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dnaA dnaA fadA1 fadA1 rpoN1 rpoN1 petC petC petB petB petA petA ctaA ctaA wza1 wza1 Bpet0261 Bpet0261 Bpet0305 Bpet0305 frdB frdB Bpet0400 Bpet0400 sdhC sdhC Bpet0404 Bpet0404 cydA cydA cydB cydB Bpet0458 Bpet0458 phoR phoR phoB phoB tolC tolC Bpet0535 Bpet0535 Bpet0536 Bpet0536 Bpet0537 Bpet0537 Bpet0665 Bpet0665 Bpet0666 Bpet0666 Bpet0670 Bpet0670 cyt cyt Bpet0680 Bpet0680 Bpet0752 Bpet0752 Bpet0753 Bpet0753 Bpet0754 Bpet0754 Bpet0848 Bpet0848 Bpet0849 Bpet0849 Bpet0855 Bpet0855 Bpet0885 Bpet0885 Bpet0889 Bpet0889 Bpet0895 Bpet0895 Bpet0896 Bpet0896 Bpet0897 Bpet0897 Bpet0898 Bpet0898 csrA csrA Bpet1523 Bpet1523 risS risS risA risA mucD mucD Bpet1942 Bpet1942 Bpet2000 Bpet2000 Bpet2054 Bpet2054 fliC fliC fliA fliA flhD flhD flhC flhC motA motA cheY1 cheY1 cheA cheA cheW cheW tsr1 tsr1 cheR cheR cheB cheB cheY2 cheY2 Bpet2109 Bpet2109 flgM flgM tsr2 tsr2 tsr3 tsr3 fadA3 fadA3 Bpet2230 Bpet2230 Bpet2235 Bpet2235 glnA glnA ntrB ntrB ntrC ntrC wza2 wza2 citE citE rpoN3 rpoN3 glnD glnD fecR1 fecR1 Bpet2691 Bpet2691 regS regS regR regR ptpA ptpA Bpet2787 Bpet2787 Bpet2788 Bpet2788 Bpet2835 Bpet2835 glnB1 glnB1 Bpet2946 Bpet2946 fadA5 fadA5 fixJ fixJ ccoN3 ccoN3 ccoQ ccoQ ccoN2 ccoN2 ccoN1 ccoN1 Bpet3271 Bpet3271 fadA6 fadA6 fadA7 fadA7 Bpet3520 Bpet3520 pstS pstS Bpet3537 Bpet3537 Bpet3821 Bpet3821 narI1 narI1 narJ1 narJ1 narH1 narH1 narG1 narG1 Bpet3832 Bpet3832 Bpet3833 Bpet3833 ampC ampC fadA9 fadA9 Bpet4351 Bpet4351 Bpet4352 Bpet4352 Bpet4353 Bpet4353 Bpet4367 Bpet4367 Bpet4450 Bpet4450 fecR2 fecR2 bvgS1 bvgS1 bvgA bvgA bvgS2 bvgS2 atoE atoE Bpet4572 Bpet4572 Bpet4573 Bpet4573 Bpet4574 Bpet4574 copS copS Bpet4609 Bpet4609 Bpet4610 Bpet4610 Bpet4611 Bpet4611 Bpet4744 Bpet4744 Bpet4764 Bpet4764 Bpet4765 Bpet4765 Bpet4766 Bpet4766 Bpet4767 Bpet4767 Bpet4768 Bpet4768 Bpet4831 Bpet4831 Bpet4980 Bpet4980 Bpet4981 Bpet4981 Bpet4982 Bpet4982 Bpet4983 Bpet4983 Bpet4984 Bpet4984 narG2 narG2 narH2 narH2 narJ2 narJ2 narI2 narI2 narX narX narL narL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaAChromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (478 aa)
fadA1Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
rpoN1RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (479 aa)
petCCytochrome C1 precursor. (284 aa)
petBUbiquinol-cytochrome c reductase cytochrome b subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (462 aa)
petAUbiquinol-cytochrome C reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (213 aa)
ctaAPutative cytochrome oxidase assembly protein. (337 aa)
wza1Outer membrane protein involved in polysaccharide. (385 aa)
Bpet0261Putative transmembrane sensor histidine kinase transcription regulator protein. (367 aa)
Bpet0305Putative membrane protein. (501 aa)
frdBFumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (265 aa)
Bpet0400Hypothetical protein predicted by Glimmer/Critica. (113 aa)
sdhCSuccinate dehydrogenase cytochrome b-556 subunit. (117 aa)
Bpet0404Putative succinate dehydrogenase flavoprotein subunit. (577 aa)
cydACytochrome D ubiquinol oxidase subunit I. (525 aa)
cydBCytochrome D ubiquinol oxidase subunit II. (384 aa)
Bpet0458Conserved hypothetical protein; Predicted outer membrane lipoprotein. (40 aa)
phoRPhosphate regulon sensor protein. (432 aa)
phoBResponse regulator. (232 aa)
tolCOuter membrane export protein. (444 aa)
Bpet0535HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (416 aa)
Bpet0536AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1029 aa)
Bpet0537AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1038 aa)
Bpet0665Two component response regulator. (228 aa)
