STRINGSTRING
L5KI92_PTEAL L5KI92_PTEAL ATP6V1D ATP6V1D WDR24 WDR24 L5KGG0_PTEAL L5KGG0_PTEAL MTOR MTOR L5KFR6_PTEAL L5KFR6_PTEAL L5KEI2_PTEAL L5KEI2_PTEAL RHEBL1 RHEBL1 ATF4 ATF4 SEC13 SEC13 ATP6V1C1 ATP6V1C1 L5K9V4_PTEAL L5K9V4_PTEAL FNIP2 FNIP2 ATP6V1G1 ATP6V1G1 LAMTOR1 LAMTOR1 DMRT2 DMRT2 RRAGA RRAGA LAMTOR4 LAMTOR4 L5K6Q4_PTEAL L5K6Q4_PTEAL DMRT3 DMRT3 L5K654_PTEAL L5K654_PTEAL LAMTOR5 LAMTOR5 L5K3K1_PTEAL L5K3K1_PTEAL CRYGN CRYGN L5K1X6_PTEAL L5K1X6_PTEAL IMPACT IMPACT EIF2AK4 EIF2AK4 L5K0P4_PTEAL L5K0P4_PTEAL RHEB RHEB ATP6V1E1 ATP6V1E1 ITFG2 ITFG2 L5JVX4_PTEAL L5JVX4_PTEAL CUNH12orf66 CUNH12orf66 FNIP1 FNIP1 LAMTOR2 LAMTOR2 METTL25 METTL25 ATP6V1H ATP6V1H SESN2 SESN2 L5JRI2_PTEAL L5JRI2_PTEAL L5JMV1_PTEAL L5JMV1_PTEAL L5JMI5_PTEAL L5JMI5_PTEAL CEBPG CEBPG RPS19 RPS19 L5L6E4_PTEAL L5L6E4_PTEAL KPTN KPTN ATP6V1B2 ATP6V1B2 L5L5I6_PTEAL L5L5I6_PTEAL CASTOR1 CASTOR1 CRYBB3 CRYBB3 L5L553_PTEAL L5L553_PTEAL L5L4F3_PTEAL L5L4F3_PTEAL LIM2 LIM2 L5L194_PTEAL L5L194_PTEAL ATF3 ATF3 L5KYI0_PTEAL L5KYI0_PTEAL DMRTA1 DMRTA1 WDR59 WDR59 GCN1 GCN1 L5KWV4_PTEAL L5KWV4_PTEAL FLCN FLCN DDIT3 DDIT3 NPRL2 NPRL2 ATP6V1B1 ATP6V1B1 SEH1L SEH1L ATP6V0D1 ATP6V0D1 SH3BP4 SH3BP4 ATP6V1E2 ATP6V1E2 PPP1R3A PPP1R3A BMT2 BMT2 L5KRW5_PTEAL L5KRW5_PTEAL ATP6V1F ATP6V1F L5KRC6_PTEAL L5KRC6_PTEAL L5KPM1_PTEAL L5KPM1_PTEAL MACC1 MACC1 ATP6V0B ATP6V0B RPTOR RPTOR SZT2 SZT2 L5KLX3_PTEAL L5KLX3_PTEAL L5KKL8_PTEAL L5KKL8_PTEAL NPRL3 NPRL3 CNST CNST ATP6V0C ATP6V0C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L5KI92_PTEALCyclic AMP-dependent transcription factor ATF-4. (215 aa)
ATP6V1DV-type proton ATPase subunit D. (247 aa)
WDR24WD repeat-containing protein 24. (789 aa)
L5KGG0_PTEALTarget of rapamycin complex subunit LST8. (382 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2208 aa)
L5KFR6_PTEALSerine/threonine-protein kinase mTOR. (457 aa)
L5KEI2_PTEALRas-related GTP-binding protein B. (368 aa)
RHEBL1GTPase RhebL1. (183 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
SEC13Protein SEC13 like protein; Belongs to the WD repeat SEC13 family. (432 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
L5K9V4_PTEALFolliculin-interacting protein 2. (880 aa)
FNIP2Folliculin-interacting protein 2. (320 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
LAMTOR1Uncharacterized protein. (161 aa)
DMRT2Doublesex-and mab-3-related transcription factor 2. (561 aa)
RRAGARas-related GTP-binding protein A. (291 aa)
LAMTOR4Uncharacterized protein. (99 aa)
L5K6Q4_PTEALDoublesex-and mab-3-related transcription factor B1. (309 aa)
DMRT3Doublesex-and mab-3-related transcription factor 3. (471 aa)
L5K654_PTEALGATS-like protein 2. (350 aa)
LAMTOR5Hepatitis B virus X-interacting protein like protein. (91 aa)
L5K3K1_PTEALDoublesex-and mab-3-related transcription factor A2. (215 aa)
CRYGNGamma-crystallin N; Belongs to the beta/gamma-crystallin family. (148 aa)
L5K1X6_PTEALUncharacterized protein. (63 aa)
IMPACTProtein IMPACT. (318 aa)
EIF2AK4Eukaryotic translation initiation factor 2-alpha kinase 4. (1642 aa)
