STRINGSTRING
EYM_00420 EYM_00420 EYM_01110 EYM_01110 EYM_01235 EYM_01235 EYM_02405 EYM_02405 EYM_02660 EYM_02660 EYM_02665 EYM_02665 EYM_02780 EYM_02780 EYM_03080 EYM_03080 EYM_03975 EYM_03975 EYM_04015 EYM_04015 EYM_04020 EYM_04020 EYM_04025 EYM_04025 EYM_04030 EYM_04030 EYM_04610 EYM_04610 EYM_04795 EYM_04795 EYM_04800 EYM_04800 EYM_04805 EYM_04805 EYM_05010 EYM_05010 EYM_05135 EYM_05135 mtnP mtnP thi4 thi4 thiC thiC EYM_06300 EYM_06300 EYM_06430 EYM_06430 EYM_06810 EYM_06810 acsA acsA EYM_07195 EYM_07195 EYM_07325 EYM_07325 EYM_07615 EYM_07615 metE metE EYM_07800 EYM_07800
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EYM_00420Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
EYM_01110Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
EYM_01235Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (286 aa)
EYM_02405Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (360 aa)
EYM_02660Indolepyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
EYM_02665Indolepyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (642 aa)
EYM_02780Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (257 aa)
EYM_03080Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (217 aa)
EYM_03975Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
EYM_04015Pyruvate ferredoxin oxidoreductase subunit beta; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
EYM_04020Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
EYM_04025Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
EYM_04030Pyruvate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
EYM_04610Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (645 aa)
EYM_047952-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
EYM_048002-oxoglutarate ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
EYM_048052-oxoglutarate ferredoxin oxidoreductase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
EYM_05010Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (197 aa)
EYM_05135Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (384 aa)
mtnP5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (274 aa)
thi4Ribulose-1,5-biphosphate synthetase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (266 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (443 aa)
EYM_06300Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (400 aa)
EYM_06430Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
EYM_06810Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
acsA3-hydroxypropionyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa)
EYM_07195Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (333 aa)
EYM_07325Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
EYM_07615Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (656 aa)
metEmethylcobamide:CoM methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. (350 aa)
EYM_07800Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (438 aa)
Your Current Organism:
Ignicoccus islandicus
NCBI taxonomy Id: 940295
Other names: I. islandicus DSM 13165, Ignicoccus islandicus DSM 13165, Ignicoccus islandicus Ko18, Ignicoccus islandicus str. DSM 13165, Ignicoccus islandicus strain DSM 13165
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