STRINGSTRING
argG argG aroK aroK gltX gltX EYM_00310 EYM_00310 EYM_00420 EYM_00420 EYM_00425 EYM_00425 EYM_00440 EYM_00440 sucC sucC sucD sucD adkA adkA EYM_00560 EYM_00560 trpB trpB EYM_00605 EYM_00605 leuD leuD fbp fbp EYM_00915 EYM_00915 EYM_00940 EYM_00940 EYM_01025 EYM_01025 EYM_01085 EYM_01085 EYM_01110 EYM_01110 EYM_01160 EYM_01160 EYM_01165 EYM_01165 EYM_01320 EYM_01320 EYM_01330 EYM_01330 EYM_01345 EYM_01345 EYM_01350 EYM_01350 EYM_01640 EYM_01640 hisF hisF EYM_01835 EYM_01835 EYM_01845 EYM_01845 lysJ lysJ purT purT ilvD ilvD aroE aroE lysY lysY EYM_02490 EYM_02490 purF purF EYM_02600 EYM_02600 purL purL pgk pgk EYM_02770 EYM_02770 fni fni thrB thrB ribH ribH hisD hisD hisA hisA EYM_03345 EYM_03345 purE purE EYM_03450 EYM_03450 EYM_03500 EYM_03500 EYM_03510 EYM_03510 EYM_03550 EYM_03550 EYM_03590 EYM_03590 EYM_03675 EYM_03675 EYM_03730 EYM_03730 leuC leuC trpF trpF leuC-2 leuC-2 gap gap EYM_03975 EYM_03975 EYM_03995 EYM_03995 EYM_04015 EYM_04015 EYM_04020 EYM_04020 EYM_04025 EYM_04025 EYM_04030 EYM_04030 EYM_04105 EYM_04105 EYM_04165 EYM_04165 EYM_04230 EYM_04230 purS purS purC purC EYM_04310 EYM_04310 EYM_04320 EYM_04320 EYM_04345 EYM_04345 EYM_04415 EYM_04415 EYM_04445 EYM_04445 eno eno panB panB aroA aroA hemA hemA ilvC ilvC EYM_04740 EYM_04740 EYM_04745 EYM_04745 EYM_04795 EYM_04795 EYM_04800 EYM_04800 EYM_04805 EYM_04805 EYM_04810 EYM_04810 EYM_04880 EYM_04880 EYM_04935 EYM_04935 sdhA sdhA EYM_05455 EYM_05455 hisB hisB EYM_05470 EYM_05470 leuD-2 leuD-2 EYM_05700 EYM_05700 EYM_05750 EYM_05750 aroC aroC EYM_05815 EYM_05815 EYM_05830 EYM_05830 EYM_05865 EYM_05865 mqnD mqnD EYM_06065 EYM_06065 glyA glyA lysZ lysZ proC proC EYM_06245 EYM_06245 EYM_06325 EYM_06325 EYM_06375 EYM_06375 EYM_06380 EYM_06380 EYM_06425 EYM_06425 EYM_06430 EYM_06430 EYM_06775 EYM_06775 EYM_06895 EYM_06895 EYM_06900 EYM_06900 acsA acsA EYM_06950 EYM_06950 EYM_06970 EYM_06970 hisE hisE hisH hisH EYM_07050 EYM_07050 prs prs trpA trpA apgM apgM hemC hemC hemL hemL EYM_07310 EYM_07310 EYM_07320 EYM_07320 EYM_07325 EYM_07325 EYM_07385 EYM_07385 hisG hisG mvk mvk EYM_07420 EYM_07420 EYM_07440 EYM_07440 EYM_07460 EYM_07460 tpiA tpiA EYM_07630 EYM_07630 EYM_07655 EYM_07655 metE metE ndk ndk EYM_07790 EYM_07790 trpD trpD purP purP EYM_07935 EYM_07935
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa)
aroKShikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (568 aa)
EYM_00310Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (184 aa)
EYM_00420Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
EYM_00425acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
EYM_00440Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (428 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (377 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
adkAAdenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal adenylate kinase family. (199 aa)
EYM_00560dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (188 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (426 aa)
EYM_006053-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family. (416 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (168 aa)
fbpFructose-1 6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (391 aa)
EYM_00915Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (377 aa)
EYM_009403-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
EYM_010255-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Similar to PurP from Methanocaldococcus jannaschii; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
EYM_01085Phosphoglucomutase; Catalyzes the interconversion of alpha-D-mannose 1-phosphate to alpha-D-mannose 6-phosphate and alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphohexose mutase family. (457 aa)
EYM_01110Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
EYM_01160Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
EYM_01165Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
EYM_013203-dehydroquinate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
EYM_01330Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (262 aa)
EYM_01345Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. UPF0219 family. (352 aa)
EYM_01350Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (355 aa)
EYM_01640Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (426 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
EYM_01835Alpha-isopropylmalate/homocitrate synthase family transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (548 aa)
EYM_01845Anthranilate synthase subunit II; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
lysJAcetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (385 aa)
purTPhosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (403 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (552 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (270 aa)
lysYN-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (353 aa)
EYM_024903-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (431 aa)
EYM_02600Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (712 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (410 aa)
EYM_02770Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (365 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (312 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (137 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (399 aa)
hisAHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (243 aa)
EYM_03345Glucose-1-phosphate thymidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (139 aa)
EYM_03450Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
EYM_03500Myo-inositol-1-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
EYM_03510Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
EYM_03550Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
EYM_03590Aromatic acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
EYM_036753-dehydroquinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
EYM_03730Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartokinase family. (462 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa)
trpFHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TrpF family. (201 aa)