L5K0P4_PTEALGTP-binding protein Rheb. (110 aa)
RHEBGTP-binding protein Rheb. (238 aa)
ATP6V1E1V-type proton ATPase subunit E 1. (226 aa)
ITFG2Integrin-alpha FG-GAP repeat-containing protein 2. (444 aa)
L5JVX4_PTEALV-type proton ATPase subunit d 2. (324 aa)
CUNH12orf66Uncharacterized protein. (398 aa)
FNIP1Folliculin-interacting protein 1. (1138 aa)
LAMTOR2Mitogen-activated protein-binding protein-interacting protein. (125 aa)
METTL25Methyltranfer_dom domain-containing protein. (724 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (443 aa)
SESN2Sestrin-2. (480 aa)
L5JRI2_PTEALRas-related GTP-binding protein C. (401 aa)
L5JMV1_PTEALRas-related GTP-binding protein D. (420 aa)
L5JMI5_PTEALSestrin-1. (608 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (183 aa)
RPS19Doublesex-and mab-3-related transcription factor C2. (525 aa)
L5L6E4_PTEALUncharacterized protein. (1426 aa)
KPTNKaptin. (435 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (506 aa)
L5L5I6_PTEALDEP domain-containing protein 5. (1593 aa)
CASTOR1GATS-like protein 3. (329 aa)
CRYBB3Beta-crystallin B3; Belongs to the beta/gamma-crystallin family. (249 aa)
L5L553_PTEALV-type proton ATPase catalytic subunit A. (574 aa)
L5L4F3_PTEALTankyrase_bdg_C domain-containing protein. (312 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
L5L194_PTEALV-type proton ATPase subunit e 1. (186 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3. (274 aa)
L5KYI0_PTEALV-type proton ATPase subunit E 1. (220 aa)
DMRTA1Doublesex-and mab-3-related transcription factor A1. (501 aa)
WDR59WD repeat-containing protein 59. (968 aa)
GCN1Translational activator GCN1. (2697 aa)
L5KWV4_PTEALDoublesex-and mab-3-related transcription factor C2. (213 aa)
FLCNFolliculin. (582 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
NPRL2Tumor suppressor candidate 4. (380 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
SEH1LNucleoporin SEH1; Belongs to the WD repeat SEC13 family. (427 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
SH3BP4SH3 domain-binding protein 4. (966 aa)
ATP6V1E2V-type proton ATPase subunit E 2. (226 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1122 aa)
BMT2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa)
L5KRW5_PTEALThioredoxin domain-containing protein 11. (821 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
L5KRC6_PTEALV-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (311 aa)
L5KPM1_PTEALV-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (852 aa)
MACC1Metastasis-associated in colon cancer protein 1. (852 aa)
ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
RPTORRegulatory-associated protein of mTOR. (1335 aa)
SZT2Uncharacterized protein. (3430 aa)
L5KLX3_PTEALWD repeat-containing protein mio. (830 aa)
L5KKL8_PTEALPutative sodium-coupled neutral amino acid transporter 9. (412 aa)
NPRL3Uncharacterized protein. (570 aa)
CNSTConsortin_C domain-containing protein. (731 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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