(39 nodes) Mixed, incl. Protein deneddylation, and Protein neddylation network (Apis cerana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APICC_05370	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (355 aa)
	APICC_05969	S-phase kinase-associated protein. (533 aa)
	APICC_01584	Sentrin-specific protease. (223 aa)
	APICC_01372	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (269 aa)
	APICC_01432	F-box/WD repeat-containing protein. (649 aa)
	APICC_07676	Von Hippel-Lindau disease tumor suppressor. (179 aa)
	APICC_01007	Sterol regulatory element-binding protein cleavage-activating protein. (1333 aa)
	APICC_00834	Peptidylprolyl isomerase. (405 aa)
	APICC_08662	F-box only protein. (474 aa)
	APICC_03681	NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
	APICC_04222	Protein fem-1 B. (654 aa)
	APICC_04019	COP9 signalosome complex subunit. (187 aa)
	APICC_04053	NEDD8-activating enzyme E1 regulatory subunit. (539 aa)
	APICC_00532	COP9 signalosome complex subunit. (290 aa)
	APICC_02706	NEDD8-like protein. (77 aa)
	APICC_03659	COP9 signalosome complex subunit. (338 aa)
	APICC_00239	Transcription elongation factor B polypeptide. (117 aa)
	APICC_00138	COP9 signalosome complex subunit. (411 aa)
	APICC_06396	Leucine-rich repeat-containing protein. (344 aa)
	APICC_01803	Anaphase-promoting complex subunit. (84 aa)
	APICC_05179	Transcription elongation factor B polypeptide; Belongs to the SKP1 family. (122 aa)
	APICC_00131	COP9 signalosome complex subunit. (344 aa)
	APICC_04337	UbiquitinA. (150 aa)
	APICC_02518	Ubiquitin protein. (347 aa)
	APICC_07103	Kelch protein. (661 aa)
	APICC_05716	NEDD8-conjugating enzyme UBE2F; Belongs to the ubiquitin-conjugating enzyme family. (182 aa)
	APICC_06030	Cullin-2; Belongs to the cullin family. (755 aa)
	APICC_08964	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (261 aa)
	APICC_06127	Cullin-3; Belongs to the cullin family. (813 aa)
	APICC_07120	Cullin-1; Belongs to the cullin family. (777 aa)
	APICC_02195	NEDD8-activating enzyme E1 catalytic subunit. (484 aa)
	APICC_03979	F-box only protein. (306 aa)
	APICC_08081	F-box/WD repeat-containing protein. (512 aa)
	APICC_03037	COP9 signalosome complex subunit. (445 aa)
	APICC_05603	COP9 signalosome complex subunit. (477 aa)
	APICC_03137	S-phase kinase-associated protein; Belongs to the SKP1 family. (162 aa)
	APICC_02847	JmjC domain-containing histone demethylation protein. (983 aa)
	APICC_03198	RING-boxA. (113 aa)
	APICC_00045	COP9 signalosome complex subunit. (456 aa)

Your Current Organism:

Apis cerana

NCBI taxonomy Id: 94128
Other names: A. cerana cerana, Apis cerana cerana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APICC_00045	APICC_00131	A0A2A3ETD5	A0A2A3EEN3	COP9 signalosome complex subunit.	COP9 signalosome complex subunit.	0.999
APICC_00045	APICC_00138	A0A2A3ETD5	A0A2A3ECM8	COP9 signalosome complex subunit.	COP9 signalosome complex subunit.	0.999
APICC_00045	APICC_00239	A0A2A3ETD5	A0A2A3EBT4	COP9 signalosome complex subunit.	Transcription elongation factor B polypeptide.	0.813
APICC_00045	APICC_00532	A0A2A3ETD5	A0A2A3E991	COP9 signalosome complex subunit.	COP9 signalosome complex subunit.	0.995
APICC_00045	APICC_00834	A0A2A3ETD5	A0A2A3E750	COP9 signalosome complex subunit.	Peptidylprolyl isomerase.	0.609
APICC_00045	APICC_01007	A0A2A3ETD5	A0A2A3E702	COP9 signalosome complex subunit.	Sterol regulatory element-binding protein cleavage-activating protein.	0.598
APICC_00045	APICC_01372	A0A2A3ETD5	A0A2A3E3L7	COP9 signalosome complex subunit.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.677
APICC_00045	APICC_01432	A0A2A3ETD5	A0A2A3E4L4	COP9 signalosome complex subunit.	F-box/WD repeat-containing protein.	0.598
APICC_00045	APICC_01803	A0A2A3ETD5	A0A2A3EDY6	COP9 signalosome complex subunit.	Anaphase-promoting complex subunit.	0.836
APICC_00045	APICC_02195	A0A2A3ETD5	A0A2A3ENJ2	COP9 signalosome complex subunit.	NEDD8-activating enzyme E1 catalytic subunit.	0.502
APICC_00045	APICC_02518	A0A2A3ETD5	A0A2A3EHC9	COP9 signalosome complex subunit.	Ubiquitin protein.	0.685
APICC_00045	APICC_02706	A0A2A3ETD5	A0A2A3E9N1	COP9 signalosome complex subunit.	NEDD8-like protein.	0.938
APICC_00045	APICC_02847	A0A2A3ETD5	A0A2A3EST0	COP9 signalosome complex subunit.	JmjC domain-containing histone demethylation protein.	0.562
APICC_00045	APICC_03037	A0A2A3ETD5	A0A2A3ESB6	COP9 signalosome complex subunit.	COP9 signalosome complex subunit.	0.999
APICC_00045	APICC_03137	A0A2A3ETD5	A0A2A3ESH7	COP9 signalosome complex subunit.	S-phase kinase-associated protein; Belongs to the SKP1 family.	0.671
APICC_00045	APICC_03198	A0A2A3ETD5	A0A2A3ET71	COP9 signalosome complex subunit.	RING-boxA.	0.967
APICC_00045	APICC_03659	A0A2A3ETD5	A0A2A3EA71	COP9 signalosome complex subunit.	COP9 signalosome complex subunit.	0.999
APICC_00045	APICC_03681	A0A2A3ETD5	A0A2A3E7T6	COP9 signalosome complex subunit.	NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.	0.445
APICC_00045	APICC_03979	A0A2A3ETD5	A0A2A3ENT9	COP9 signalosome complex subunit.	F-box only protein.	0.701
APICC_00045	APICC_04019	A0A2A3ETD5	A0A2A3E8S2	COP9 signalosome complex subunit.	COP9 signalosome complex subunit.	0.998