STRINGSTRING
ATG2B ATG2B BECN1 BECN1 GABARAP GABARAP PPP2CB PPP2CB ATG7 ATG7 MTOR MTOR ATG10 ATG10 RPTOR RPTOR WIPI1 WIPI1 ATG2A ATG2A ULK2 ULK2 GABARAPL2 GABARAPL2 PIK3R4 PIK3R4 ATG9A ATG9A ATG16L1 ATG16L1 GABARAPL1 GABARAPL1 ATG4D ATG4D ATG101 ATG101
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG2BAutophagy-related protein 2 like protein B. (2078 aa)
BECN1Beclin-1. (470 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (743 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2208 aa)
ATG10Autophagy-related protein 10. (242 aa)
RPTORRegulatory-associated protein of mTOR. (1335 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1. (437 aa)
ATG2AAutophagy-related protein 2 like protein A. (998 aa)
ULK2Serine/threonine-protein kinase ULK2. (1641 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1380 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (810 aa)
ATG16L1Autophagy-related protein 16-1. (608 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (442 aa)
ATG101Autophagy-related protein 101. (218 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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