STRINGSTRING
PPP2R5C PPP2R5C ARRB1 ARRB1 GNGT2 GNGT2 FOS FOS AKT1 AKT1 CACNA1C CACNA1C KCNJ9 KCNJ9 ARRB2 ARRB2 PPP2R2B PPP2R2B MAPK9 MAPK9 L5JZ46_PTEAL L5JZ46_PTEAL KCNJ3 KCNJ3 PLCB1 PLCB1 CREB1 CREB1 SCN1A SCN1A GNAI3 GNAI3 ATF2 ATF2 GNG2 GNG2 PPP3CA PPP3CA CACNA1A CACNA1A L5K5Z5_PTEAL L5K5Z5_PTEAL GNG12 GNG12 L5K6T8_PTEAL L5K6T8_PTEAL PRKACB PRKACB GNG5 GNG5 CAMK2D CAMK2D PPP2R2C PPP2R2C GNG14 GNG14 PRKACA PRKACA PPP2CB PPP2CB PPP2R3B PPP2R3B KCNJ6 KCNJ6 ATF4 ATF4 PPP2R5E PPP2R5E CREB3 CREB3 KIF5B KIF5B KCNJ5 KCNJ5 PPP3CB PPP3CB GNB3 GNB3 GNG13 GNG13 AKT3 AKT3 CALY CALY DRD2 DRD2 ITPR2 ITPR2 PRKCB PRKCB GRIN2B GRIN2B PPP2R3C PPP2R3C CALM2 CALM2 PPP2R1B PPP2R1B GNGT1 GNGT1 CREB5 CREB5 PPP2R5B PPP2R5B GRIN2A GRIN2A GNG11 GNG11 GNG8 GNG8 CREB3L2 CREB3L2 PPP1CA PPP1CA PLCB3 PLCB3 GNG3 GNG3 GNB4 GNB4 PPP1CB PPP1CB GNAL GNAL GNAI2 GNAI2 GNAO1 GNAO1 KIF5A KIF5A CREB3L1 CREB3L1 MAPK10 MAPK10 PPP2R5A PPP2R5A MAPK13 MAPK13 ITPR3 ITPR3 PPP2R3A PPP2R3A GRIA4 GRIA4 PRKCG PRKCG CAMK2A CAMK2A GRIA1 GRIA1 DRD1 DRD1 PPP2R1A PPP2R1A ATF6B ATF6B GNG7 GNG7 CALML6 CALML6 GSK3A GSK3A GNB1 GNB1 PPP3CC PPP3CC GNB2 GNB2 CREB3L3 CREB3L3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
ARRB1Beta-arrestin-1. (413 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
FOSProto-oncogene protein c-fos. (380 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2001 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (393 aa)
ARRB2Beta-arrestin-2. (409 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa)
MAPK9Mitogen-activated protein kinase 9. (209 aa)
L5JZ46_PTEALGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (614 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1. (322 aa)
PLCB11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1. (130 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (341 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (505 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PPP3CASerine/threonine-protein phosphatase. (508 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha-1A. (108 aa)
L5K5Z5_PTEALTransmembrane O-methyltransferase. (258 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
L5K6T8_PTEALGuanine nucleotide-binding protein G(Q) subunit alpha. (235 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (336 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (120 aa)
CAMK2DUncharacterized protein. (111 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (358 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (346 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (578 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (465 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (376 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (419 aa)
PPP3CBSerine/threonine-protein phosphatase. (507 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
AKT3Non-specific serine/threonine protein kinase. (283 aa)
CALYNeuron-specific vesicular protein calcyon. (93 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (327 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (3308 aa)
PRKCBProtein kinase C beta type. (374 aa)
GRIN2BGlutamate [NMDA] receptor subunit epsilon-2. (1355 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (453 aa)
CALM2Calmodulin; Belongs to the calmodulin family. (166 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (992 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (483 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
GRIN2AGlutamate [NMDA] receptor subunit epsilon-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1118 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1229 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha. (380 aa)
GNAI2Guanine nucleotide-binding protein G(I), alpha-2 subunit. (157 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (111 aa)
KIF5AKinesin heavy chain isoform 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
MAPK10Mitogen-activated protein kinase 10. (146 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
MAPK13Mitogen-activated protein kinase. (353 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha. (1111 aa)
GRIA4Glutamate receptor 4. (826 aa)
PRKCGNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II alpha chain; Belongs to the protein kinase superfamily. (489 aa)
GRIA1Glutamate receptor 1. (827 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (445 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (2470 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (698 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CALML6Calmodulin-like protein 6. (138 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (415 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (383 aa)
PPP3CCSerine/threonine-protein phosphatase. (640 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (105 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (446 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.