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MAP1LC3B MAP1LC3B L5JMB5_PTEAL L5JMB5_PTEAL GCLC GCLC ALOX15 ALOX15 SAT2 SAT2 GSS GSS MAP1LC3A MAP1LC3A TP53 TP53 SLC40A1 SLC40A1 PRNP PRNP ACSL5 ACSL5 STEAP3 STEAP3 GCLM GCLM SLC39A8 SLC39A8 L5K9G6_PTEAL L5K9G6_PTEAL L5K9G9_PTEAL L5K9G9_PTEAL L5K9N8_PTEAL L5K9N8_PTEAL ATG7 ATG7 VDAC3 VDAC3 ACSL1 ACSL1 LPCAT3 LPCAT3 VDAC2 VDAC2 FTMT FTMT SAT1 SAT1 SLC3A2 SLC3A2 FTH1 FTH1 PCBP1 PCBP1 L5KZ19_PTEAL L5KZ19_PTEAL L5KZX6_PTEAL L5KZX6_PTEAL SLC7A11 SLC7A11 FTL FTL SLC39A14 SLC39A14 SLC11A2 SLC11A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP1LC3BMicrotubule-associated proteins 1A/1B light chain 3B. (125 aa)
L5JMB5_PTEALCeruloplasmin; Belongs to the multicopper oxidase family. (1089 aa)
GCLCGlutamate--cysteine ligase catalytic subunit. (637 aa)
ALOX15Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
SAT2Diamine acetyltransferase 2. (170 aa)
GSSGlutathione synthetase. (544 aa)
MAP1LC3AMicrotubule-associated proteins 1A/1B light chain 3A. (121 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (378 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (543 aa)
PRNPMajor prion protein; Belongs to the prion family. (264 aa)
ACSL5Long-chain-fatty-acid--CoA ligase 5. (734 aa)
STEAP3Metalloreductase STEAP3. (518 aa)
GCLMGlutamate--cysteine ligase regulatory subunit. (274 aa)
SLC39A8Zinc transporter ZIP8. (485 aa)
L5K9G6_PTEALCytochrome b-245 heavy chain. (529 aa)
L5K9G9_PTEALFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (185 aa)
L5K9N8_PTEALLong-chain-fatty-acid--CoA ligase 4. (553 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (743 aa)
VDAC3Voltage-dependent anion-selective channel protein 3. (372 aa)
ACSL1Long-chain-fatty-acid--CoA ligase 1. (687 aa)
LPCAT3Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (486 aa)
VDAC2Voltage-dependent anion-selective channel protein 2. (283 aa)
FTMTFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (241 aa)
SAT1Diamine acetyltransferase 1. (171 aa)
SLC3A24F2 cell-surface antigen heavy chain. (526 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (164 aa)
PCBP1Poly(RC)-binding protein 1. (356 aa)
L5KZ19_PTEALSerotransferrin; Belongs to the transferrin family. (707 aa)
L5KZX6_PTEALInhibitor of carbonic anhydrase; Belongs to the transferrin family. (636 aa)
SLC7A11Cystine/glutamate transporter. (688 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
SLC39A14Zinc transporter ZIP14. (521 aa)
SLC11A2Natural resistance-associated macrophage protein 2. (617 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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