Bpet0666Two-component system histidine kinase. (511 aa)
Bpet0670Putative membrane protein. (501 aa)
cytCytochrome c family protein. (117 aa)
Bpet0680Putative cytochrome c. (133 aa)
Bpet0752Uncharacterized protein conserved in bacteria. (317 aa)
Bpet0753Unnamed protein product. (161 aa)
Bpet0754Uncharacterized protein conserved in bacteria. (495 aa)
Bpet0848Putative Membrane protein. (210 aa)
Bpet0849Putative Membrane protein. (423 aa)
Bpet0855Putative Citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family. (274 aa)
Bpet0885Putative 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Bpet0889Membrane protein, TRAP-domain containing. (439 aa)
Bpet0895Putative transmembrane cytochrome oxidase. (447 aa)
Bpet0896Putative cytochrome oxidase. (344 aa)
Bpet0897Two-component sensor kinase. (499 aa)
Bpet0898Probable transcriptional regulator. (233 aa)
csrACarbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (65 aa)
Bpet1523Transposition-related fusion-protein; Belongs to the DegT/DnrJ/EryC1 family. (683 aa)
risSRisS protein; Signal transduction histidine kinase. (464 aa)
risAResponse regulator protein. (244 aa)
mucDSerine protease; Belongs to the peptidase S1C family. (489 aa)
Bpet1942Putative inner membrane protein. (425 aa)
Bpet2000Putative prepilin protein. (204 aa)
Bpet2054Two-component system histidine kinase. (458 aa)
fliCFlagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (501 aa)
fliAFlagellar-specific RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (246 aa)
flhDFlagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (134 aa)
flhCFlagellar transcriptional activator; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (201 aa)
motAFlagellar motor component MotA. (291 aa)
cheY1Chemotaxis protein CheY. (126 aa)
cheAChemotaxis protein CheA. (702 aa)
cheWChemotaxis protein CheW. (166 aa)
tsr1Tsr1 protein; Methyl-accepting chemotaxis protein. (573 aa)
cheRChemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (286 aa)
cheBChemotaxis response regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (352 aa)
cheY2Chemotaxis protein CheY. (129 aa)
Bpet2109Methyl-accepting transducer domain-containing protein; Unnamed protein product. (523 aa)
flgMNegative regulator of flagellin synthesis. (120 aa)
tsr2Tsr2 protein; Methyl-accepting chemotaxis protein. (654 aa)
tsr3Tsr3 protein; Methyl-accepting chemotaxis protein. (575 aa)
fadA3FadA3 protein; Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Bpet2230Putative membrane protein (TRAP-type transport system, large permease component). (427 aa)
Bpet2235Putative membrane protein (TRAP dicarboxylate transporter DctM subunit). (433 aa)
glnAGlutamine synthetase. (470 aa)
ntrBNitrogen regulation protein NR(II). (355 aa)
ntrCNitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (503 aa)
wza2Outer membrane protein involved in polysaccharide. (367 aa)
citECitrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family. (308 aa)
rpoN3RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (489 aa)
glnDprotein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (870 aa)
fecR1Putative transmembrane sensor. (329 aa)
Bpet2691Putative sensor histidine kinase. (385 aa)
regSTwo component system sensor kinase. (408 aa)
regRTwo component system response regulator. (183 aa)
ptpALow molecular weight protein-tyrosine-phosphatase. (163 aa)
Bpet2787Putative Integral membrane protein. (168 aa)
Bpet2788Putative Membrane protein (TRAP-type C4-dicarboxylate transport system). (424 aa)
Bpet2835Probable two-component response regulator. (258 aa)
glnB1Nitrogen regulatory protein P-II; Belongs to the P(II) protein family. (112 aa)
Bpet2946Putative outer membrane proton channel. (301 aa)
