STRINGSTRING
ARG1 ARG1 LAMA4 LAMA4 LAMB1 LAMB1 COL1A1 COL1A1 NOS2 NOS2 CD14 CD14 CSF2 CSF2 RAB7B RAB7B ITGB2 ITGB2 IL10 IL10 L5JZ46_PTEAL L5JZ46_PTEAL PLCB1 PLCB1 COL3A1 COL3A1 IL1R2 IL1R2 LAMA3 LAMA3 L5K361_PTEAL L5K361_PTEAL IL1R1 IL1R1 L5K5N2_PTEAL L5K5N2_PTEAL GNA14 GNA14 PRDX1 PRDX1 L5K6I9_PTEAL L5K6I9_PTEAL C8B C8B C8G C8G L5K6T8_PTEAL L5K6T8_PTEAL PRKACB PRKACB NFKB1 NFKB1 HSPB1 HSPB1 PRKACA PRKACA CXCL8 CXCL8 TGFB2 TGFB2 CASP3 CASP3 ACTN1 ACTN1 COL4A6 COL4A6 COL4A5 COL4A5 L5KIE8_PTEAL L5KIE8_PTEAL SERPINB10 SERPINB10 ITGAM ITGAM L5KKA2_PTEAL L5KKA2_PTEAL PRKCB PRKCB PIK3R1 PIK3R1 L5KLX5_PTEAL L5KLX5_PTEAL PTK2 PTK2 ADCY1 ADCY1 MUC2 MUC2 RELA RELA COL1A2 COL1A2 PIK3CA PIK3CA IL6 IL6 ACTN4 ACTN4 PLCB3 PLCB3 TGFB1 TGFB1 IL1B IL1B GNAL GNAL COL4A1 COL4A1 RAB5B RAB5B COL4A2 COL4A2 RAB7A RAB7A LAMC2 LAMC2 RAB5A RAB5A LAMC1 LAMC1 L5L099_PTEAL L5L099_PTEAL PRKCG PRKCG L5L0V2_PTEAL L5L0V2_PTEAL FN1 FN1 IL12B IL12B TNF TNF GNA15 GNA15 L5L777_PTEAL L5L777_PTEAL PIK3R2 PIK3R2 GNA11 GNA11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARG1Arginase. (304 aa)
LAMA4Laminin subunit alpha-4. (1824 aa)
LAMB1Laminin subunit beta-1. (1785 aa)
COL1A1Collagen alpha-1(I) chain. (1459 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1124 aa)
CD14Monocyte differentiation antigen CD14. (365 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
RAB7BRas-related protein Rab-7b. (236 aa)
ITGB2Integrin beta. (778 aa)
IL10Interleukin-10. (178 aa)
L5JZ46_PTEALGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (614 aa)
PLCB11-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1. (130 aa)
COL3A1Collagen alpha-1(III) chain. (1248 aa)
IL1R2Interleukin-1 receptor type II. (439 aa)
LAMA3Laminin subunit alpha-3. (3522 aa)
L5K361_PTEALT-cell surface glycoprotein CD1b-1. (441 aa)
IL1R1Interleukin-1 receptor type I. (569 aa)
L5K5N2_PTEALT-cell surface glycoprotein CD1a. (363 aa)
GNA14Guanine nucleotide-binding protein subunit alpha-14. (253 aa)
PRDX1Peroxiredoxin-1. (227 aa)
L5K6I9_PTEALPhosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
C8BComplement component C8 beta chain. (631 aa)
C8GComplement component C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (229 aa)
L5K6T8_PTEALGuanine nucleotide-binding protein G(Q) subunit alpha. (235 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (336 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (933 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (346 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
ACTN1Alpha-actinin-1. (914 aa)
COL4A6Collagen alpha-6(IV) chain. (206 aa)
COL4A5Collagen alpha-1(IV) chain. (1464 aa)
L5KIE8_PTEALSerpin B13; Belongs to the serpin family. (277 aa)
SERPINB10Serpin B10; Belongs to the serpin family. (777 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1263 aa)
L5KKA2_PTEALT-cell surface glycoprotein CD1b. (362 aa)
PRKCBProtein kinase C beta type. (374 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (165 aa)
L5KLX5_PTEALT-cell surface glycoprotein CD1e, membrane-associated. (300 aa)
PTK2Focal adhesion kinase 1. (387 aa)
ADCY1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (298 aa)
MUC2Mucin-2. (4969 aa)
RELATranscription factor p65. (533 aa)
COL1A2Collagen alpha-2(I) chain. (1369 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
IL6Interleukin-6. (202 aa)
ACTN4Alpha-actinin-4. (911 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1229 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha. (380 aa)
COL4A1Collagen alpha-1(IV) chain. (1521 aa)
RAB5BRas-related protein Rab-5B. (256 aa)
COL4A2Collagen alpha-2(IV) chain. (169 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
LAMC2Laminin subunit gamma-2. (1229 aa)
RAB5ARas-related protein Rab-5A. (215 aa)
LAMC1Laminin subunit gamma-1. (1476 aa)
L5L099_PTEALC-X-C motif chemokine. (130 aa)
PRKCGNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
L5L0V2_PTEALCathepsin G; Belongs to the peptidase S1 family. (237 aa)
FN1Fibronectin. (2477 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (313 aa)
L5L777_PTEALIg heavy chain V-I region V35. (120 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (710 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (301 aa)
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.