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sucC sucC sucD sucD EYM_01330 EYM_01330 EYM_03995 EYM_03995 EYM_04015 EYM_04015 EYM_04020 EYM_04020 EYM_04025 EYM_04025 EYM_04030 EYM_04030 EYM_04445 EYM_04445 EYM_04795 EYM_04795 EYM_04800 EYM_04800 EYM_04805 EYM_04805 EYM_04810 EYM_04810 EYM_04935 EYM_04935 sdhA sdhA EYM_06970 EYM_06970 EYM_07790 EYM_07790
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (377 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
EYM_01330Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (262 aa)
EYM_03995Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (310 aa)
EYM_04015Pyruvate ferredoxin oxidoreductase subunit beta; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
EYM_04020Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
EYM_04025Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
EYM_04030Pyruvate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
EYM_04445Histone-lysine N-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
EYM_047952-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
EYM_048002-oxoglutarate ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
EYM_048052-oxoglutarate ferredoxin oxidoreductase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
EYM_048104Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa)
EYM_04935Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
EYM_06970Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
EYM_07790Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (496 aa)
Your Current Organism:
Ignicoccus islandicus
NCBI taxonomy Id: 940295
Other names: I. islandicus DSM 13165, Ignicoccus islandicus DSM 13165, Ignicoccus islandicus Ko18, Ignicoccus islandicus str. DSM 13165, Ignicoccus islandicus strain DSM 13165
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