(31 nodes) Hedgehog signaling pathway - fly network (Apis cerana)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APICC_06617	Casein kinase I isoform alpha; Belongs to the protein kinase superfamily. (357 aa)
	APICC_05274	RCC1 and BTB domain-containing protein. (533 aa)
	APICC_04962	Protein patched. (1186 aa)
	APICC_09723	Interference hedgehog. (1103 aa)
	APICC_07120	Cullin-1; Belongs to the cullin family. (777 aa)
	APICC_09261	RCC1 and BTB domain-containing protein. (506 aa)
	APICC_08081	F-box/WD repeat-containing protein. (512 aa)
	APICC_06459	Protein kinase shaggy; Belongs to the protein kinase superfamily. (456 aa)
	APICC_09427	Kinesin protein costa. (849 aa)
	APICC_03137	S-phase kinase-associated protein; Belongs to the SKP1 family. (162 aa)
	APICC_03198	RING-boxA. (113 aa)
	APICC_09370	Casein kinase I isoform gamma-1; Belongs to the protein kinase superfamily. (472 aa)
	APICC_02095	TWiK family of potassium channels protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (416 aa)
	APICC_05804	Actin-binding protein IPP. (638 aa)
	APICC_05811	Protein smoothened; Belongs to the G-protein coupled receptor Fz/Smo family. (1070 aa)
	APICC_08644	Actin-binding protein IPP. (641 aa)
	APICC_07470	Casein kinase I isoform epsilon. (862 aa)
	APICC_07944	Casein kinase I isoform delta. (787 aa)
	APICC_01041	Protein roadkill. (438 aa)
	APICC_09161	Protein roadkill. (361 aa)
	APICC_03304	TD and POZ domain-containing. (250 aa)
	APICC_03414	Protein cubitus interruptus. (1483 aa)
	APICC_09145	E3 ubiquitin-protein ligase. (992 aa)
	APICC_08577	cAMP-dependent protein kinase catalytic subunit; Belongs to the protein kinase superfamily. (415 aa)
	APICC_03709	Serine/threonine-protein kinase fused. (801 aa)
	APICC_00963	Suppressor of fused. (431 aa)
	APICC_04276	Sonic hedgehog protein A. (361 aa)
	APICC_04017	Ring canal kelch. (1089 aa)
	Dpp	Protein decapentaplegic. (390 aa)
	APICC_06127	Cullin-3; Belongs to the cullin family. (813 aa)
	APICC_00521	TWiK family of potassium channels protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (556 aa)

Your Current Organism:

Apis cerana

NCBI taxonomy Id: 94128
Other names: A. cerana cerana, Apis cerana cerana

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APICC_00963	APICC_01041	A0A2A3E752	A0A2A3EEX6	Suppressor of fused.	Protein roadkill.	0.725
APICC_00963	APICC_03137	A0A2A3E752	A0A2A3ESH7	Suppressor of fused.	S-phase kinase-associated protein; Belongs to the SKP1 family.	0.636
APICC_00963	APICC_03198	A0A2A3E752	A0A2A3ET71	Suppressor of fused.	RING-boxA.	0.589
APICC_00963	APICC_03304	A0A2A3E752	A0A2A3ECM4	Suppressor of fused.	TD and POZ domain-containing.	0.667
APICC_00963	APICC_03414	A0A2A3E752	A0A2A3ECC5	Suppressor of fused.	Protein cubitus interruptus.	0.990
APICC_00963	APICC_03709	A0A2A3E752	A0A2A3EA70	Suppressor of fused.	Serine/threonine-protein kinase fused.	0.998
APICC_00963	APICC_04276	A0A2A3E752	A0A2A3E6G9	Suppressor of fused.	Sonic hedgehog protein A.	0.628
APICC_00963	APICC_04962	A0A2A3E752	A0A2A3EML7	Suppressor of fused.	Protein patched.	0.752
APICC_00963	APICC_05811	A0A2A3E752	A0A2A3EJV5	Suppressor of fused.	Protein smoothened; Belongs to the G-protein coupled receptor Fz/Smo family.	0.915
APICC_00963	APICC_06127	A0A2A3E752	A0A2A3ELM8	Suppressor of fused.	Cullin-3; Belongs to the cullin family.	0.868
APICC_00963	APICC_06459	A0A2A3E752	A0A2A3EQE6	Suppressor of fused.	Protein kinase shaggy; Belongs to the protein kinase superfamily.	0.793
APICC_00963	APICC_06617	A0A2A3E752	A0A2A3ECH7	Suppressor of fused.	Casein kinase I isoform alpha; Belongs to the protein kinase superfamily.	0.729
APICC_00963	APICC_07120	A0A2A3E752	A0A2A3EN89	Suppressor of fused.	Cullin-1; Belongs to the cullin family.	0.729
APICC_00963	APICC_08577	A0A2A3E752	A0A2A3EBH8	Suppressor of fused.	cAMP-dependent protein kinase catalytic subunit; Belongs to the protein kinase superfamily.	0.868
APICC_00963	APICC_09145	A0A2A3E752	A0A2A3EBV2	Suppressor of fused.	E3 ubiquitin-protein ligase.	0.549
APICC_00963	APICC_09161	A0A2A3E752	A0A2A3ECN4	Suppressor of fused.	Protein roadkill.	0.667
APICC_00963	APICC_09427	A0A2A3E752	A0A2A3ESC9	Suppressor of fused.	Kinesin protein costa.	0.950
APICC_01041	APICC_00963	A0A2A3EEX6	A0A2A3E752	Protein roadkill.	Suppressor of fused.	0.725
APICC_01041	APICC_03198	A0A2A3EEX6	A0A2A3ET71	Protein roadkill.	RING-boxA.	0.717
APICC_01041	APICC_03414	A0A2A3EEX6	A0A2A3ECC5	Protein roadkill.	Protein cubitus interruptus.	0.985