(39 nodes) Steroid biosynthetic process, and Secondary metabolite biosynthetic process network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_11590	Lathosterol oxidase; Belongs to the sterol desaturase family. (214 aa)
	PTSG_00494	Methyltransferase type 11. (289 aa)
	PTSG_00551	C-8 sterol isomerase. (244 aa)
	PTSG_00994	Peptidylprolyl isomerase. (819 aa)
	PTSG_01052	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (286 aa)
	PTSG_01809	Methyltransferase type 11. (362 aa)
	PTSG_01854	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (374 aa)
	PTSG_02040	Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
	PTSG_03087	HpcH_HpaI domain-containing protein. (315 aa)
	PTSG_04556	FAD_binding_3 domain-containing protein. (507 aa)
	PTSG_04648	Ergosterol biosynthesis ERG4/ERG24 family protein. (785 aa)
	PTSG_05313	HMG_CoA_synt_N domain-containing protein. (137 aa)
	PTSG_05190	Uncharacterized protein. (256 aa)
	PTSG_05764	Methyltransf_12 domain-containing protein. (257 aa)
	PTSG_06155	Uncharacterized protein; Belongs to the cytochrome P450 family. (563 aa)
	PTSG_06237	Sterol desaturase; Belongs to the sterol desaturase family. (280 aa)
	PTSG_05848	Farnesyl-diphosphate farnesyltransferase 1. (429 aa)
	PTSG_07059	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (276 aa)
	PTSG_07145	Nucleoside-diphosphate-sugar epimerase. (345 aa)
	PTSG_12548	FAD_binding_3 domain-containing protein. (372 aa)
	PTSG_06618	3Beta_HSD domain-containing protein. (617 aa)
	PTSG_07553	FAD_binding_3 domain-containing protein. (446 aa)
	PTSG_08099	Transmembrane 7 superfamily member 2. (425 aa)
	PTSG_07314	3-hydroxy-3-methylglutaryl coenzyme A reductase. (590 aa)
	PTSG_08301	Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family. (537 aa)
	PTSG_08303	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (362 aa)
	PTSG_08398	Sterol desaturase; Belongs to the sterol desaturase family. (305 aa)
	PTSG_08436	Reductase with NAD or NADP as acceptor; Belongs to the 3-beta-HSD family. (399 aa)
	PTSG_09512	Methyltransferase type 11. (312 aa)
	PTSG_09100	FAD_binding_3 domain-containing protein. (458 aa)
	PTSG_09918	Uncharacterized protein; Belongs to the cytochrome P450 family. (505 aa)
	PTSG_09923	D-alanine-D-alanine ligase. (829 aa)
	PTSG_10510	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (309 aa)
	PTSG_10799	Uncharacterized protein. (976 aa)
	PTSG_10778	Uncharacterized protein; Belongs to the cytochrome P450 family. (469 aa)
	PTSG_10876	Cytochrome P450 reductase. (649 aa)
	PTSG_10993	Uncharacterized protein. (180 aa)
	PTSG_11027	Epimerase domain-containing protein. (366 aa)
	PTSG_11175	Cycloartenol synthase; Belongs to the terpene cyclase/mutase family. (599 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00494	PTSG_00551	F2TWM4	F2TWT2	Methyltransferase type 11.	C-8 sterol isomerase.	0.592
PTSG_00494	PTSG_05848	F2TWM4	F2UCY9	Methyltransferase type 11.	Farnesyl-diphosphate farnesyltransferase 1.	0.582
PTSG_00494	PTSG_06155	F2TWM4	F2UC39	Methyltransferase type 11.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.462
PTSG_00494	PTSG_08301	F2TWM4	F2UJB0	Methyltransferase type 11.	Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family.	0.462
PTSG_00494	PTSG_11175	F2TWM4	F2USM8	Methyltransferase type 11.	Cycloartenol synthase; Belongs to the terpene cyclase/mutase family.	0.471
PTSG_00551	PTSG_00494	F2TWT2	F2TWM4	C-8 sterol isomerase.	Methyltransferase type 11.	0.592
PTSG_00551	PTSG_01052	F2TWT2	F2TY93	C-8 sterol isomerase.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.976
PTSG_00551	PTSG_01809	F2TWT2	F2TZ09	C-8 sterol isomerase.	Methyltransferase type 11.	0.592
PTSG_00551	PTSG_01854	F2TWT2	F2TZ53	C-8 sterol isomerase.	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.	0.794
PTSG_00551	PTSG_04556	F2TWT2	F2U7S2	C-8 sterol isomerase.	FAD_binding_3 domain-containing protein.	0.409
PTSG_00551	PTSG_04648	F2TWT2	F2U813	C-8 sterol isomerase.	Ergosterol biosynthesis ERG4/ERG24 family protein.	0.760
PTSG_00551	PTSG_05190	F2TWT2	F2UAS0	C-8 sterol isomerase.	Uncharacterized protein.	0.862
PTSG_00551	PTSG_05313	F2TWT2	F2UA28	C-8 sterol isomerase.	HMG_CoA_synt_N domain-containing protein.	0.705
PTSG_00551	PTSG_05848	F2TWT2	F2UCY9	C-8 sterol isomerase.	Farnesyl-diphosphate farnesyltransferase 1.	0.560
PTSG_00551	PTSG_06155	F2TWT2	F2UC39	C-8 sterol isomerase.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.878
PTSG_00551	PTSG_06237	F2TWT2	F2UCC0	C-8 sterol isomerase.	Sterol desaturase; Belongs to the sterol desaturase family.	0.862
PTSG_00551	PTSG_06618	F2TWT2	F2UFI0	C-8 sterol isomerase.	3Beta_HSD domain-containing protein.	0.794
PTSG_00551	PTSG_07059	F2TWT2	F2UDX7	C-8 sterol isomerase.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.986
PTSG_00551	PTSG_07314	F2TWT2	F2UJ23	C-8 sterol isomerase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.445
PTSG_00551	PTSG_07553	F2TWT2	F2UH36	C-8 sterol isomerase.	FAD_binding_3 domain-containing protein.	0.409

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