(26 nodes) Homologous recombination network (Bordetella petrii)

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second shell of interactors

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Your Input:
	dnaN	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] (369 aa)
	priA	Primosomal protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (693 aa)
	dnaQ	DNA polymerase III, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (241 aa)
	ruvB	Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (353 aa)
	ruvA	Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (190 aa)
	ruvC	Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (182 aa)
	ssb1	Ssb1 protein; Single-stranded DNA-binding protein. (150 aa)
	ssb2	Ssb2 protein; Single-stranded DNA-binding protein. (147 aa)
	ssb3	Ssb3 protein; Single-stranded DNA-binding protein. (146 aa)
	recO	DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (195 aa)
	holC	DNA polymerase III, chi subunit. (147 aa)
	recA	RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa)
	recG	ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (696 aa)
	holB	DNA polymerase III, delta' subunit. (368 aa)
	recJ	single-stranded-DNA-specific exonuclease. (695 aa)
	priB	Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (107 aa)
	dnaE2	DNA polymerase III, alpha subunit. (1163 aa)
	polA	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (948 aa)
	holA	Putative DNA polymerase III, delta subunit. (350 aa)
	polC	Putative exonuclease. (177 aa)
	recR	Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (202 aa)
	dnaX	DNA polymerase III subunit Tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (736 aa)
	ssb4	Single-strand binding protein. (159 aa)
	ssb5	Ssb5 protein. (170 aa)
	ssb6	Ssb6 protein; Single-stranded DNA-binding protein. (146 aa)
	ssb7	Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (169 aa)

Your Current Organism:

Bordetella petrii

NCBI taxonomy Id: 94624
Other names: B. petrii, Bordetella petrii von Wintzingerode et al. 2001, CCUG 43448, DSM 12804, strain Se-1111R

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dnaE2	dnaN	Bpet3118	Bpet0002	DNA polymerase III, alpha subunit.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.990
dnaE2	dnaQ	Bpet3118	Bpet0634	DNA polymerase III, alpha subunit.	DNA polymerase III, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.982
dnaE2	dnaX	Bpet3118	Bpet3553	DNA polymerase III, alpha subunit.	DNA polymerase III subunit Tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.986
dnaE2	holA	Bpet3118	Bpet3326	DNA polymerase III, alpha subunit.	Putative DNA polymerase III, delta subunit.	0.983
dnaE2	holB	Bpet3118	Bpet2503	DNA polymerase III, alpha subunit.	DNA polymerase III, delta' subunit.	0.986
dnaE2	holC	Bpet3118	Bpet1770	DNA polymerase III, alpha subunit.	DNA polymerase III, chi subunit.	0.986
dnaE2	polA	Bpet3118	Bpet3126	DNA polymerase III, alpha subunit.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.649
dnaE2	polC	Bpet3118	Bpet3353	DNA polymerase III, alpha subunit.	Putative exonuclease.	0.969
dnaE2	recA	Bpet3118	Bpet2056	DNA polymerase III, alpha subunit.	RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.438
dnaE2	recR	Bpet3118	Bpet3551	DNA polymerase III, alpha subunit.	Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.	0.607
dnaE2	ssb1	Bpet3118	Bpet1036	DNA polymerase III, alpha subunit.	Ssb1 protein; Single-stranded DNA-binding protein.	0.576
dnaE2	ssb2	Bpet3118	Bpet1297	DNA polymerase III, alpha subunit.	Ssb2 protein; Single-stranded DNA-binding protein.	0.576
dnaE2	ssb3	Bpet3118	Bpet1447	DNA polymerase III, alpha subunit.	Ssb3 protein; Single-stranded DNA-binding protein.	0.576
dnaE2	ssb4	Bpet3118	Bpet3771	DNA polymerase III, alpha subunit.	Single-strand binding protein.	0.809
dnaE2	ssb5	Bpet3118	Bpet4213	DNA polymerase III, alpha subunit.	Ssb5 protein.	0.576
dnaE2	ssb6	Bpet3118	Bpet4306	DNA polymerase III, alpha subunit.	Ssb6 protein; Single-stranded DNA-binding protein.	0.576
dnaE2	ssb7	Bpet3118	Bpet4905	DNA polymerase III, alpha subunit.	Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.	0.816
dnaN	dnaE2	Bpet0002	Bpet3118	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	DNA polymerase III, alpha subunit.	0.990
dnaN	dnaQ	Bpet0002	Bpet0634	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	DNA polymerase III, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.992
dnaN	dnaX	Bpet0002	Bpet3553	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	DNA polymerase III subunit Tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.994