(34 nodes) RNA Polymerase II Transcription Elongation network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_00101	Uncharacterized protein. (295 aa)
	PTSG_00566	S1 motif domain-containing protein. (171 aa)
	PTSG_00805	Protein kinase domain-containing protein. (1538 aa)
	PTSG_00952	Cyclin N-terminal domain-containing protein. (294 aa)
	PTSG_11763	Uncharacterized protein. (612 aa)
	PTSG_01958	DNA-directed RNA polymerase II subunit RPB3. (271 aa)
	PTSG_01263	Uncharacterized protein. (508 aa)
	PTSG_01493	Major larval glue protein. (447 aa)
	PTSG_11687	TFIIS N-terminal domain-containing protein. (279 aa)
	PTSG_02173	DNA-directed RNA polymerase II subunit J. (202 aa)
	PTSG_02277	Uncharacterized protein. (490 aa)
	PTSG_02289	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1193 aa)
	PTSG_02413	Plus3 domain-containing protein. (645 aa)
	PTSG_03204	Uncharacterized protein. (269 aa)
	PTSG_04225	S1 motif domain-containing protein. (1774 aa)
	PTSG_04238	Transcription elongation factor SPT4. (114 aa)
	PTSG_03974	Uncharacterized protein. (864 aa)
	PTSG_04053	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (797 aa)
	PTSG_12409	Uncharacterized protein. (1584 aa)
	PTSG_06010	Uncharacterized protein. (58 aa)
	PTSG_07096	CYCLIN domain-containing protein; Belongs to the cyclin family. (355 aa)
	PTSG_07137	CMGC/CDK protein kinase. (501 aa)
	PTSG_07243	Uncharacterized protein. (996 aa)
	PTSG_06563	Uncharacterized protein. (509 aa)
	PTSG_07810	Polymerase II polypeptide E. (201 aa)
	PTSG_07709	TPR_REGION domain-containing protein. (1102 aa)
	PTSG_08052	Uncharacterized protein. (698 aa)
	PTSG_07432	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1834 aa)
	PTSG_09578	Uncharacterized protein. (1297 aa)
	PTSG_08993	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (190 aa)
	PTSG_12984	Transcription elongation factor SPT5. (1092 aa)
	PTSG_10432	TFIIS-type domain-containing protein; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (222 aa)
	PTSG_10802	RPOL4c domain-containing protein. (153 aa)
	PTSG_11312	DNA-directed RNA polymerase I. (69 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00101	PTSG_00566	F2TVI9	F2TWU7	Uncharacterized protein.	S1 motif domain-containing protein.	0.862
PTSG_00101	PTSG_01263	F2TVI9	F2TZU5	Uncharacterized protein.	Uncharacterized protein.	0.768
PTSG_00101	PTSG_01493	F2TVI9	F2U0I0	Uncharacterized protein.	Major larval glue protein.	0.834
PTSG_00101	PTSG_01958	F2TVI9	F2TZG3	Uncharacterized protein.	DNA-directed RNA polymerase II subunit RPB3.	0.944
PTSG_00101	PTSG_02173	F2TVI9	F2U1F2	Uncharacterized protein.	DNA-directed RNA polymerase II subunit J.	0.836
PTSG_00101	PTSG_02277	F2TVI9	F2U1R0	Uncharacterized protein.	Uncharacterized protein.	0.999
PTSG_00101	PTSG_02289	F2TVI9	F2U1S2	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.902
PTSG_00101	PTSG_02413	F2TVI9	F2U248	Uncharacterized protein.	Plus3 domain-containing protein.	0.997
PTSG_00101	PTSG_03204	F2TVI9	F2U4I6	Uncharacterized protein.	Uncharacterized protein.	0.783
PTSG_00101	PTSG_04053	F2TVI9	F2U7M9	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.996
PTSG_00101	PTSG_04225	F2TVI9	F2U6Y5	Uncharacterized protein.	S1 motif domain-containing protein.	0.859
PTSG_00101	PTSG_04238	F2TVI9	F2U6Z8	Uncharacterized protein.	Transcription elongation factor SPT4.	0.907
PTSG_00101	PTSG_06010	F2TVI9	F2UDF0	Uncharacterized protein.	Uncharacterized protein.	0.841
PTSG_00101	PTSG_06563	F2TVI9	F2UG61	Uncharacterized protein.	Uncharacterized protein.	0.999
PTSG_00101	PTSG_07243	F2TVI9	F2UEG8	Uncharacterized protein.	Uncharacterized protein.	0.988
PTSG_00101	PTSG_07432	F2TVI9	F2UIP5	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.834
PTSG_00101	PTSG_07709	F2TVI9	F2UHJ3	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.999
PTSG_00101	PTSG_07810	F2TVI9	F2UGE2	Uncharacterized protein.	Polymerase II polypeptide E.	0.713
PTSG_00101	PTSG_08052	F2TVI9	F2UHV2	Uncharacterized protein.	Uncharacterized protein.	0.471
PTSG_00101	PTSG_08993	F2TVI9	F2ULW6	Uncharacterized protein.	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.	0.465

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