STRINGSTRING
HTR1B HTR1B HTR1E HTR1E GNGT2 GNGT2 HTR7 HTR7 CACNA1C CACNA1C HTR1D HTR1D HTR6 HTR6 KCNJ9 KCNJ9 GABRB1 GABRB1 ALOX15 ALOX15 ALOX12B ALOX12B L5JYM5_PTEAL L5JYM5_PTEAL ALOX12 ALOX12 L5JZ46_PTEAL L5JZ46_PTEAL KCNJ3 KCNJ3 PLCB1 PLCB1 MAP2K1 MAP2K1 PLA2G4F PLA2G4F GNAI3 GNAI3 NRAS NRAS GNG2 GNG2 L5K4C8_PTEAL L5K4C8_PTEAL CACNA1A CACNA1A GNG12 GNG12 L5K6T8_PTEAL L5K6T8_PTEAL PRKACB PRKACB GNG5 GNG5 TRPC1 TRPC1 GNG14 GNG14 PRKACA PRKACA RAF1 RAF1 L5K9D4_PTEAL L5K9D4_PTEAL PTGS1 PTGS1 KCNJ6 KCNJ6 CASP3 CASP3 HTR2A HTR2A HTR2C HTR2C KCNJ5 KCNJ5 GNB3 GNB3 GNG13 GNG13 MAPK3 MAPK3 KCNN2 KCNN2 ITPR2 ITPR2 PRKCB PRKCB HTR3A HTR3A GNGT1 GNGT1 HRAS HRAS GNG11 GNG11 GNG8 GNG8 PLCB3 PLCB3 GNG3 GNG3 KCND2 KCND2 GNB4 GNB4 GNAI2 GNAI2 GNAO1 GNAO1 PTGS2 PTGS2 APP APP ITPR3 ITPR3 PLA2G4A PLA2G4A GABRB3 GABRB3 PRKCG PRKCG HTR4 HTR4 DUSP1 DUSP1 GNG7 GNG7 TPH1 TPH1 HTR5A HTR5A GNB1 GNB1 GNB2 GNB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
HTR75-hydroxytryptamine receptor 7. (435 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2001 aa)
HTR1D5-hydroxytryptamine receptor 1D. (400 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (438 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (393 aa)
GABRB1Gamma-aminobutyric acid receptor subunit beta-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (319 aa)
ALOX15Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (709 aa)
L5JYM5_PTEAL5-hydroxytryptamine receptor 5B. (370 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
L5JZ46_PTEALGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (614 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1. (322 aa)
PLCB11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1. (130 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLA2G4FPhospholipase A2. (842 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
NRASGTPase NRas. (189 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
L5K4C8_PTEALCytochrome P450 2J2; Belongs to the cytochrome P450 family. (498 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (108 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
L5K6T8_PTEALGuanine nucleotide-binding protein G(Q) subunit alpha. (235 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (336 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (120 aa)
TRPC1Short transient receptor potential channel 1; Belongs to the transient receptor (TC 1.A.4) family. (758 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (346 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (642 aa)
L5K9D4_PTEALCytochrome P450 2D15. (137 aa)
PTGS1Prostaglandin G/H synthase 1. (523 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (465 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
HTR2A5-hydroxytryptamine receptor 2A. (438 aa)
HTR2C5-hydroxytryptamine receptor 2C; Belongs to the G-protein coupled receptor 1 family. (348 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (419 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
MAPK3Mitogen-activated protein kinase 3; Belongs to the protein kinase superfamily. (410 aa)
KCNN2Small conductance calcium-activated potassium channel protein 2. (447 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (3308 aa)
PRKCBProtein kinase C beta type. (374 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
HRASGTPase HRas. (187 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1229 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (372 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
GNAI2Guanine nucleotide-binding protein G(I), alpha-2 subunit. (157 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (111 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
APPAmyloid beta A4 protein. (748 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa)
PLA2G4APhospholipase A2. (737 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (386 aa)
PRKCGNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (448 aa)
DUSP1Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (225 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
TPH1Tryptophan 5-hydroxylase 1. (444 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (383 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (105 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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