(60 nodes) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, and Starch and sucrose metabolism network (Salpingoeca rosetta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PTSG_00083	Aamy domain-containing protein. (467 aa)
	PTSG_00284	Starch branching enzyme II. (530 aa)
	PTSG_00365	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (375 aa)
	PTSG_00388	UDP-glucose 6-dehydrogenase. (463 aa)
	PTSG_01636	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (265 aa)
	PTSG_01773	RHM3 protein. (509 aa)
	PTSG_02013	Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (300 aa)
	PTSG_01381	Phosphoglucomutase 2; Belongs to the phosphohexose mutase family. (539 aa)
	PTSG_11727	Uncharacterized protein. (1067 aa)
	PTSG_01101	ALG11 protein. (515 aa)
	PTSG_01106	Alpha-1,3-mannosyltransferase ALG3 isoform d. (403 aa)
	PTSG_02376	GDP-D-mannose pyrophosphorylase. (386 aa)
	PTSG_02450	4,5-dihydroxyphthalate dehydrogenase. (424 aa)
	PTSG_02082	Uncharacterized protein. (915 aa)
	PTSG_02588	Glycosyltransferase 28 domain containing 1. (204 aa)
	PTSG_03135	Uncharacterized protein. (581 aa)
	PTSG_03244	Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (389 aa)
	PTSG_03338	UDP-n-acteylglucosamine pyrophosphorylase. (485 aa)
	PTSG_03803	SH3 domain-containing protein. (726 aa)
	PTSG_03853	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (255 aa)
	PTSG_03493	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (433 aa)
	PTSG_12102	Glycogenin-1. (390 aa)
	PTSG_04401	P-type domain-containing protein. (596 aa)
	PTSG_04936	Uncharacterized protein. (399 aa)
	PTSG_05303	Uncharacterized protein. (667 aa)
	PTSG_12270	Dolichyl-phosphate beta-glucosyltransferase. (165 aa)
	PTSG_12271	Uncharacterized protein. (64 aa)
	PTSG_06230	Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (533 aa)
	PTSG_06236	Uncharacterized protein. (484 aa)
	PTSG_07123	Uncharacterized protein; Belongs to the phosphohexose mutase family. (598 aa)
	PTSG_07164	Alpha-1,3-mannosyltransferase ALG2. (426 aa)
	PTSG_07251	UTP--glucose-1-phosphate uridylyltransferase. (494 aa)
	PTSG_07252	Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family. (573 aa)
	PTSG_06745	Uncharacterized protein. (251 aa)
	PTSG_06504	Galactokinase 2. (469 aa)
	PTSG_06524	NTP_transferase domain-containing protein. (460 aa)
	PTSG_07554	UDP-glucuronate decarboxylase 1. (449 aa)
	PTSG_07582	OTU domain-containing protein. (393 aa)
	PTSG_07662	Uncharacterized protein. (289 aa)
	PTSG_08009	Uncharacterized protein. (417 aa)
	PTSG_08028	S5A_REDUCTASE domain-containing protein. (276 aa)
	PTSG_08298	NTP_transferase domain-containing protein. (291 aa)
	PTSG_08531	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (899 aa)
	PTSG_12762	Uncharacterized protein. (3036 aa)
	PTSG_09670	Uncharacterized protein. (414 aa)
	PTSG_09053	acidPPc domain-containing protein. (165 aa)
	PTSG_09313	NAD-dependent epimerase/dehydratase. (413 aa)
	PTSG_09317	Phosphoacetylglucosamine mutase. (537 aa)
	PTSG_09418	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (343 aa)
	PTSG_12858	Uncharacterized protein. (273 aa)
	PTSG_12859	Glycos_transf_1 domain-containing protein. (138 aa)
	PTSG_09875	GDP-mannose 4. (362 aa)
	PTSG_09925	CBM21 domain-containing protein. (518 aa)
	PTSG_09972	NAD-dependent epimerase/dehydratase. (344 aa)
	PTSG_10207	RmlD_sub_bind domain-containing protein. (462 aa)
	PTSG_10237	Uncharacterized protein. (1194 aa)
	PTSG_10326	Beta-lactamase. (435 aa)
	PTSG_11324	PPC domain-containing protein. (178 aa)
	PTSG_13178	GDP-L-fucose synthase. (313 aa)
	PTSG_11395	Mannosyltransferase. (490 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00083	PTSG_00284	F2TVG8	F2TW18	Aamy domain-containing protein.	Starch branching enzyme II.	0.979
PTSG_00083	PTSG_01101	F2TVG8	F2U0T6	Aamy domain-containing protein.	ALG11 protein.	0.412
PTSG_00083	PTSG_01381	F2TVG8	F2U065	Aamy domain-containing protein.	Phosphoglucomutase 2; Belongs to the phosphohexose mutase family.	0.600
PTSG_00083	PTSG_02082	F2TVG8	F2U2K8	Aamy domain-containing protein.	Uncharacterized protein.	0.965
PTSG_00083	PTSG_03493	F2TVG8	F2U5S0	Aamy domain-containing protein.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.412
PTSG_00083	PTSG_03853	F2TVG8	F2U5K5	Aamy domain-containing protein.	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.	0.539
PTSG_00083	PTSG_04401	F2TVG8	F2U8G2	Aamy domain-containing protein.	P-type domain-containing protein.	0.944
PTSG_00083	PTSG_04936	F2TVG8	F2U918	Aamy domain-containing protein.	Uncharacterized protein.	0.429
PTSG_00083	PTSG_05303	F2TVG8	F2UA18	Aamy domain-containing protein.	Uncharacterized protein.	0.429
PTSG_00083	PTSG_06504	F2TVG8	F2UG01	Aamy domain-containing protein.	Galactokinase 2.	0.402
PTSG_00083	PTSG_07123	F2TVG8	F2UE45	Aamy domain-containing protein.	Uncharacterized protein; Belongs to the phosphohexose mutase family.	0.518
PTSG_00083	PTSG_07164	F2TVG8	F2UE90	Aamy domain-containing protein.	Alpha-1,3-mannosyltransferase ALG2.	0.421
PTSG_00083	PTSG_08531	F2TVG8	F2UJY5	Aamy domain-containing protein.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.969
PTSG_00083	PTSG_09317	F2TVG8	F2UMA3	Aamy domain-containing protein.	Phosphoacetylglucosamine mutase.	0.517
PTSG_00083	PTSG_10237	F2TVG8	F2UQQ0	Aamy domain-containing protein.	Uncharacterized protein.	0.959
PTSG_00083	PTSG_12858	F2TVG8	F2UN68	Aamy domain-containing protein.	Uncharacterized protein.	0.412
PTSG_00083	PTSG_12859	F2TVG8	F2UN69	Aamy domain-containing protein.	Glycos_transf_1 domain-containing protein.	0.412
PTSG_00284	PTSG_00083	F2TW18	F2TVG8	Starch branching enzyme II.	Aamy domain-containing protein.	0.979
PTSG_00284	PTSG_01101	F2TW18	F2U0T6	Starch branching enzyme II.	ALG11 protein.	0.645
PTSG_00284	PTSG_01381	F2TW18	F2U065	Starch branching enzyme II.	Phosphoglucomutase 2; Belongs to the phosphohexose mutase family.	0.932

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