(40 nodes) Mixed, incl. Cobalamin (Cbl) metabolism, and Aldehyde catabolic process network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_00137	Fe2OG dioxygenase domain-containing protein. (315 aa)
	PTSG_00556	Uncharacterized protein; Belongs to the DapA family. (312 aa)
	PTSG_00656	Methylmalonyl-CoA mutase. (650 aa)
	PTSG_01862	Uncharacterized protein. (723 aa)
	PTSG_02033	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (328 aa)
	PTSG_01350	Uncharacterized protein. (274 aa)
	PTSG_01559	Uncharacterized protein. (616 aa)
	PTSG_01568	Methylmalonyl-CoA epimerase. (150 aa)
	PTSG_02380	Uncharacterized protein. (482 aa)
	PTSG_11878	Aldo-keto reductase. (234 aa)
	PTSG_03122	Lactamase_B domain-containing protein. (257 aa)
	PTSG_03222	Galactonolactone dehydrogenase. (585 aa)
	PTSG_03854	FAD linked oxidase domain-containing protein. (560 aa)
	PTSG_03640	Aldo_ket_red domain-containing protein. (328 aa)
	PTSG_04041	Uncharacterized protein. (273 aa)
	PTSG_04066	Lactamase_B domain-containing protein. (307 aa)
	PTSG_04958	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (307 aa)
	PTSG_05439	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (172 aa)
	PTSG_05440	2-Hacid_dh_C domain-containing protein. (74 aa)
	PTSG_05659	Uncharacterized protein. (714 aa)
	PTSG_06176	Beta-lactamase domain-containing protein. (577 aa)
	PTSG_05957	Uncharacterized protein. (300 aa)
	PTSG_06101	Uncharacterized protein. (773 aa)
	PTSG_07084	LAO/AO transport system ATPase. (345 aa)
	PTSG_06707	Formaldehyde dehydrogenase. (355 aa)
	PTSG_12477	Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (252 aa)
	PTSG_06723	Gametogenetin binding protein 2. (890 aa)
	PTSG_06922	Lactamase_B domain-containing protein. (304 aa)
	PTSG_07820	Beta-lactamase domain-containing protein. (523 aa)
	PTSG_07737	Hyperpolarization-activated ion channel protein. (849 aa)
	PTSG_07414	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (314 aa)
	PTSG_12899	Aldo_ket_red domain-containing protein. (269 aa)
	PTSG_09580	D-isomer specific 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
	PTSG_12879	2-Hacid_dh_C domain-containing protein. (92 aa)
	PTSG_10029	Aldehyde reductase. (328 aa)
	PTSG_10786	2,5-didehydrogluconate reductase. (306 aa)
	PTSG_10148	Aldo/keto reductase. (382 aa)
	PTSG_10299	Voltage-gated potassium channel subunit beta-1. (357 aa)
	PTSG_10579	Uncharacterized protein. (643 aa)
	PTSG_11014	Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (272 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00137	PTSG_01350	F2TVM3	F2U033	Fe2OG dioxygenase domain-containing protein.	Uncharacterized protein.	0.423
PTSG_00137	PTSG_10148	F2TVM3	F2UQF9	Fe2OG dioxygenase domain-containing protein.	Aldo/keto reductase.	0.567
PTSG_00137	PTSG_10299	F2TVM3	F2UQW9	Fe2OG dioxygenase domain-containing protein.	Voltage-gated potassium channel subunit beta-1.	0.567
PTSG_00556	PTSG_01350	F2TWT7	F2U033	Uncharacterized protein; Belongs to the DapA family.	Uncharacterized protein.	0.423
PTSG_00556	PTSG_10148	F2TWT7	F2UQF9	Uncharacterized protein; Belongs to the DapA family.	Aldo/keto reductase.	0.567
PTSG_00556	PTSG_10299	F2TWT7	F2UQW9	Uncharacterized protein; Belongs to the DapA family.	Voltage-gated potassium channel subunit beta-1.	0.567
PTSG_00656	PTSG_01350	F2TX40	F2U033	Methylmalonyl-CoA mutase.	Uncharacterized protein.	0.589
PTSG_00656	PTSG_01568	F2TX40	F2U0Q8	Methylmalonyl-CoA mutase.	Methylmalonyl-CoA epimerase.	0.974
PTSG_00656	PTSG_02033	F2TX40	F2TZP1	Methylmalonyl-CoA mutase.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.420
PTSG_00656	PTSG_06101	F2TX40	F2UDP3	Methylmalonyl-CoA mutase.	Uncharacterized protein.	0.462
PTSG_00656	PTSG_07084	F2TX40	F2UE04	Methylmalonyl-CoA mutase.	LAO/AO transport system ATPase.	0.936
PTSG_00656	PTSG_11014	F2TX40	F2USG0	Methylmalonyl-CoA mutase.	Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.	0.442
PTSG_00656	PTSG_12477	F2TX40	F2UEK6	Methylmalonyl-CoA mutase.	Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.	0.442
PTSG_01350	PTSG_00137	F2U033	F2TVM3	Uncharacterized protein.	Fe2OG dioxygenase domain-containing protein.	0.423
PTSG_01350	PTSG_00556	F2U033	F2TWT7	Uncharacterized protein.	Uncharacterized protein; Belongs to the DapA family.	0.423
PTSG_01350	PTSG_00656	F2U033	F2TX40	Uncharacterized protein.	Methylmalonyl-CoA mutase.	0.589
PTSG_01350	PTSG_01568	F2U033	F2U0Q8	Uncharacterized protein.	Methylmalonyl-CoA epimerase.	0.501
PTSG_01350	PTSG_03640	F2U033	F2U663	Uncharacterized protein.	Aldo_ket_red domain-containing protein.	0.645
PTSG_01350	PTSG_06101	F2U033	F2UDP3	Uncharacterized protein.	Uncharacterized protein.	0.837
PTSG_01350	PTSG_07084	F2U033	F2UE04	Uncharacterized protein.	LAO/AO transport system ATPase.	0.574

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