leuC-23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (429 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
EYM_03975Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
EYM_03995Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (310 aa)
EYM_04015Pyruvate ferredoxin oxidoreductase subunit beta; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
EYM_04020Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
EYM_04025Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
EYM_04030Pyruvate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
EYM_04105Catalyzes the formation of riboflavin and 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine from 6,7-dimethyl-8-(1-D-ribityl)lumazine; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
EYM_04165Hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. (249 aa)
EYM_04230Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
purSHypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the am [...] (97 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (232 aa)
EYM_04310phosphoribosyl-AMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
EYM_04320Histidinol-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
EYM_04345Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (360 aa)
EYM_04415Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (451 aa)
EYM_04445Histone-lysine N-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (243 aa)
aroAHypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (423 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (443 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
EYM_04740Ornithine carbamoyltransferase; Catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (311 aa)
EYM_04745Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (821 aa)
EYM_047952-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
EYM_048002-oxoglutarate ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
EYM_048052-oxoglutarate ferredoxin oxidoreductase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
EYM_048104Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa)
EYM_04880Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (237 aa)
EYM_04935Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
EYM_054552-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
hisBImidazoleglycerol-phosphate dehydratase; Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
EYM_05470Anthranilate synthase subunit I; With component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
leuD-23-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (174 aa)
EYM_05700Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (367 aa)
EYM_05750Coenzyme PQQ biosynthesis protein E; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (391 aa)
EYM_058153,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the formation of 3,4-dihydroxy 2-butanone 4-phosphate from ribulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
EYM_05830Cytidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
EYM_05865dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
mqnDABC transporter substrate-binding protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (271 aa)
EYM_06065Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (268 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (433 aa)
lysZAcetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (264 aa)
proCHypothetical protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (246 aa)
EYM_06245Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (298 aa)
EYM_06325Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (241 aa)
EYM_063752-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (403 aa)
EYM_06380Catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate and the decarboxylation of 3-methylmalate to 2-oxobutyrate and of D-malate to pyruvate; involved in leucine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
EYM_06425Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (348 aa)
EYM_06430Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
EYM_06775Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (444 aa)
EYM_06895Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (341 aa)
EYM_06900Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
acsA3-hydroxypropionyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa)
EYM_06950Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
EYM_06970Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
hisHImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa)
EYM_07050Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (215 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (300 aa)
trpATryptophan synthase subunit alpha; Catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpA family. (246 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (412 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (298 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
EYM_07310Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
EYM_07320Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (100 aa)
EYM_07325Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
EYM_07385Prenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (320 aa)
EYM_07420Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (439 aa)
EYM_07440Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
EYM_07460Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (223 aa)
EYM_07630Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
EYM_07655Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (335 aa)
metEmethylcobamide:CoM methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. (350 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (148 aa)
EYM_07790Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (496 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa)
purP5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (351 aa)
EYM_07935Geranylgeranyl pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (306 aa)
Your Current Organism:
Ignicoccus islandicus
NCBI taxonomy Id: 940295
Other names: I. islandicus DSM 13165, Ignicoccus islandicus DSM 13165, Ignicoccus islandicus Ko18, Ignicoccus islandicus str. DSM 13165, Ignicoccus islandicus strain DSM 13165
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