87 items (Mola mola) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMMOP00000003545	Transforming growth factor beta; Belongs to the TGF-beta family. (423 aa)
	ENSMMOP00000003486	PR domain containing 1a, with ZNF domain. (833 aa)
	ENSMMOP00000003198	Forkhead box L1. (334 aa)
	ENSMMOP00000003138	Mediator complex subunit 24. (961 aa)
	ENSMMOP00000002724	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (827 aa)
	ENSMMOP00000001322	Myogenic factor. (237 aa)
	ENSMMOP00000001226	Uncharacterized protein; Belongs to the potassium channel family. (589 aa)
	ENSMMOP00000000663	Yes-associated protein 1. (436 aa)
	ENSMMOP00000000619	Uncharacterized protein. (768 aa)
	ENSMMOP00000000203	H2.0-like homeo box 1 (Drosophila). (357 aa)
	ENSMMOP00000000043	Heart and neural crest derivatives expressed 2. (227 aa)
	ENSMMOP00000001294	Homeobox domain-containing protein. (290 aa)
	ENSMMOP00000028305	Polycystic kidney disease 1a. (4503 aa)
	ENSMMOP00000027357	SAP domain-containing protein. (884 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (708 aa)
	VANGL2	Vang-like protein. (525 aa)
	ENSMMOP00000027105	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (560 aa)
	ENSMMOP00000026520	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (439 aa)
	ENSMMOP00000026055	Kruppel-like factor 5b. (380 aa)
	ENSMMOP00000025407	Uncharacterized protein. (228 aa)
	ENSMMOP00000025085	Uncharacterized protein. (314 aa)
	ENSMMOP00000024805	BCL2 apoptosis regulator b. (207 aa)
	ENSMMOP00000023933	Forkhead box F2a. (376 aa)
	ENSMMOP00000023846	Ectopic P-granules autophagy protein 5 homolog (C. elegans). (2434 aa)
	ENSMMOP00000023570	Uncharacterized protein. (246 aa)
	ENSMMOP00000023094	GATA binding protein 5. (383 aa)
	ENSMMOP00000022985	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (425 aa)
	ENSMMOP00000022282	VPS52 subunit of GARP complex. (683 aa)
	ENSMMOP00000022141	Fork-head domain-containing protein. (361 aa)
	ENSMMOP00000021841	Forkhead box F2b. (347 aa)
	ENSMMOP00000021546	Retinoblastoma 1. (877 aa)
	ENSMMOP00000021508	WT1 interacting protein. (696 aa)
	ENSMMOP00000021249	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (685 aa)
	ENSMMOP00000021010	Mix paired-like homeobox. (289 aa)
	ENSMMOP00000020769	GATA binding protein 4. (263 aa)
	ENSMMOP00000020424	Transcription factor 21. (168 aa)
	ENSMMOP00000019628	T-box transcription factor 1. (460 aa)
	ENSMMOP00000019610	PR/SET domain 1. (736 aa)
	ENSMMOP00000019252	Kruppel-like factor 5 like. (418 aa)
	ENSMMOP00000019056	T-box transcription factor Ta. (424 aa)
	ENSMMOP00000018694	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (643 aa)
	IKZF5	IKAROS family zinc finger 5. (409 aa)
	ENSMMOP00000017722	PR domain containing 1b, with ZNF domain. (603 aa)
	ENSMMOP00000017570	Chromodomain helicase DNA binding protein 8. (2490 aa)
	ENSMMOP00000017047	Nipped-B protein. (2360 aa)
	ENSMMOP00000017037	Uncharacterized protein. (104 aa)
	ENSMMOP00000017004	Vang-like protein. (526 aa)
	ENSMMOP00000016003	G protein-coupled receptor 22b. (434 aa)
	ENSMMOP00000015805	Anterior gradient 2. (166 aa)
	ENSMMOP00000015752	Protein kinase domain containing, cytoplasmic b. (480 aa)
	ENSMMOP00000015676	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (62 aa)
	ENSMMOP00000015594	Inhibitor of DNA binding 2a. (136 aa)
	ENSMMOP00000015413	Histone domain-containing protein. (136 aa)
	ENSMMOP00000015336	Mindbomb E3 ubiquitin protein ligase 1. (973 aa)
	ENSMMOP00000015331	GATA binding protein 6. (491 aa)
	ENSMMOP00000014970	WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (399 aa)
	ENSMMOP00000014617	Abelson helper integration site 1. (786 aa)
	ENSMMOP00000013778	NK2 homeobox 3. (335 aa)
	ENSMMOP00000013776	NK3 homeobox 3. (167 aa)
	ENSMMOP00000013690	FZ domain-containing protein. (283 aa)
	ENSMMOP00000012996	Salvador family WW domain containing protein 1. (400 aa)
	ENSMMOP00000012488	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	ENSMMOP00000012419	Nipped-B protein. (2674 aa)
	ENSMMOP00000011259	Fibroblast growth factor receptor. (780 aa)
	ENSMMOP00000010920	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (147 aa)
	ENSMMOP00000010594	IKAROS family zinc finger 5. (436 aa)
	ENSMMOP00000010561	Progesterone immunomodulatory binding factor 1. (456 aa)
	ENSMMOP00000010276	Uncharacterized protein. (595 aa)
	ENSMMOP00000009128	Achaete-scute family bHLH transcription factor 1a. (200 aa)
	ENSMMOP00000008687	Transforming growth factor, beta 2. (117 aa)
	ENSMMOP00000008683	Transforming growth factor, beta 2. (277 aa)
	ENSMMOP00000008444	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (628 aa)
	ENSMMOP00000007420	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (459 aa)
	ENSMMOP00000007310	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (579 aa)
	ENSMMOP00000006812	RNA-binding region (RNP1, RRM) containing 3. (467 aa)
	ENSMMOP00000006520	Forkhead box A3. (466 aa)
	ENSMMOP00000006349	Uncharacterized protein. (370 aa)
	ENSMMOP00000006029	UTP25 small subunit processor component. (716 aa)
	ENSMMOP00000005633	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (469 aa)
	ENSMMOP00000005226	Homeobox protein. (268 aa)
	ENSMMOP00000005203	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (341 aa)
	ENSMMOP00000005140	NK3 homeobox 2. (142 aa)
	ENSMMOP00000004950	Secreted frizzled-related protein 2. (295 aa)
	ENSMMOP00000004423	Musculin (activated B-cell factor-1). (141 aa)
	ENSMMOP00000004196	Inversin. (810 aa)
	ENSMMOP00000003806	T-box transcription factor 20. (440 aa)
	ENSMMOP00000003736	Pancreatic and duodenal homeobox 1. (239 aa)

