (445 aa)
COPS5COP9 signalosome complex subunit 5. (334 aa)
AP2M1AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (433 aa)
L5JQT4_PTEALAP complex subunit beta. (1042 aa)
L5JQR9_PTEALStonin-2; Belongs to the Stoned B family. (895 aa)
L5JQP3_PTEALPhosphatidylinositol-binding clathrin assembly protein. (688 aa)
L5JQN5_PTEALClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1532 aa)
ARRB1Beta-arrestin-1. (413 aa)
ZFYVE1Zinc finger FYVE domain-containing protein 1. (777 aa)
L5JPN4_PTEALUbiquilin-1. (519 aa)
L5JMY0_PTEALClathrin coat assembly protein AP180. (800 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (479 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
Server load: low (12%) [HD]