(37 nodes) ERAD pathway, and ATPase, AAA-type, core network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_01706	UBX domain-containing protein. (457 aa)
	PTSG_01991	Cell division cycle protein 48; Belongs to the AAA ATPase family. (805 aa)
	PTSG_01086	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (244 aa)
	PTSG_02114	AAA domain-containing protein. (664 aa)
	PTSG_02184	RING-type domain-containing protein. (539 aa)
	PTSG_02246	AZUL domain-containing protein. (720 aa)
	PTSG_02644	Uncharacterized protein; Belongs to the AAA ATPase family. (626 aa)
	PTSG_03785	ATPase AFG2 protein. (852 aa)
	PTSG_03511	Uncharacterized protein. (632 aa)
	PTSG_03725	Uncharacterized protein. (572 aa)
	PTSG_04191	UBX domain-containing protein. (741 aa)
	PTSG_04296	Uncharacterized protein. (266 aa)
	PTSG_04621	UBX domain-containing protein. (309 aa)
	PTSG_05037	AAA domain-containing protein. (526 aa)
	PTSG_04717	UBA domain-containing protein. (127 aa)
	PTSG_12287	PUB domain-containing protein. (321 aa)
	PTSG_05652	Uncharacterized protein. (788 aa)
	PTSG_06152	Uncharacterized protein. (387 aa)
	PTSG_06259	Uncharacterized protein. (304 aa)
	PTSG_12395	Uncharacterized protein. (133 aa)
	PTSG_06926	Uncharacterized protein. (403 aa)
	PTSG_06462	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (304 aa)
	PTSG_12671	UBX domain-containing protein. (485 aa)
	PTSG_12692	Uncharacterized protein. (1009 aa)
	PTSG_08313	Uncharacterized protein. (176 aa)
	PTSG_12705	Uncharacterized protein. (447 aa)
	PTSG_12744	Uncharacterized protein. (1679 aa)
	PTSG_12809	Uncharacterized protein. (491 aa)
	PTSG_09518	RING-type domain-containing protein. (233 aa)
	PTSG_09044	UBX domain-containing protein. (433 aa)
	PTSG_09399	Uncharacterized protein; Belongs to the AAA ATPase family. (864 aa)
	PTSG_09774	CUE domain-containing protein. (438 aa)
	PTSG_10082	Erlin-1. (321 aa)
	PTSG_10915	Mosaic virus helicase domain binding protein; Belongs to the AAA ATPase family. (650 aa)
	PTSG_10842	Ubiquitin thioesterase OTU1. (306 aa)
	PTSG_11104	MPN domain-containing protein. (550 aa)
	PTSG_11482	Uncharacterized protein. (223 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_01086	PTSG_01991	F2U0S0	F2TZJ8	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Cell division cycle protein 48; Belongs to the AAA ATPase family.	0.944
PTSG_01086	PTSG_02114	F2U0S0	F2U192	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	AAA domain-containing protein.	0.473
PTSG_01086	PTSG_02184	F2U0S0	F2U1G4	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	RING-type domain-containing protein.	0.997
PTSG_01086	PTSG_02246	F2U0S0	F2U1M5	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	AZUL domain-containing protein.	0.777
PTSG_01086	PTSG_02644	F2U0S0	F2U2W5	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.732
PTSG_01086	PTSG_03511	F2U0S0	F2U5U0	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.473
PTSG_01086	PTSG_03725	F2U0S0	F2U6E4	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.839
PTSG_01086	PTSG_03785	F2U0S0	F2U5D7	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	ATPase AFG2 protein.	0.944
PTSG_01086	PTSG_04191	F2U0S0	F2U6V2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBX domain-containing protein.	0.539
PTSG_01086	PTSG_04296	F2U0S0	F2U759	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.796
PTSG_01086	PTSG_04621	F2U0S0	F2U7Y7	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBX domain-containing protein.	0.539
PTSG_01086	PTSG_04717	F2U0S0	F2U9I1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBA domain-containing protein.	0.673
PTSG_01086	PTSG_05037	F2U0S0	F2U9C1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	AAA domain-containing protein.	0.732
PTSG_01086	PTSG_05652	F2U0S0	F2UBU2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.472
PTSG_01086	PTSG_06152	F2U0S0	F2UC36	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.966
PTSG_01086	PTSG_06259	F2U0S0	F2UCE2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.796
PTSG_01086	PTSG_06462	F2U0S0	F2UFV7	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.994
PTSG_01086	PTSG_06926	F2U0S0	F2UF73	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.871
PTSG_01086	PTSG_08313	F2U0S0	F2UJC2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.871
PTSG_01086	PTSG_09399	F2U0S0	F2UMI4	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.474

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