Your Current Organism:

Mola mola

NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMMOP00000000043	ENSMMOP00000003806	ENSMMOP00000000043	ENSMMOP00000003806	Heart and neural crest derivatives expressed 2.	T-box transcription factor 20.	0.579
ENSMMOP00000000043	ENSMMOP00000005140	ENSMMOP00000000043	ENSMMOP00000005140	Heart and neural crest derivatives expressed 2.	NK3 homeobox 2.	0.539
ENSMMOP00000000043	ENSMMOP00000013776	ENSMMOP00000000043	ENSMMOP00000013776	Heart and neural crest derivatives expressed 2.	NK3 homeobox 3.	0.423
ENSMMOP00000000043	ENSMMOP00000015331	ENSMMOP00000000043	ENSMMOP00000015331	Heart and neural crest derivatives expressed 2.	GATA binding protein 6.	0.706
ENSMMOP00000000043	ENSMMOP00000020769	ENSMMOP00000000043	ENSMMOP00000020769	Heart and neural crest derivatives expressed 2.	GATA binding protein 4.	0.739
ENSMMOP00000000043	ENSMMOP00000023094	ENSMMOP00000000043	ENSMMOP00000023094	Heart and neural crest derivatives expressed 2.	GATA binding protein 5.	0.727
ENSMMOP00000000043	ENSMMOP00000027357	ENSMMOP00000000043	ENSMMOP00000027357	Heart and neural crest derivatives expressed 2.	SAP domain-containing protein.	0.556
ENSMMOP00000000619	ENSMMOP00000021249	ENSMMOP00000000619	ENSMMOP00000021249	Uncharacterized protein.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.568
ENSMMOP00000000619	EZH1	ENSMMOP00000000619	ENSMMOP00000027197	Uncharacterized protein.	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.568
ENSMMOP00000000663	ENSMMOP00000007310	ENSMMOP00000000663	ENSMMOP00000007310	Yes-associated protein 1.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.936
ENSMMOP00000000663	ENSMMOP00000012996	ENSMMOP00000000663	ENSMMOP00000012996	Yes-associated protein 1.	Salvador family WW domain containing protein 1.	0.892
ENSMMOP00000000663	ENSMMOP00000018694	ENSMMOP00000000663	ENSMMOP00000018694	Yes-associated protein 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.936
ENSMMOP00000000663	ENSMMOP00000019056	ENSMMOP00000000663	ENSMMOP00000019056	Yes-associated protein 1.	T-box transcription factor Ta.	0.412
ENSMMOP00000000663	ENSMMOP00000021546	ENSMMOP00000000663	ENSMMOP00000021546	Yes-associated protein 1.	Retinoblastoma 1.	0.417
ENSMMOP00000000663	ENSMMOP00000027105	ENSMMOP00000000663	ENSMMOP00000027105	Yes-associated protein 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.529
ENSMMOP00000001226	ENSMMOP00000008444	ENSMMOP00000001226	ENSMMOP00000008444	Uncharacterized protein; Belongs to the potassium channel family.	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	0.898
ENSMMOP00000001294	ENSMMOP00000006520	ENSMMOP00000001294	ENSMMOP00000006520	Homeobox domain-containing protein.	Forkhead box A3.	0.574
ENSMMOP00000001294	ENSMMOP00000015331	ENSMMOP00000001294	ENSMMOP00000015331	Homeobox domain-containing protein.	GATA binding protein 6.	0.480
ENSMMOP00000001322	ENSMMOP00000003486	ENSMMOP00000001322	ENSMMOP00000003486	Myogenic factor.	PR domain containing 1a, with ZNF domain.	0.613
ENSMMOP00000001322	ENSMMOP00000015594	ENSMMOP00000001322	ENSMMOP00000015594	Myogenic factor.	Inhibitor of DNA binding 2a.	0.424