node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APICC_01461 | APICC_06254 | A0A2A3E4M7 | A0A2A3EH56 | L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. | Alpha-aminoadipic semialdehyde synthase. | 0.641 |
APICC_01569 | APICC_02655 | A0A2A3EP58 | A0A2A3EG72 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | Homocysteine S-methyltransferase ybgG. | 0.428 |
APICC_01569 | APICC_02656 | A0A2A3EP58 | A0A2A3EHV7 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | Homocysteine S-methyltransferase. | 0.428 |
APICC_01569 | APICC_03510 | A0A2A3EP58 | A0A2A3EBW4 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.550 |
APICC_01569 | APICC_04866 | A0A2A3EP58 | A0A2A3EMN7 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.956 |
APICC_01569 | APICC_05258 | A0A2A3EP58 | A0A2A3EF32 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | Aspartate aminotransferase. | 0.408 |
APICC_01569 | APICC_06007 | A0A2A3EP58 | A0A2A3EHN8 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | 0.988 |
APICC_01569 | APICC_06427 | A0A2A3EP58 | A0A2A3EEP1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | 0.945 |
APICC_01569 | APICC_07513 | A0A2A3EP58 | A0A2A3EME8 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | Methylenetetrahydrofolate reductase. | 0.402 |
APICC_02655 | APICC_01569 | A0A2A3EG72 | A0A2A3EP58 | Homocysteine S-methyltransferase ybgG. | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | 0.428 |
APICC_02655 | APICC_02656 | A0A2A3EG72 | A0A2A3EHV7 | Homocysteine S-methyltransferase ybgG. | Homocysteine S-methyltransferase. | 0.910 |
APICC_02655 | APICC_04866 | A0A2A3EG72 | A0A2A3EMN7 | Homocysteine S-methyltransferase ybgG. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.638 |
APICC_02655 | APICC_05258 | A0A2A3EG72 | A0A2A3EF32 | Homocysteine S-methyltransferase ybgG. | Aspartate aminotransferase. | 0.583 |
APICC_02655 | APICC_06007 | A0A2A3EG72 | A0A2A3EHN8 | Homocysteine S-methyltransferase ybgG. | Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). | 0.424 |
APICC_02655 | APICC_06427 | A0A2A3EG72 | A0A2A3EEP1 | Homocysteine S-methyltransferase ybgG. | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | 0.573 |
APICC_02655 | APICC_07513 | A0A2A3EG72 | A0A2A3EME8 | Homocysteine S-methyltransferase ybgG. | Methylenetetrahydrofolate reductase. | 0.973 |
APICC_02656 | APICC_01569 | A0A2A3EHV7 | A0A2A3EP58 | Homocysteine S-methyltransferase. | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). | 0.428 |
APICC_02656 | APICC_02655 | A0A2A3EHV7 | A0A2A3EG72 | Homocysteine S-methyltransferase. | Homocysteine S-methyltransferase ybgG. | 0.910 |
APICC_02656 | APICC_04866 | A0A2A3EHV7 | A0A2A3EMN7 | Homocysteine S-methyltransferase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | 0.638 |
APICC_02656 | APICC_05258 | A0A2A3EHV7 | A0A2A3EF32 | Homocysteine S-methyltransferase. | Aspartate aminotransferase. | 0.583 |