STRINGSTRING
CFR80_01630 CFR80_01630 metXA metXA ggt-2 ggt-2 GCA_000227565_03485 GCA_000227565_03485 CFR80_04635 CFR80_04635 CFR80_04685 CFR80_04685 cysC cysC CFR80_04700 CFR80_04700 bioD bioD CFR80_04885 CFR80_04885 CFR80_04890 CFR80_04890 mtnK mtnK ackA ackA metK metK accD accD folD-3 folD-3 accA accA CFR80_00975 CFR80_00975 gshB gshB mtnP mtnP CFR80_00475 CFR80_00475 mtnA mtnA CFR80_07510 CFR80_07510 GCA_000227565_02846 GCA_000227565_02846 thiC thiC metH metH lipA lipA CFR80_08475 CFR80_08475 pdhA pdhA GCA_000227565_02654 GCA_000227565_02654 thiM thiM thiL thiL folD-2 folD-2 folD folD CFR80_06070 CFR80_06070 thiS thiS thiG thiG CFR80_06605 CFR80_06605 bioB bioB CFR80_06390 CFR80_06390 asd asd accC accC cysK cysK mtnC mtnC mtnD mtnD mtnB mtnB ggt ggt CFR80_11140 CFR80_11140 cysE cysE thiD thiD tenA tenA CFR80_11635 CFR80_11635 GCA_000227565_01669 GCA_000227565_01669 CFR80_18250 CFR80_18250 GCA_000227565_01508 GCA_000227565_01508 CFR80_05660 CFR80_05660 GCA_000227565_01289 GCA_000227565_01289 CFR80_13625 CFR80_13625 CFR80_11485 CFR80_11485 thiE thiE CFR80_13590 CFR80_13590 GCA_000227565_00817 GCA_000227565_00817 CFR80_12840 CFR80_12840 CFR80_16215 CFR80_16215 GCA_000227565_00482 GCA_000227565_00482 metE metE GCA_000227565_00595 GCA_000227565_00595 CFR80_10745 CFR80_10745 CFR80_13795 CFR80_13795
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CFR80_01630Unannotated protein. (530 aa)
metXAUnannotated protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (389 aa)
ggt-2Unannotated protein. (591 aa)
GCA_000227565_03485Unannotated protein. (217 aa)
CFR80_04635Unannotated protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (284 aa)
CFR80_04685Unannotated protein. (562 aa)
cysCUnannotated protein; Catalyzes the synthesis of activated sulfate. (628 aa)
CFR80_04700Unannotated protein. (264 aa)
bioDUnannotated protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (469 aa)
CFR80_04885Unannotated protein. (394 aa)
CFR80_04890Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
mtnKUnannotated protein; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (411 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
metKUnannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
folD-3Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (309 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (341 aa)
CFR80_00975Unannotated protein. (316 aa)
gshBUnannotated protein; Belongs to the prokaryotic GSH synthase family. (336 aa)
mtnPUnannotated protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (301 aa)
CFR80_00475Unannotated protein. (486 aa)
mtnAUnannotated protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (388 aa)
CFR80_07510Unannotated protein. (640 aa)
GCA_000227565_02846Unannotated protein. (410 aa)
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (613 aa)
metHUnannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1169 aa)
lipAUnannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (330 aa)
CFR80_08475Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (452 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (222 aa)
GCA_000227565_02654Unannotated protein. (120 aa)
thiMUnannotated protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (277 aa)
thiLUnannotated protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (330 aa)
folD-2Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
folDUnannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (304 aa)
CFR80_06070Unannotated protein. (242 aa)
thiSUnannotated protein. (66 aa)
thiGUnannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa)
CFR80_06605Unannotated protein. (206 aa)
bioBUnannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (339 aa)
CFR80_06390Unannotated protein. (400 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa)
accCUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
cysKUnannotated protein. (329 aa)
mtnCUnannotated protein; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (238 aa)
mtnDUnannotated protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (180 aa)
mtnBUnannotated protein; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (207 aa)
ggtUnannotated protein. (556 aa)
CFR80_11140Unannotated protein. (290 aa)
cysEUnannotated protein. (287 aa)
thiDUnannotated protein. (267 aa)
tenAUnannotated protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (236 aa)
CFR80_11635Unannotated protein. (497 aa)
GCA_000227565_01669Unannotated protein. (321 aa)
CFR80_18250Unannotated protein. (650 aa)
GCA_000227565_01508Unannotated protein. (341 aa)
CFR80_05660Unannotated protein. (340 aa)
GCA_000227565_01289Unannotated protein. (341 aa)
CFR80_13625Unannotated protein. (590 aa)
CFR80_11485Unannotated protein. (445 aa)
thiEUnannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa)
CFR80_13590Unannotated protein. (312 aa)
GCA_000227565_00817Unannotated protein. (242 aa)
CFR80_12840Unannotated protein. (446 aa)
CFR80_16215Unannotated protein. (132 aa)
GCA_000227565_00482Unannotated protein. (442 aa)
metEUnannotated protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (764 aa)
GCA_000227565_00595Unannotated protein. (311 aa)
CFR80_10745Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
CFR80_13795Unannotated protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (360 aa)
Your Current Organism:
Komagataeibacter oboediens
NCBI taxonomy Id: 940286
Other names: Gluconacetobacter oboediens 174Bp2, K. oboediens 174Bp2, Komagataeibacter oboediens 174Bp2, Komagataeibacter oboediens str. 174Bp2, Komagataeibacter oboediens strain 174Bp2
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