STRINGSTRING
WNT11 WNT11 FZD4 FZD4 DVL3 DVL3 INHBA INHBA SOX2 SOX2 FZD1 FZD1 ID3 ID3 HOXB1 HOXB1 AKT1 AKT1 L5JT49_PTEAL L5JT49_PTEAL WNT5B WNT5B PCGF2 PCGF2 MYF5 MYF5 WNT4 WNT4 ZIC3 ZIC3 SMAD5 SMAD5 IGF1R IGF1R FGFR4 FGFR4 ID1 ID1 REST REST WNT9A WNT9A RIF1 RIF1 HOXD1 HOXD1 BMPR2 BMPR2 FZD7 FZD7 DVL2 DVL2 ACVR1C ACVR1C BMP4 BMP4 PCGF6 PCGF6 SMAD3 SMAD3 MAP2K1 MAP2K1 ACVR2A ACVR2A SMAD4 SMAD4 INHBB INHBB ACVR1 ACVR1 FZD5 FZD5 NRAS NRAS LIFR LIFR WNT2B WNT2B ONECUT1 ONECUT1 MYC MYC FZD9 FZD9 L5K6I9_PTEAL L5K6I9_PTEAL JAK1 JAK1 WNT7A WNT7A WNT7B WNT7B FGF2 FGF2 HESX1 HESX1 RAF1 RAF1 WNT1 WNT1 WNT10B WNT10B WNT5A WNT5A BMPR1A BMPR1A NODAL NODAL FZD6 FZD6 SMAD9 SMAD9 IGF1 IGF1 NANOG NANOG DUSP9 DUSP9 AXIN1 AXIN1 MAPK3 MAPK3 AKT3 AKT3 ISL1 ISL1 GRB2 GRB2 APC APC PIK3R1 PIK3R1 IL6ST IL6ST DLX5 DLX5 AXIN2 AXIN2 HRAS HRAS HOXA1 HOXA1 PIK3CA PIK3CA ACVR2B ACVR2B SMARCAD1 SMARCAD1 ID2 ID2 FZD10 FZD10 WNT3 WNT3 WNT2 WNT2 FZD2 FZD2 MEIS1 MEIS1 OTX1 OTX1 INHBE INHBE LHX5 LHX5 INHBC INHBC TBX3 TBX3 MAPK13 MAPK13 BMI1 BMI1 WNT10A WNT10A SMAD1 SMAD1 HAND1 HAND1 WNT6 WNT6 FZD3 FZD3 PCGF1 PCGF1 ACVR1B ACVR1B LIF LIF KLF4 KLF4 JAK3 JAK3 PIK3R2 PIK3R2 DVL1 DVL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (479 aa)
DVL3Segment polarity protein dishevelled like protein DVL-3. (288 aa)
INHBAInhibin beta A chain. (423 aa)
SOX2Transcription factor SOX-2. (273 aa)
FZD1Frizzled-1. (190 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
HOXB1Homeobox protein Hox-B1. (304 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
L5JT49_PTEALProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (218 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
PCGF2Polycomb group RING finger protein 2. (173 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
ZIC3Zinc finger protein ZIC 3. (469 aa)
SMAD5Mothers against decapentaplegic homolog. (462 aa)
IGF1RInsulin-like growth factor 1 receptor. (862 aa)
FGFR4Fibroblast growth factor receptor. (820 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
RESTRE1-silencing transcription factor. (967 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (299 aa)
RIF1Telomere-associated protein RIF1. (2453 aa)
HOXD1Homeobox protein Hox-D1. (320 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1039 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
DVL2Segment polarity protein dishevelled like protein DVL-2. (733 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
PCGF6Cytosolic purine 5'-nucleotidase. (897 aa)
SMAD3Mothers against decapentaplegic homolog. (460 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (495 aa)
SMAD4Mothers against decapentaplegic homolog. (549 aa)
INHBBInhibin beta B chain. (320 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (493 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (564 aa)
NRASGTPase NRas. (189 aa)
LIFRLeukemia inhibitory factor receptor. (1095 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
ONECUT1One cut domain family member. (464 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (440 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (546 aa)
L5K6I9_PTEALPhosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
JAK1Tyrosine-protein kinase. (1170 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (174 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (134 aa)
HESX1Homeobox expressed in ES cell 1. (185 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (642 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (661 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
NODALNodal like protein. (347 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (682 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
IGF1Insulin-like growth factor I. (280 aa)
NANOGHomeobox protein NANOGP8. (295 aa)
DUSP9Dual specificity protein phosphatase 9. (401 aa)
AXIN1Axin-1. (867 aa)
MAPK3Mitogen-activated protein kinase 3; Belongs to the protein kinase superfamily. (410 aa)
AKT3Non-specific serine/threonine protein kinase. (283 aa)
ISL1Insulin protein enhancer protein ISL-1. (383 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
APCUncharacterized protein. (2861 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (165 aa)
IL6STInterleukin-6 receptor subunit beta. (924 aa)
DLX5Homeobox protein DLX-5. (289 aa)
AXIN2Axin-2. (783 aa)
HRASGTPase HRas. (187 aa)
HOXA1Homeobox protein Hox-A1. (333 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (496 aa)
SMARCAD1annotation not available (1057 aa)
ID2DNA-binding protein inhibitor ID-2. (184 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (509 aa)
MEIS1Homeobox protein Meis2. (475 aa)
OTX1Homeobox protein OTX1. (355 aa)
INHBEInhibin beta E chain. (351 aa)
LHX5LIM/homeobox protein Lhx5. (402 aa)
INHBCInhibin beta C chain. (351 aa)
TBX3T-box transcription factor TBX3. (746 aa)
MAPK13Mitogen-activated protein kinase. (353 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
HAND1Heart-and neural crest derivatives-expressed protein 1. (253 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (148 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PCGF1Polycomb group RING finger protein 1. (272 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
LIFLeukemia inhibitory factor. (204 aa)
KLF4Krueppel-like factor 2. (129 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (710 aa)
DVL1Segment polarity protein dishevelled like protein DVL-1. (699 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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