(21 nodes) Ribonuclease H superfamily network (Shewanella sp. ANA3)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABK46337.1	PFAM: Integrase, catalytic region; KEGG: par:Psyc_0937 putative transposase OrfB. (267 aa)
	ABK46584.1	PFAM: Integrase, catalytic region; KEGG: par:Psyc_0937 putative transposase OrfB. (267 aa)
	orn	Exonuclease, RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (181 aa)
	ABK47215.1	PFAM: 3'-5' exonuclease; KEGG: son:SO1153 exonuclease, putative. (303 aa)
	ABK47485.1	PFAM: Integrase, catalytic region; KEGG: pst:PSPTO2841 ISPsy14, transposase. (513 aa)
	ABK47811.1	PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease. (228 aa)
	ruvC	Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (173 aa)
	ABK48356.1	PFAM: Integrase, catalytic region; KEGG: pfo:Pfl_2131 integrase, catalytic region. (240 aa)
	ABK48480.1	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease. (229 aa)
	ABK48590.1	PFAM: Integrase, catalytic region; KEGG: son:SOA0129 transposase, IS3 family. (167 aa)
	dnaQ	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (242 aa)
	rnhA	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (158 aa)
	ABK50080.1	PFAM: Integrase, catalytic region; KEGG: ppr:PBPRA0979 putative transposase. (617 aa)
	polA	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (922 aa)
	rnd	Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (388 aa)
	rnt	RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (222 aa)
	ABK48799.1	PFAM: Exonuclease, RNase T and DNA polymerase III; Exonuclease C-terminal domain protein; KEGG: son:SO2790 exodeoxyribonuclease I. (470 aa)
	ABK50074.1	KEGG: mlo:mlr6204 hypothetical protein. (480 aa)
	ABK49527.1	PFAM: Integrase, catalytic region; KEGG: pfo:Pfl_2131 integrase, catalytic region. (239 aa)
	ABK48856.1	PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: son:SO1820 DNA polymerase II. (810 aa)
	rnhB	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (209 aa)

Your Current Organism:

Shewanella sp. ANA3

NCBI taxonomy Id: 94122
Other names: S. sp. ANA-3, Shewanella sp. ANA-3, Shewanella sp. arsenana, Shewanella trabarsenatis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK47811.1	ABK48480.1	Shewana3_1577	Shewana3_2251	PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease.	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.	0.925
ABK47811.1	dnaQ	Shewana3_1577	Shewana3_2365	PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.928
ABK47811.1	polA	Shewana3_1577	Shewana3_4109	PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.495
ABK48480.1	ABK47811.1	Shewana3_2251	Shewana3_1577	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.	PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease.	0.925
ABK48480.1	dnaQ	Shewana3_2251	Shewana3_2365	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.930
ABK48480.1	polA	Shewana3_2251	Shewana3_4109	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.508
ABK48480.1	rnhB	Shewana3_2251	Shewana3_2801	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.407
ABK48799.1	rnhA	Shewana3_2572	Shewana3_2366	PFAM: Exonuclease, RNase T and DNA polymerase III; Exonuclease C-terminal domain protein; KEGG: son:SO2790 exodeoxyribonuclease I.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.409
ABK48856.1	polA	Shewana3_2629	Shewana3_4109	PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: son:SO1820 DNA polymerase II.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.956
ABK48856.1	rnhB	Shewana3_2629	Shewana3_2801	PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: son:SO1820 DNA polymerase II.	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.639
dnaQ	ABK47811.1	Shewana3_2365	Shewana3_1577	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease.	0.928
dnaQ	ABK48480.1	Shewana3_2365	Shewana3_2251	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.	0.930
dnaQ	orn	Shewana3_2365	Shewana3_0590	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Exonuclease, RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	0.425
dnaQ	polA	Shewana3_2365	Shewana3_4109	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.495
dnaQ	rnhA	Shewana3_2365	Shewana3_2366	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.959
orn	dnaQ	Shewana3_0590	Shewana3_2365	Exonuclease, RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.425
orn	rnt	Shewana3_0590	Shewana3_2540	Exonuclease, RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.	0.416
polA	ABK47811.1	Shewana3_4109	Shewana3_1577	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: son:SO2855 exonuclease.	0.495
polA	ABK48480.1	Shewana3_4109	Shewana3_2251	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.	0.508
polA	ABK48856.1	Shewana3_4109	Shewana3_2629	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: son:SO1820 DNA polymerase II.	0.956