fadA5Probable 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
fixJTwo-component response regulator. (208 aa)
ccoN3Cytochrome C oxidase subunit; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (311 aa)
ccoQCcoQ protein. (55 aa)
ccoN2Cytochrome C oxidase subunit. (231 aa)
ccoN1Cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family. (491 aa)
Bpet3271Putative TRAP-type C4-dicarboxylate transport system, large permease component. (438 aa)
fadA6FadA6 protein; Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
fadA7Putative 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
Bpet3520TonB-dependent outer membrane receptor. (739 aa)
pstSPhosphate-binding periplasmic protein precursor; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
Bpet3537Putative regulatory lipoprotein. (440 aa)
Bpet3821TRAP-type C4-dicarboxylate transport system, large permease component. (432 aa)
narI1Nitrate reductase gamma chain. (228 aa)
narJ1Nitrate reductase delta chain. (240 aa)
narH1Nitrate reductase beta chain. (516 aa)
narG1Nitrate reductase 1, alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1252 aa)
Bpet3832Putative transmembrane cytochrome oxidase. (467 aa)
Bpet3833Putative cytochrome oxidase. (335 aa)
ampCBeta-lactamase. (389 aa)
fadA9FadA9 protein; Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
Bpet4351Uncharacterized protein conserved in bacteria. (339 aa)
Bpet4352Hypothetical protein. (171 aa)
Bpet4353Uncharacterized protein conserved in bacteria. (513 aa)
Bpet4367Putative 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
Bpet4450Putative Citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family. (288 aa)
fecR2Transmembrane sensor. (331 aa)
bvgS1Virulence sensor protein. (599 aa)
bvgAVirulence factors transcription regulator. (208 aa)
bvgS2Virulence sensor protein. (684 aa)
atoEShort-chain fatty acids transporter. (445 aa)
Bpet4572Putative membrane fusion protein silB precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (501 aa)
Bpet4573AcrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1055 aa)
Bpet4574Probable Cation efflux system protein cusF precursor. (86 aa)
copSTwo-component sensor kinase; Member of a two-component regulatory system. (460 aa)
Bpet4609Two-component response regulator. (232 aa)
Bpet4610Two-component sensor kinase; Member of a two-component regulatory system. (448 aa)
Bpet4611Two-component response regulator. (186 aa)
Bpet4744Cyclic nucleotide-binding protein. (229 aa)
Bpet4764Two-component response regulator. (210 aa)
Bpet4765Two-component sensor kinase. (680 aa)
Bpet4766C4-dicarboxylate-binding periplasmic protein precursor. (334 aa)
Bpet4767C4-dicarboxylate transport system, small permease component. (195 aa)
Bpet4768Probable C4-dicarboxylate transporter large subunit. (540 aa)
Bpet4831Putative UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (360 aa)
Bpet4980Putative membrane protein. (508 aa)
Bpet4981Inner membrane protein. (160 aa)
Bpet4982Tricarboxylate transport protein tctC. (331 aa)
Bpet4983Sensor histidine kinase TctE. (525 aa)
Bpet4984Response regulator protein. (225 aa)
narG2Nitrate reductase 1, alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1246 aa)
narH2Nitrate reductase, beta chain. (521 aa)
narJ2Nitrate reductase, delta chain. (215 aa)
narI2Nitrate reductase, gamma chain. (227 aa)
narXNitrate/nitrite sensor protein. (644 aa)
narLNitrate/nitrite response regulator protein. (220 aa)
Your Current Organism:
Bordetella petrii
NCBI taxonomy Id: 94624
Other names: B. petrii, Bordetella petrii von Wintzingerode et al. 2001, CCUG 43448, DSM 12804, strain Se-1111R
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